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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 3 of 3 Research Studies DisplayedMiligkos M, Bannuru RR, Alkofide H
Leukotriene-receptor antagonists versus placebo in the treatment of asthma in adults and adolescents: a systematic review and meta-analysis.
The purpose of this study was to determine the benefits and harms of leukotriene-receptor antagonists (LTRAs) as monotherapy or in combination with inhaled corticosteroids compared with placebo in adults and adolescents with asthma. It found that leukotriene-receptor antagonists as monotherapy improved asthma control compared with placebo, but which patients are most likely to respond to treatment with LTRAs remains unclear.
AHRQ-funded; HS021396.
Citation: Miligkos M, Bannuru RR, Alkofide H .
Leukotriene-receptor antagonists versus placebo in the treatment of asthma in adults and adolescents: a systematic review and meta-analysis.
Ann Intern Med 2015 Nov 17;163(10):756-67. doi: 10.7326/m15-1059.
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Keywords: Asthma, Children/Adolescents, Medication, Comparative Effectiveness
Wechsler ME, Yawn BP, Fuhlbrigge AL
Anticholinergic vs long-acting beta-agonist in combination with inhaled corticosteroids in Black adults with asthma: the BELT randomized clinical trial.
The researchers compared the effectiveness and safety of tiotropium vs long-acting beta agonists (LABAs), when used with inhaled corticosteroids (ICS) in black adults with asthma. They found that among black adults with asthma treated with ICS, adding a LABA did not improve time to asthma exacerbation compared with adding tiotropium. These findings were not affected by polymorphisms at the Arg16Gly locus of ADRB2.
AHRQ-funded; HS019408.
Citation: Wechsler ME, Yawn BP, Fuhlbrigge AL .
Anticholinergic vs long-acting beta-agonist in combination with inhaled corticosteroids in Black adults with asthma: the BELT randomized clinical trial.
JAMA 2015 Oct 27;314(16):1720-30. doi: 10.1001/jama.2015.13277..
Keywords: Comparative Effectiveness, Patient Safety, Asthma, Medication
Mowrer JL, Tapp H, Ludden T
Patients' and providers' perceptions of asthma and asthma care: a qualitative study.
The primary goal of this qualitative study was to further explore patient and provider perceptions of asthma and asthma care as part of a larger Asthma Comparative Effectiveness Study. Three overarching themes, with a variety of subthemes, emerged as the main findings of this study. The three main themes were Cost/Economic Barriers/Process, Self-Governance/Adherence and Education.
AHRQ-funded; HS019946.
Citation: Mowrer JL, Tapp H, Ludden T .
Patients' and providers' perceptions of asthma and asthma care: a qualitative study.
J Asthma 2015;52(9):949-56. doi: 10.3109/02770903.2015.1010731..
Keywords: Asthma, Comparative Effectiveness, Patient Adherence/Compliance, Chronic Conditions