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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedBennette CS, Ramsey SD, McDermott CL
Predicting low accrual in the National Cancer Institute's cooperative group clinical trials.
The study’s objective was to evaluate the empirical relationship and predictive properties of putative risk factors for low accrual in the National Cancer Institute's (NCI's) Cooperative Group Program, now the National Clinical Trials Network (NCTN). It identified multiple characteristics of NCTN-sponsored trials associated with low accrual and developed a prediction model that can provide a useful estimate of accrual risk based on these factors.
AHRQ-funded; HS023340.
Citation: Bennette CS, Ramsey SD, McDermott CL .
Predicting low accrual in the National Cancer Institute's cooperative group clinical trials.
J Natl Cancer Inst 2016 Feb;108(2). doi: 10.1093/jnci/djv324.
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Keywords: Research Methodologies, Risk
Haukoos JS, Lewis RJ
The propensity score.
The authors discuss studies by Rozé et al and Huybrechts et al that used propensity score matching and propensity score stratification, respectively. They argue that although both methods are more valid in terms of balancing study groups than simple matching or stratification based on baseline characteristics, they vary in their ability to minimize bias. In general, propensity score matching minimizes bias to a greater extent than propensity score stratification.
AHRQ-funded; HS021749.
Citation: Haukoos JS, Lewis RJ .
The propensity score.
JAMA 2015 Oct 20;314(15):1637-8. doi: 10.1001/jama.2015.13480..
Keywords: Research Methodologies, Data, Risk