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Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Drug Events (ADE) (1)
- Adverse Events (2)
- Behavioral Health (1)
- Brain Injury (1)
- Cardiovascular Conditions (2)
- (-) Children/Adolescents (17)
- Critical Care (1)
- Diagnostic Safety and Quality (1)
- Emergency Department (2)
- (-) Healthcare Cost and Utilization Project (HCUP) (17)
- Healthcare Costs (3)
- Hospital Discharge (1)
- Hospitalization (8)
- Hospital Readmissions (4)
- Hospitals (4)
- Injuries and Wounds (1)
- Inpatient Care (2)
- Medical Errors (1)
- Neurological Disorders (2)
- Newborns/Infants (1)
- Patient-Centered Outcomes Research (2)
- Patient Safety (1)
- Pneumonia (1)
- Practice Patterns (1)
- Respiratory Conditions (1)
- Risk (2)
- Sickle Cell Disease (1)
- Skin Conditions (2)
- Stroke (1)
- Surgery (1)
- Trauma (3)
- Vaccination (1)
- Young Adults (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 17 of 17 Research Studies DisplayedNguyen DK, Friedlander S, Fleischman RJ
Length of stay and complications associated with febrile infants <90 days of age hospitalized in the United States, 2000-2012.
This study tracked length of stay (LOS) and complications associated with febrile infants younger than 90 days hospitalized in the United States from 2000-2012. Data from the HCUP Kids’ Inpatient Database and other state-specific data was used to identify infants hospitalized in 2000, 2003, 2006, 2009, and 2012. Multivariate analysis was used to determine LOS, risk factors for prolonged LOS, and complications of care among infants with isolated fever or viral respiratory disease. 44,875 infants were identified with approximately two-thirds staying for 2 days or less, and 11% for 4 days or more. Factors associated with longer LOS included younger age, critical clinical status, concomitant chronic disease, and presence of complications.
AHRQ-funded; HS024146.
Citation: Nguyen DK, Friedlander S, Fleischman RJ .
Length of stay and complications associated with febrile infants <90 days of age hospitalized in the United States, 2000-2012.
Hosp Pediatr 2018 Dec;8(12):746-52. doi: 10.1542/hpeds.2018-0132..
Keywords: Healthcare Cost and Utilization Project (HCUP), Hospitalization, Newborns/Infants, Children/Adolescents
Williams CN, Piantino J, McEvoy C
The burden of pediatric neurocritical care in the United States.
This article attempts to quantify the burden of pediatric neurocritical care (PNCC) by developing national estimates of disease incidence, evaluating use of critical care interventions (CCI), and examining hospital outcomes. The Kids Inpatient Database (KID) was analyzed to evaluate cohorts with the following conditions: traumatic brain injury, neuro-infection, or inflammatory diseases; status epilepticus; stroke; hypoxic ischemic injury after cardiac arrest; or spinal cord injury.
AHRQ-funded; HS022981.
Citation: Williams CN, Piantino J, McEvoy C .
The burden of pediatric neurocritical care in the United States.
Pediatr Neurol 2018 Dec;89:31-38. doi: 10.1016/j.pediatrneurol.2018.07.013..
Keywords: Children/Adolescents, Critical Care, Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Neurological Disorders, Stroke, Trauma
Kwa MC, Silverberg JI, Ardalan K
Inpatient burden of juvenile dermatomyositis among children in the United States.
The purpose of this study was to determine the prevalence and risk factors for hospitalization with juvenile dermatomyositis and assess inpatient burden of juvenile dermatomyositis (JDM). The study authors found that JDM contributes to both increased length of hospitalization and inpatient cost of care. Non-Medicaid government insurance was associated with higher rates of hospitalization for JDM while Hispanic and other non-white racial/ethnic groups demonstrated increased length of stay and cost of care.
AHRQ-funded; HS023011.
Citation: Kwa MC, Silverberg JI, Ardalan K .
Inpatient burden of juvenile dermatomyositis among children in the United States.
Pediatr Rheumatol Online J 2018 Nov 13;16(1):70. doi: 10.1186/s12969-018-0286-1..
Keywords: Children/Adolescents, Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Skin Conditions
Wheeler KK, Shi J, Xiang H
US pediatric trauma patient unplanned 30-day readmissions.
This study sought to determine readmission rates and risk factors for acutely injured pediatric trauma patients. The study found that overall, the readmission rate for pediatric trauma patients was low. Measures of injury severity, specifically length of stay, were most useful in identifying those who would benefit from targeted care coordination resources.
AHRQ-funded; HS024263.
Citation: Wheeler KK, Shi J, Xiang H .
US pediatric trauma patient unplanned 30-day readmissions.
J Pediatr Surg 2018 Apr;53(4):765-70. doi: 10.1016/j.jpedsurg.2017.08.003..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Hospital Readmissions, Children/Adolescents, Trauma
Heslin KC, Owens PL, Simpson LA
AHRQ Author: Heslin KC Owens PL
Annual report on health care for children and youth in the united states: focus on 30-day unplanned inpatient readmissions, 2009 to 2014.
The authors describe trends in unplanned 30-day all-condition hospital readmissions for children aged 1 to 17 years between 2009 and 2014. Using HCUP data, they found that the rate of readmission was essentially stable between 2009 and 2014. In 2009, the most common reason for readmission was sickle cell anemia, whereas in 2014 the most common reason was epilepsy. Pneumonia fell from the second to the sixth most common reason for readmission over this period. The authors suggest that their study provides a baseline assessment for examining trends in 30-day unplanned pediatric readmissions, an important quality metric as the provisions of the Children's Health Insurance Program Reauthorization Act and the Affordable Care Act are changed and implemented in the future.
AHRQ-authored.
Citation: Heslin KC, Owens PL, Simpson LA .
Annual report on health care for children and youth in the united states: focus on 30-day unplanned inpatient readmissions, 2009 to 2014.
Acad Pediatr 2018 Nov - Dec;18(8):857-72. doi: 10.1016/j.acap.2018.06.006..
Keywords: Healthcare Cost and Utilization Project (HCUP), Children/Adolescents, Hospital Readmissions, Hospitalization, Hospitals, Sickle Cell Disease, Pneumonia, Neurological Disorders
Egorova NN, Pincus HA, Shemesh E
Behavioral health diagnoses among children and adolescents hospitalized in the United States: observations and implications.
The study described rates and characteristics of U.S. children hospitalized with a behavioral (mental or substance use) disorder. The study concluded that nearly 500,000 pediatric admissions in 2012 included behavioral disorders. Comorbidities were associated with longer stays and an estimated $1.36 billion additional annual costs, which were disproportionately borne by public insurance.
AHRQ-funded; HS20518; HS024433.
Citation: Egorova NN, Pincus HA, Shemesh E .
Behavioral health diagnoses among children and adolescents hospitalized in the United States: observations and implications.
Psychiatr Serv 2018 Aug;69(8):910-18. doi: 10.1176/appi.ps.201700389..
Keywords: Behavioral Health, Children/Adolescents, Diagnostic Safety and Quality, Healthcare Cost and Utilization Project (HCUP)
Leyenaar JK, Shieh MS, Lagu T
Hospital and community characteristics associated with pediatric direct admission to hospital.
Researchers aimed to determine the relationships between hospital and community factors and pediatric direct admission rates, and to evaluate the degree to which these characteristics explain variation in risk-adjusted direct admission rates. Using HCUP data, they found that direct admission rates were associated with several hospital and community characteristics, but the majority of variation in hospitals' direct admission rates was not explained by these factors. They recommended that their findings suggest opportunities for diverse hospital types to develop the infrastructure and communication systems necessary to support pediatric direct admissions.
AHRQ-funded; HS024133.
Citation: Leyenaar JK, Shieh MS, Lagu T .
Hospital and community characteristics associated with pediatric direct admission to hospital.
Acad Pediatr 2018 Jul;18(5):525-34. doi: 10.1016/j.acap.2017.10.002..
Keywords: Children/Adolescents, Hospitalization, Healthcare Cost and Utilization Project (HCUP), Hospitals
Doupnik SK, Lawlor J, Zima BT
Mental health conditions and unplanned hospital readmissions in children.
Mental health conditions (MHCs) are prevalent among hospitalized children and could influence the success of hospital discharge. The objective of this retrospective cross-sectional study was to assess the relationship between MHCs and 30-day readmissions. The investigators concluded that MHCs were associated with a higher likelihood of hospital readmission in children admitted for medical conditions and procedures. They suggest that understanding the influence of MHCs on readmissions could guide strategic planning to reduce unplanned readmissions for children with co-occurring physical and mental health conditions.
AHRQ-funded; HS023292.
Citation: Doupnik SK, Lawlor J, Zima BT .
Mental health conditions and unplanned hospital readmissions in children.
J Hosp Med 2018 Jul;13(7):445-52. doi: 10.12788/jhm.2910..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Hospital Discharge, Hospital Readmissions, Hospitalization, Risk, Young Adults
Chen C, Peng J, Sribnick EA
Trend of age-adjusted rates of pediatric traumatic brain injury in U.S. emergency departments from 2006 to 2013.
The objective of this study was to use the 2006(-)2013 Nationwide Emergency Department Sample (NEDS) database to describe trends of age-adjusted rates of pediatric traumatic brain injuries (TBI) treated in U.S. emergency departments. The investigators found that the overall age-adjusted rates of pediatric TBI-related emergency department (ED) visits increased from 2006 to 2013, which was largely caused by pediatric mild TBIs, especially unspecified injury to the head (ICD-9-CM code 959.01) and concussion.
AHRQ-funded; HS024263.
Citation: Chen C, Peng J, Sribnick EA .
Trend of age-adjusted rates of pediatric traumatic brain injury in U.S. emergency departments from 2006 to 2013.
Int J Environ Res Public Health 2018 Jun 5;15(6). doi: 10.3390/ijerph15061171..
Keywords: Brain Injury, Children/Adolescents, Emergency Department, Healthcare Cost and Utilization Project (HCUP), Trauma
Sun SA, Ma X, Li G
Epidemiologic patterns of in-hospital anaphylaxis in pediatric surgical patients.
This research letter looks into epidemiologic patterns of in-hospital anaphylaxis in pediatric surgical patients. Data from the study came from the Kids’ Inpatient Database (KIDS), which is released every 3 years. The data came from the 2003, 2006, 2009 and 2012 KID data sets. Children were included if they had a surgical admission for anaphylaxis which is interpreted as an in-hospital event. Overall in-hospital mortality for all children was 0.38% but for in-hospital anaphylaxis was 2.47%. The most common reason children were in the hospital before the event was hematological and myeloproliferative disorders, with the largest percentage undergoing bone marrow transplant procedures. Although the exact cause of the reaction was not known, hypersensitivity to chemotherapeutic agents and more recent mAb treatments have been identified as reasons for the in-hospital anaphylaxis.
AHRQ-funded; HS022941.
Citation: Sun SA, Ma X, Li G .
Epidemiologic patterns of in-hospital anaphylaxis in pediatric surgical patients.
J Allergy Clin Immunol 2018 May;141(5):1904-05.e2. doi: 10.1016/j.jaci.2017.11.030..
Keywords: Adverse Events, Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Hospitals, Inpatient Care, Practice Patterns, Surgery
Silverberg JI, Kwa L, Kwa MC
Cardiovascular and cerebrovascular comorbidities of juvenile dermatomyositis in US children: an analysis of the National Inpatient Sample.
Juvenile dermatomyositis (JDM) is associated with multiple potential risk factors for cardiovascular disease, however, little is known about cardiovascular risk in JDM. This study sought to examine the association between JDM and cardiovascular risk factors and disease in US children. It concluded that there are significantly higher odds of cardiovascular and cerebrovascular comorbidities among inpatients with JDM, with adolescents, girls and racial/ethnic minorities being at highest risk.
AHRQ-funded; HS023011.
Citation: Silverberg JI, Kwa L, Kwa MC .
Cardiovascular and cerebrovascular comorbidities of juvenile dermatomyositis in US children: an analysis of the National Inpatient Sample.
Rheumatology 2018 Apr;57(4):694-702. doi: 10.1093/rheumatology/kex465..
Keywords: Cardiovascular Conditions, Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Patient-Centered Outcomes Research, Risk
Dynan L, Goudie A, Brady PW
Pediatric adverse event rates associated with inexperience in teaching hospitals: a multilevel analysis.
In this article, the investigators hypothesize that adverse event rates increase with the availability of more complex services and technologies (transplantation and pediatric open-heart surgery); increase as experience of providers decreases (July effect); and increase with residents per bed, a measure of both average provider inexperience and congestion. Using multilevel analysis, they found empirical evidence in support of their three hypotheses.
AHRQ-funded; HS023827.
Citation: Dynan L, Goudie A, Brady PW .
Pediatric adverse event rates associated with inexperience in teaching hospitals: a multilevel analysis.
J Healthc Qual 2018 Mar/Apr;40(2):69-78. doi: 10.1097/jhq.0000000000000121..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Adverse Events, Hospitals, Inpatient Care, Medical Errors, Patient Safety
Michelson KA, Hudgins JD, Monuteaux MC
Cardiac arrest survival in pediatric and general emergency departments.
Understanding whether pediatric emergency departments (EDs) have higher survival than general EDs may help identify ways to improve care for all patients with out-of-hospital cardiac arrest (OHCA). Researchers sought to determine if OHCA survival differs between pediatric and general EDs. In their nationally representative sample, survival from nontraumatic OHCA was higher in pediatric EDs than general EDs. Survival did not differ in traumatic OHCA.
AHRQ-funded; HS000063.
Citation: Michelson KA, Hudgins JD, Monuteaux MC .
Cardiac arrest survival in pediatric and general emergency departments.
Pediatrics 2018 Feb;141(2). doi: 10.1542/peds.2017-2741.
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Keywords: Cardiovascular Conditions, Emergency Department, Healthcare Cost and Utilization Project (HCUP), Patient-Centered Outcomes Research, Children/Adolescents
Hsu DY, Shinkai K, Silverberg JI
Epidemiology of eczema herpeticum in hospitalized U.S. children: analysis of a nationwide cohort.
This study used data from the Nationwide Inpatient Sample 2002-2012 to determine incidence, risk factors, comorbidities, costs, length of stay, and mortality in hospitalized children with Eczema herpeticum (EH). A higher risk was associated with younger age and non-white ethnicity (Asian in particular). However there was less frequency of hospitalization associated with lower income quartiles. The mortality incidence was 0.1%.
AHRQ-funded; HS023011.
Citation: Hsu DY, Shinkai K, Silverberg JI .
Epidemiology of eczema herpeticum in hospitalized U.S. children: analysis of a nationwide cohort.
J Invest Dermatol 2018 Feb;138(2):265-72. doi: 10.1016/j.jid.2017.08.039..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Healthcare Costs, Hospitalization, Skin Conditions
Pringle KD, Burke RM, Steiner CA
AHRQ Author: Steiner CA
Trends in rate of seizure-associated hospitalizations among children <5 years old before and after rotavirus vaccine introduction in the United Sates, 2000-2013.
Since rotavirus vaccine introduction, hospitalizations for treatment of acute gastroenteritis have decreased. Researchers assessed whether there has been an associated decrease in seizure-associated hospitalizations. Their analysis provides evidence for a decrease in seizure hospitalizations following rotavirus vaccine introduction in the United States, with the greatest impact in age groups with a high rotavirus-associated disease burden and during rotavirus infection season.
AHRQ-authored.
Citation: Pringle KD, Burke RM, Steiner CA .
Trends in rate of seizure-associated hospitalizations among children <5 years old before and after rotavirus vaccine introduction in the United Sates, 2000-2013.
J Infect Dis 2018 Jan 30;217(4):581-88. doi: 10.1093/infdis/jix589.
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Keywords: Adverse Drug Events (ADE), Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Vaccination
Goldstein E, Nguyen HH, Liu P
AHRQ Author: Steiner CA
On the relative role of different age groups during epidemics associated with respiratory syncytial virus.
This study evaluated the roles played by individuals in different age groups during respiratory syncytial virus (RSV) epidemics in the United States between 2001 and 2012, using the previously defined relative risk (RR) statistic estimated from the hospitalization data from the Healthcare Cost and Utilization Project. Its estimates suggest the prominent relative roles of children aged </=10 years (particularly among those aged 3-6 years) in propagating RSV epidemics.
AHRQ-authored.
Citation: Goldstein E, Nguyen HH, Liu P .
On the relative role of different age groups during epidemics associated with respiratory syncytial virus.
J Infect Dis 2018 Jan 4;217(2):238-44. doi: 10.1093/infdis/jix575.
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Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Respiratory Conditions
Wheeler KK, Shi J, Nordin AB
U.S. pediatric burn patient 30-day readmissions.
The objectives of the study were to determine unscheduled 30-day readmission rates for pediatric burn patients and to identify readmission reasons. The investigators used the 2013-2014 National Readmission Database to produce 30-day all-cause unscheduled readmission rates by patient and hospital characteristics.
AHRQ-funded; HS024263.
Citation: Wheeler KK, Shi J, Nordin AB .
U.S. pediatric burn patient 30-day readmissions.
J Burn Care Res 2018 Jan;39(1):73-81. doi: 10.1097/bcr.0000000000000596..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Injuries and Wounds, Children/Adolescents, Hospital Readmissions