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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
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Shrestha S, Foxman B, Weinberger DM
AHRQ Author: Steiner C
Identifying the interaction between influenza and pneumococcal pneumonia using incidence data.
The authors integrated weekly incidence reports and a mechanistic transmission model within a likelihood-based inference framework to characterize the nature, timing, and magnitude of the interaction between influenza and pneumococcal pneumonia. They found support for a strong but short-lived interaction, with influenza infection increasing susceptibility to pneumococcal pneumonia ~100-fold. They inferred modest population-level impacts arising from strong processes at the level of an individual.
Citation: Shrestha S, Foxman B, Weinberger DM . Identifying the interaction between influenza and pneumococcal pneumonia using incidence data. Sci Transl Med 2013 Jun 26;5(191):191ra84. doi: 10.1126/scitranslmed.3005982.
Keywords: Healthcare Cost and Utilization Project (HCUP), Influenza, Pneumonia