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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 25 of 34 Research Studies DisplayedFiechtner L, Perkins M, Biggs V
Comparative effectiveness of clinical and community-based approaches to healthy weight.
The objective of this study was to evaluate if two pediatric weight management interventions delivered to Hispanic, low-income children (one in a health center, the other in a Young Men's Christian Association) were effective in reducing BMI. The authors hypothesized that both would be equally effective. They were unable to establish noninferiority of the modified Healthy Weight and Your Child program. The healthy weight clinic at the health center improved BMI, offering an effective treatment of those disproportionately affected.
AHRQ-funded; HS024332.
Citation: Fiechtner L, Perkins M, Biggs V .
Comparative effectiveness of clinical and community-based approaches to healthy weight.
Pediatrics 2021 Oct;148(4). doi: 10.1542/peds.2021-050405..
Keywords: Children/Adolescents, Obesity: Weight Management, Obesity, Comparative Effectiveness, Evidence-Based Practice
Tignanelli CJ, Bramante CT, Dutta NT
Metabolic surgery may protect against admission for COVID-19 in persons with nonalcoholic fatty liver disease.
SARS-CoV-2 (COVID-19) disease causes significant morbidity and mortality through increased inflammation and thrombosis. Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are states of chronic inflammation and indicate advanced metabolic disease. The purpose of this observational study was to characterize the risk of hospitalization for COVID-19 in patients with NAFLD/NASH and evaluate the mitigating effect of various metabolic treatments.
AHRQ-funded; HS026379.
Citation: Tignanelli CJ, Bramante CT, Dutta NT .
Metabolic surgery may protect against admission for COVID-19 in persons with nonalcoholic fatty liver disease.
Surg Obes Relat Dis 2021 Oct;17(10):1780-86. doi: 10.1016/j.soard.2021.05.029..
Keywords: COVID-19, Surgery, Obesity: Weight Management, Obesity
Darling KE, Rancourt D, Evans EW
Adolescent weight management intervention in a nonclinical setting: changes in eating-related cognitions and depressive symptoms.
The present study was a secondary data analysis of a randomized controlled trial (RCT) to examine changes in depressive symptoms and eating-related cognitions in teens who participated in a non-clinic-based adolescent behavioral weight control treatment delivered by YMCA coaches. The results demonstrated some positive and no detrimental effects of a non-clinic-based behavioral weight control intervention on adolescents' eating-related cognitions and depressive symptoms.
AHRQ-funded; HS027071.
Citation: Darling KE, Rancourt D, Evans EW .
Adolescent weight management intervention in a nonclinical setting: changes in eating-related cognitions and depressive symptoms.
J Dev Behav Pediatr 2021 Sep 1;42(7):579-87. doi: 10.1097/dbp.0000000000000929..
Keywords: Children/Adolescents, Obesity: Weight Management, Obesity, Depression, Behavioral Health
Fiechtner L, Castro Cheng, ER
Characteristics of achieving clinically important weight loss in two paediatric weight management interventions.
The purpose of this study was to examine characteristics and lifestyle behaviors associated with achieving clinically important weight loss (CIWL) in two pediatric weight management interventions (PWMIs). Findings showed that, in this analysis of children enrolled in PWMIs, achieving CIWL was associated with younger age, not having severe obesity, and consuming fewer sugary beverages at the end of the intervention.
AHRQ-funded; HS024332; HS022986.
Citation: Fiechtner L, Castro Cheng, ER .
Characteristics of achieving clinically important weight loss in two paediatric weight management interventions.
Pediatr Obes 2021 Sep;16(9):e12784. doi: 10.1111/ijpo.12784..
Keywords: Children/Adolescents, Obesity: Weight Management, Obesity, Lifestyle Changes
Borgatti AC, Schneider-Worthington CR, Stager LM
The COVID-19 pandemic and weight management: effective behaviors and pandemic-specific risk factors.
This study evaluated weight management efforts among weight loss program participants during the COVID-19 pandemic. Findings showed that most online survey participants reported gaining weight during COVID-19. Further, loneliness and working remotely increased the difficulty of weight management behaviors. However, staying active, planning and tracking food consumption, choosing healthy foods, and reducing emotional eating protected against weight gain during this time.
AHRQ-funded; HS013852.
Citation: Borgatti AC, Schneider-Worthington CR, Stager LM .
The COVID-19 pandemic and weight management: effective behaviors and pandemic-specific risk factors.
Obes Res Clin Pract 2021 Sep-Oct;15(5):518-21. doi: 10.1016/j.orcp.2021.06.007..
Keywords: COVID-19, Obesity, Obesity: Weight Management, Risk
Nederveld A, Phimphasone-Brady P, Connelly L
The joys and challenges of delivering obesity care: a qualitative study of US primary care practices.
The authors sought to explore the experience of providing obesity management among primary care clinicians and their team members involved with weight loss in primary care practices. They identified three primary themes: (1) clinicians and staff involved in obesity management in primary care believe that addressing obesity is an essential part of primary care services, (2) because providing obesity care can be challenging, many practices opt out of treatment, and (3) despite the challenges, many clinicians and others find treating obesity feasible, satisfying, and worthwhile. The authors concluded that, in order to improve the ability of clinicians and practice members to treat obesity, important changes in payment, education, and work processes are necessary.
AHRQ-funded; HS024943.
Citation: Nederveld A, Phimphasone-Brady P, Connelly L .
The joys and challenges of delivering obesity care: a qualitative study of US primary care practices.
J Gen Intern Med 2021 Sep;36(9):2709-16. doi: 10.1007/s11606-020-06548-w..
Keywords: Obesity, Obesity: Weight Management, Primary Care, Medicare
Joseph CLM, Alexander GL, Lu M
Pilot study of a brief provider and EMR-based intervention for overweight teens with asthma.
The authors piloted an electronic medical record-based tailored discussion guide (TDG) and a brief provider training to address weight management in overweight teens with asthma. They observed modest improvements in patient-reported asthma outcomes and health behaviors. They found strong evidence that the TDG supports provider discussion of weight and asthma to create a more patient-centered conversation from the perspective of participating teens. They recommended addressing challenges to recruitment and clinic adaptation prior to advancing to a full-scale trial.
AHRQ-funded; HS022417.
Citation: Joseph CLM, Alexander GL, Lu M .
Pilot study of a brief provider and EMR-based intervention for overweight teens with asthma.
Pilot Feasibility Stud 2021 Aug 30;7(1):167. doi: 10.1186/s40814-021-00848-6..
Keywords: Children/Adolescents, Obesity: Weight Management, Obesity, Asthma, Chronic Conditions, Respiratory Conditions, Electronic Health Records (EHRs), Health Information Technology (HIT)
Yuce TK, Holmstrom A, Soper NJ
Complications and readmissions associated with first assistant training level following elective bariatric surgery.
Little is known regarding the variation in training level and potential clinical impact of the first assistant in bariatric surgery. In this study, the investigators described the postoperative 30-day complications and readmissions following elective bariatric procedures by training level of the first assistant. The investigators concluded that variation in training level of the first assist during bariatric surgery had no influence on DSM or readmissions.
AHRQ-funded; HS000078.
Citation: Yuce TK, Holmstrom A, Soper NJ .
Complications and readmissions associated with first assistant training level following elective bariatric surgery.
J Gastrointest Surg 2021 Aug;25(8):1948-54. doi: 10.1007/s11605-020-04787-0..
Keywords: Obesity: Weight Management, Obesity, Surgery, Hospital Readmissions, Adverse Events
Chhabra KR, Fan Z, Chao GF
The role of commercial health insurance characteristics in bariatric surgery utilization.
The goal of this study was to understand relationships among insurance plan type, out-of-pocket cost sharing, and the utilization of bariatric surgery among commercially insured patients. Over 73,000 commercially insured members of the IBM MarketScan commercial claims database who underwent bariatric surgery from 2014-17 were retroactively reviewed. Findings showed that insurance plan types with higher cost sharing have lower utilization of bariatric surgery.
AHRQ-funded; HS025778; HS000053.
Citation: Chhabra KR, Fan Z, Chao GF .
The role of commercial health insurance characteristics in bariatric surgery utilization.
Ann Surg 2021 Jun;273(6):1150-56. doi: 10.1097/sla.0000000000003569..
Keywords: Health Insurance, Obesity, Obesity: Weight Management, Surgery, Healthcare Costs, Healthcare Utilization
Shipe ME, Beeghly-Fadiel A, Deppen SA
Modeling the impact of delaying bariatric surgery due to COVID-19: a decision analysis.
In this study, the investigators developed a decision analysis model to evaluate risks and benefits of delaying scheduled bariatric surgery during the novel coronavirus disease (COVID-19) pandemic. Their base case was a 45-year-old female with diabetes and a body mass index of 45 kg/m(2). They compared immediate with delayed surgery after 6 months to allow for COVID-19 prevalence to decrease. The investigators found that immediate and delayed bariatric surgeries after 6 months resulted in similar 20-year overall survival.
AHRQ-funded; HS026122.
Citation: Shipe ME, Beeghly-Fadiel A, Deppen SA .
Modeling the impact of delaying bariatric surgery due to COVID-19: a decision analysis.
Obes Surg 2021 Mar;31(3):1387-91. doi: 10.1007/s11695-020-05054-6..
Keywords: Obesity: Weight Management, Obesity, COVID-19, Surgery, Decision Making
Gowey MA, Neumeier WH, Henry S
Executive function in individuals with clinically significant weight loss via behavioral intervention.
Researchers sought to characterize executive function (EF) in individuals who achieved clinically significant weight loss via behavioral intervention and to examine potential differences in EF between those who maintained versus regained lost weight. The study sample consisted primarily of women over age 50 with obesity; approximately half self-identified as African-American. The researchers found that most individuals with obesity who achieved clinically significant weight loss via behavioral intervention had average to above average EF; individuals who maintained their lost weight performed better on tests of decision-making.
AHRQ-funded; HS023009.
Citation: Gowey MA, Neumeier WH, Henry S .
Executive function in individuals with clinically significant weight loss via behavioral intervention.
Obes Sci Pract 2021 Feb;7(1):25-34. doi: 10.1002/osp4.458..
Keywords: Obesity: Weight Management, Obesity, Lifestyle Changes
Berge JM, Truesdale KP, Sherwood NE
Beyond the dinner table: who's having breakfast, lunch and dinner family meals and which meals are associated with better diet quality and BMI in pre-school children?.
This study examined the frequency of eating breakfast, lunch or dinner family meals and associations with pre-school children's overall diet quality and BMI percentile. The authors concluded that breakfast family meal frequency and total weekly family meal frequency were associated with healthier diet quality in non-Hispanic pre-school children but not in Hispanic children. Longitudinal research is needed to clarify the association between family meal type and child diet quality and BMI percentile.
AHRQ-funded; HS022990.
Citation: Berge JM, Truesdale KP, Sherwood NE .
Beyond the dinner table: who's having breakfast, lunch and dinner family meals and which meals are associated with better diet quality and BMI in pre-school children?.
Public Health Nutr 2017 Dec;20(18):3275-84. doi: 10.1017/s1368980017002348..
Keywords: Children/Adolescents, Family Health and History, Nutrition, Obesity: Weight Management, Racial and Ethnic Minorities
Robinson A, Fiechtner L, Roche B
Association of maternal gestational weight gain with the infant fecal microbiota.
The researchers aimed to examine associations of maternal gestational weight gain with infant fecal microbiota composition, bacterial community richness, and Shannon diversity index. Their prospective cohort study of healthy infants concluded that maternal gestational weight gain was associated with the infant fecal microbiota profiles, bacterial community richness, and Shannon diversity index.
AHRQ-funded; HS022986.
Citation: Robinson A, Fiechtner L, Roche B .
Association of maternal gestational weight gain with the infant fecal microbiota.
J Pediatr Gastroenterol Nutr 2017 Nov;65(5):509-15. doi: 10.1097/mpg.0000000000001566.
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Keywords: Maternal Care, Pregnancy, Obesity: Weight Management
Varban OA, Cassidy RB, Bonham A
Factors associated with achieving a body mass index of less than 30 after bariatric surgery.
This study identified predictors for achieving a BMI of less than 30 after bariatric surgery. Patients who had a sleeve gastrectomy, gastric bypass, or duodenal switch were more likely to achieve a BMI of less than 30 compared with those who underwent adjustable gastric banding. Only 8.5 percent of patients with a BMI greater than 50 achieved a BMI of less than 30 after bariatric surgery.
AHRQ-funded; HS023621.
Citation: Varban OA, Cassidy RB, Bonham A .
Factors associated with achieving a body mass index of less than 30 after bariatric surgery.
JAMA Surg 2017 Nov;152(11):1058-64. doi: 10.1001/jamasurg.2017.2348.
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Keywords: Health Status, Obesity, Outcomes, Obesity: Weight Management
Halbert CH, Jefferson M, Melvin CL
Provider advice about weight loss in a primary care sample of obese and overweight patients.
In this study the investigators examined receipt of provider advice to lose weight among primary care patients who were overweight and obese. The investigators found that patient beliefs about their weight status and perceptions about shared decision-making are important to receiving provider advice about weight loss/management among primary care patients.
AHRQ-funded; HS023047.
Citation: Halbert CH, Jefferson M, Melvin CL .
Provider advice about weight loss in a primary care sample of obese and overweight patients.
J Prim Care Community Health 2017 Oct;8(4):239-46. doi: 10.1177/2150131917715336..
Keywords: Decision Making, Obesity, Obesity: Weight Management, Practice Patterns, Primary Care
Pellegrini CA, Song J, Semanik PA
Patients less likely to lose weight following a knee replacement: results from the osteoarthritis initiative.
The purpose of this study was to examine weight change patterns preoperatively and postoperatively among overweight/obese knee replacement patients. Overweight and obese patients initially lost weight during the interval including knee replacement; however, they were less likely to lose more than 2.5% of their weight in the 1 to 2 years immediately after the surgery.
AHRQ-funded; HS023011.
Citation: Pellegrini CA, Song J, Semanik PA .
Patients less likely to lose weight following a knee replacement: results from the osteoarthritis initiative.
J Clin Rheumatol 2017 Oct;23(7):355-60. doi: 10.1097/rhu.0000000000000579..
Keywords: Obesity: Weight Management, Arthritis, Patient-Centered Outcomes Research, Surgery
Pellegrini CA, Ledford G, Hoffman SA
Preferences and motivation for weight loss among knee replacement patients: implications for a patient-centered weight loss intervention.
The purpose of this study was to identify knee replacement patient preferences for weight loss programs and qualitatively understand previous motives for weight loss attempts as well as strategies used to facilitate behavior changes. It provides a preliminary examination into the motives for weight loss, strategies utilized during past weight loss attempts, and preferences for future weight loss programs as described by knee replacement patients.
AHRQ-funded; HS023011.
Citation: Pellegrini CA, Ledford G, Hoffman SA .
Preferences and motivation for weight loss among knee replacement patients: implications for a patient-centered weight loss intervention.
BMC Musculoskelet Disord 2017 Aug 1;18(1):327. doi: 10.1186/s12891-017-1687-x.
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Keywords: Patient-Centered Healthcare, Surgery, Obesity, Obesity: Weight Management
Lv N, Azar KMJ, Rosas LG
Behavioral lifestyle interventions for moderate and severe obesity: a systematic review.
This study reviews evidence of behavioral lifestyle interventions for weight loss in this population. Evidence for the effectiveness of behavioral interventions versus pharmacological or surgical treatment was limited. Comprehensive and intensive behavioral interventions can result in clinically significant, albeit modest, weight loss in this obese subpopulation but may not result in significant improvements in other cardiometabolic risk factors.
AHRQ-funded; HS022702.
Citation: Lv N, Azar KMJ, Rosas LG .
Behavioral lifestyle interventions for moderate and severe obesity: a systematic review.
Prev Med 2017 Jul;100:180-93. doi: 10.1016/j.ypmed.2017.04.022.
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Keywords: Behavioral Health, Lifestyle Changes, Obesity, Obesity: Weight Management
Bossick AS, Barone C, Alexander GL
Teen, parent, and clinician expectations about obesity and related conditions during the annual well-child visit.
This study examined family (patient and parent/guardian) and clinician preferences for identification and management of obesity and obesity-related conditions during the well-child visit. Teens and parents expect weight to be discussed at well-child visits, and prefer discussions to come from a trusted clinician who uses serious, consistent language. Providers recognize several challenges and barriers to discussing weight management in the well-child visit.
AHRQ-funded; HS022417.
Citation: Bossick AS, Barone C, Alexander GL .
Teen, parent, and clinician expectations about obesity and related conditions during the annual well-child visit.
J Patient Cent Res Rev 2017 Summer;4(3):114-24. doi: 10.17294/2330-0698.1444.
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Keywords: Children/Adolescents, Clinician-Patient Communication, Obesity, Obesity: Weight Management, Patient-Centered Healthcare
Aschbrenner KA, Mueser KT, Naslund JA
Facilitating partner support for lifestyle change among adults with serious mental illness: a feasibility pilot study.
The purpose of this pilot study was to explore the feasibility of an intervention designed to facilitate partner support for lifestyle change among overweight and obese adults with serious mental illness. After 12 weeks, approximately two-thirds of participants were below their baseline weight at follow-up, including 27 percent who achieved clinically significant weight loss.
AHRQ-funded; HS021695.
Citation: Aschbrenner KA, Mueser KT, Naslund JA .
Facilitating partner support for lifestyle change among adults with serious mental illness: a feasibility pilot study.
Community Ment Health J 2017 May;53(4):394-404. doi: 10.1007/s10597-017-0100-4.
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Keywords: Family Health and History, Lifestyle Changes, Behavioral Health, Obesity, Obesity: Weight Management
Biener A, Cawley J, Meyerhoefer C
AHRQ Author: Biener A
The high and rising costs of obesity to the US health care system.
The purpose of this editorial is to provide new information on the medical care costs of obesity that help motivate various weight loss interventions. The editorial is a part of a special issue with articles examining behavioral, pharmacotherapy, and surgical interventions for weight loss, based on a 2016 conference on state-of-the-art weight management hosted by the Veterans Health Administration.
AHRQ-authored.
Citation: Biener A, Cawley J, Meyerhoefer C .
The high and rising costs of obesity to the US health care system.
J Gen Intern Med 2017 Apr;32(Suppl 1):6-8. doi: 10.1007/s11606-016-3968-8.
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Keywords: Obesity, Healthcare Costs, Obesity: Weight Management, Lifestyle Changes, Nutrition
Turer CB, Barlow SE, Montano S
Discrepancies in communication versus documentation of weight-management benchmarks: analysis of recorded visits with Latino children and associated health-record documentation.
To examine gaps in communication versus documentation of weight-management clinical practices, communication was recorded during primary care visits with 6- to 12-year-old overweight/obese Latino children. The researchers found that benchmarks were neither communicated nor documented in up to 42 percent of visits, and communicated but not documented or documented but not communicated in up to 20 percent of visits.
AHRQ-funded; HS022418.
Citation: Turer CB, Barlow SE, Montano S .
Discrepancies in communication versus documentation of weight-management benchmarks: analysis of recorded visits with Latino children and associated health-record documentation.
Glob Pediatr Health 2017 Feb 6;4:2333794x16685190. doi: 10.1177/2333794x16685190.
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Keywords: Children/Adolescents, Communication, Obesity, Primary Care, Obesity: Weight Management
Aschbrenner KA, Naslund JA, Bartels SJ
A mixed methods study of peer-to-peer support in a group-based lifestyle intervention for adults with serious mental illness.
The authors explored peer-to-peer support among individuals participating in a group lifestyle intervention that included social media to enhance in-person weight management sessions. They found that participants described how shared learning and group problem-solving activities fostered friendships and provided essential support for health behavior change, while sharing information, personal successes and challenges, and "being in the same boat" as other group members were key features of peer-to-peer support.
AHRQ-funded; HS021695.
Citation: Aschbrenner KA, Naslund JA, Bartels SJ .
A mixed methods study of peer-to-peer support in a group-based lifestyle intervention for adults with serious mental illness.
Psychiatr Rehabil J 2016 Dec;39(4):328-34. doi: 10.1037/prj0000219.
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Keywords: Lifestyle Changes, Lifestyle Changes, Behavioral Health, Obesity: Weight Management
Varban OA, Greenberg CC, Schram J
Surgical skill in bariatric surgery: Does skill in one procedure predict outcomes for another?
Whether skill for one bariatric procedure can predict outcomes for another related procedure is unknown. This study found that video ratings of surgical skill with laparoscopic gastric bypass do not predict outcomes of laparoscopic sleeve gastrectomy. Evaluation of surgical skill with one procedure may not apply to other related procedures and may require independent assessment of surgical technical proficiency.
AHRQ-funded; R01 HS023597.
Citation: Varban OA, Greenberg CC, Schram J .
Surgical skill in bariatric surgery: Does skill in one procedure predict outcomes for another?
Surgery 2016 Nov;160(5):1172-81. doi: 10.1016/j.surg.2016.04.033.
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Keywords: Surgery, Obesity: Weight Management, Obesity, Outcomes, Provider Performance
Herrin M, Tate JP, Akgun KM
Weight gain and incident diabetes among HIV-infected veterans initiating antiretroviral therapy compared with uninfected individuals.
The authors used data from the Veterans Aging Cohort Study to determine whether weight gain after antiretroviral therapy has a similar association with incident type 2 diabetes mellitus as weight gained among HIV-uninfected individuals. They found that weight gained during the first year after antiretroviral therapy initiation is associated with greater risk of diabetes mellitus than that among uninfected individuals.
AHRQ-funded; HS018372.
Citation: Herrin M, Tate JP, Akgun KM .
Weight gain and incident diabetes among HIV-infected veterans initiating antiretroviral therapy compared with uninfected individuals.
J Acquir Immune Defic Syndr 2016 Oct 1;73(2):228-36. doi: 10.1097/qai.0000000000001071.
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Keywords: Diabetes, Human Immunodeficiency Virus (HIV), Medication, Obesity: Weight Management