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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
Results1 to 6 of 6 Research Studies Displayed
Bao Y, Ryan AM, Shao H
Generic initiation and antidepressant therapy adherence under Medicare Part D.
This study assessed the effects of initiating antidepressant treatment with a generic versus a branded prescription (generic initiation) on adherence to antidepressant therapy for the treatment of depression. It found that starting patients with generics had benefits for antidepressant adherence by lowering out-of-pocket costs for all patients and by mitigating the effect of the Part D coverage gap faced by patients not receiving low-income subsidies.
Citation: Bao Y, Ryan AM, Shao H . Generic initiation and antidepressant therapy adherence under Medicare Part D. Am J Manag Care 2013 Dec;19(12):989-98..
Keywords: Medication, Depression, Medicare, Patient Adherence/Compliance
Stuart B, Davidoff A, Erten M
AHRQ Author: Davidoff A
How Medicare Part D benefit phases affect adherence with evidence-based medications following acute myocardial infarction.
The authors assessed the impact of Medicare Part D benefit phases on adherence with evidence-based medications after hospitalization for an acute myocardial infarction (AMI). They found that as the Part D doughnut hole is gradually filled in by 2020, Medicare Part D enrollees with critical diseases such as AMI who rely heavily on brand name drugs are likely to exhibit modest increases in adherence, while those reliant on generic drugs are less likely to be affected.
Citation: Stuart B, Davidoff A, Erten M . How Medicare Part D benefit phases affect adherence with evidence-based medications following acute myocardial infarction. Health Serv Res 2013 Dec;48(6 Pt 1):1960-77. doi: 10.1111/1475-6773.12073.
Keywords: Evidence-Based Practice, Medicare, Medication, Heart Disease and Health, Patient Adherence/Compliance
Bergeron AR, Webb JR, Serper M
Impact of electronic prescribing on medication use in ambulatory care.
This study investigated differences before and after rollout of electronic prescribing (e-prescribing) in (1) patients’ primary adherence to newly prescribed medications, (2) patients' understanding of how to use their medications, and (3) multiple pharmacy use. It found an increase in abandoned prescriptions immediately following the implementation of e-prescribing. However, with time, these issues were resolved and even improved to rates lower than baseline.
Citation: Bergeron AR, Webb JR, Serper M . Impact of electronic prescribing on medication use in ambulatory care. Am J Manag Care 2013 Dec;19(12):1012-7..
Keywords: Electronic Prescribing (E-Prescribing), Ambulatory Care and Surgery, Patient Adherence/Compliance, Medication
Soeters HM, Napravnik S, Zakharova OM
Opportunities for sexual transmission of antiretroviral drug resistance among HIV-infected patients in care.
The researchers had two aims: to examine patterns of nonadherence, high-risk sexual behavior, detectable HIV viraemia and antiretroviral drug resistance, and to identify factors associated with potential transmission of drug-resistant HIV among patients engaged in HIV care. They found that a small but significant proportion of clinic patients with viraemia and documented resistant HIV continue to engage in sexual behaviors that place others at risk for transmitted drug resistance.
Citation: Soeters HM, Napravnik S, Zakharova OM . Opportunities for sexual transmission of antiretroviral drug resistance among HIV-infected patients in care. AIDS 2013 Nov 28;27(18):2873-81. doi: 10.1097/01.aids.0000433240.78739.30..
Keywords: Human Immunodeficiency Virus (HIV), Lifestyle Changes, Patient Adherence/Compliance
Galarraga O, Genberg BL, Martin RA
Conditional economic incentives to improve HIV treatment adherence: literature review and theoretical considerations.
This review summarizes various theories from micro- and behavioral-economics to social and clinical psychology that may help to understand how conditional economic incentives (CEI) work, and how they may be integrated with theories of health behavior that focus more on internal motivation. It concluded that appropriate CEI can help patients adhere to HIV treatment in the short-term, while incentives are in place.
Citation: Galarraga O, Genberg BL, Martin RA . Conditional economic incentives to improve HIV treatment adherence: literature review and theoretical considerations. AIDS Behav. 2013 Sep;17(7):2283-92. doi: 10.1007/s10461-013-0415-2..
Keywords: Human Immunodeficiency Virus (HIV), Patient Self-Management, Chronic Conditions, Medication, Patient Adherence/Compliance
Osborn CY, Mayberry LS, Wallston KA
Understanding patient portal use: implications for medication management.
The authors sought to (1) understand who uses an existing patient portal and reasons for use and nonuse, (2) understand how portal users are using a portal to manage their medications, and (3) explore participants' ideas for improving portal functionality for medication management and adherence support. They found that patients use portals to manage their medications, are enthusiastic about further leveraging portals to support medication management and adherence, and those who use a portal more frequently have better glycemic control.
AHRQ-funded; HS018168; HS013833.
Citation: Osborn CY, Mayberry LS, Wallston KA . Understanding patient portal use: implications for medication management. J Med Internet Res 2013 Jul 3;15(7):e133. doi: 10.2196/jmir.2589.
Keywords: Diabetes, Health Information Technology (HIT), Medication, Patient Adherence/Compliance, Web-Based