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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
Results1 to 5 of 5 Research Studies Displayed
Cheng TL, Mistry KB, Wang G
AHRQ Author: Mistry KB
Folate nutrition status in mothers of the Boston birth cohort, sample of a US urban low-income population.
Researchers examined maternal folic acid supplementation and plasma folate concentrations in the Boston Birth Cohort, a predominantly urban, low-income, minority population. Their findings indicated that fewer than 5 percent of mothers in the Boston Birth Cohort started folic acid supplements before pregnancy, and approximately one third of mothers had either too low or too high plasma folate levels.
Citation: Cheng TL, Mistry KB, Wang G . Folate nutrition status in mothers of the Boston birth cohort, sample of a US urban low-income population. Am J Public Health 2018 Jun;108(6):799-807. doi: 10.2105/ajph.2018.304355.
Keywords: Nutrition, Pregnancy, Low-Income, Urban Health, Vitamins and Supplements
Rizvi RF, Adam TJ, Lindemann EA
Comparing existing resources to represent dietary supplements.
Dietary supplements (DS) are widely consumed despite limited knowledge around their safety/efficacy and any well-established regulatory policies. In this pilot study, five DS resources were evaluated and compared both quantitatively and qualitatively. The authors found fragmented and inconsistent distribution of DS representation in terms of essential data elements across five resources.
Citation: Rizvi RF, Adam TJ, Lindemann EA . Comparing existing resources to represent dietary supplements. AMIA Jt Summits Transl Sci Proc 2018 May 18;2017:207-16..
Keywords: Comparative Effectiveness, Nutrition, Patient Safety, Vitamins and Supplements
Spatz ES, Wang Y, Beckman AL
Traditional Chinese medicine for acute myocardial infarction in western medicine hospitals in China.
This study examined the use of traditional Chinese medicine (TCM) in patients admitted for acute myocardial infarction (AMI) in China during the first 24 hours of hospitalization. The data came from the China Patient-centered Evaluative Assessment of Cardiac Events Retrospective Study of Acute Myocardial Infarction. A chart review was done of randomly sampled patients in 2001, 2006 and 2011 in 162 Western medicine hospitals across China. Nearly all (99%) hospitals used some form of TCM, with Salvia miltiorrhiza being the most commonly prescribed. This TCM treatment (and others) was used intravenously and use has increased over the span of the study, despite lack of evidence of benefit or harm.
Citation: Spatz ES, Wang Y, Beckman AL . Traditional Chinese medicine for acute myocardial infarction in western medicine hospitals in China. Circ Cardiovasc Qual Outcomes 2018 Mar;11(3):e004190. doi: 10.1161/circoutcomes.117.004190..
Keywords: Adverse Events, Cardiovascular Conditions, Complementary and Alternative Medicine, Heart Disease and Health, Hospitals, Mortality, Outcomes, Patient-Centered Outcomes Research, Patient Safety, Practice Patterns, Risk, Vitamins and Supplements
Butler M, Nelson VA, Davila H
Over-the-counter supplement interventions to prevent cognitive decline, mild cognitive impairment, and clinical Alzheimer-type dementia: a systematic review.
This review summarizes the evidence on efficacy and harms of over-the-counter (OTC) supplements to prevent or delay cognitive decline, mild cognitive impairment (MCI), or clinical Alzheimer-type dementia in adults with normal cognition or MCI but no dementia diagnosis. It concluded that evidence is insufficient to recommend any OTC supplement for cognitive protection in adults with normal cognition or MCI.
Citation: Butler M, Nelson VA, Davila H . Over-the-counter supplement interventions to prevent cognitive decline, mild cognitive impairment, and clinical Alzheimer-type dementia: a systematic review. Ann Intern Med 2018 Jan 2;168(1):52-62. doi: 10.7326/m17-1530.
Keywords: Comparative Effectiveness, Dementia, Patient-Centered Outcomes Research, Prevention, Vitamins and Supplements
Chilukuri N, Cheng TL, Psoter KJ
AHRQ Author: Mistry KB
Effectiveness of a pediatric primary care intervention to increase maternal folate use: results from a cluster randomized controlled trial.
This study assessed the impact of provision of folate vitamins and a preconception health intervention on folate use among a group of mostly African-American and low-income mothers bringing infants to pediatric primary care. It found that among all participants, daily vitamin intake increased from baseline to 6-month follow-up (33.8 percent vs 42.6 percent).
Citation: Chilukuri N, Cheng TL, Psoter KJ . Effectiveness of a pediatric primary care intervention to increase maternal folate use: results from a cluster randomized controlled trial. J Pediatr 2018 Jan;192:247-52.e1. doi: 10.1016/j.jpeds.2017.09.020.
Keywords: Maternal Care, Patient Adherence/Compliance, Social Determinants of Health, Primary Care, Vitamins and Supplements