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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
Results1 to 1 of 1 Research Studies Displayed
Kao CJ, Wurz GT, Lin YC
Repurposing ospemifene for potentiating an antigen-specific immune response.
The overall objective of the present series of preclinical studies was to evaluate the immunomodulatory activity of ospemifene in combination with a peptide cancer vaccine. The authors concluded that, taken together, ospemifene's dose response and schedule-dependent immune modulating activity offers a method of tailoring and augmenting the efficacy of previously failed antigen-specific cancer vaccines for a wide range of malignancies.
Citation: Kao CJ, Wurz GT, Lin YC . Repurposing ospemifene for potentiating an antigen-specific immune response. Menopause 2017 Apr;24(4):437-51. doi: 10.1097/gme.0000000000000776.
Keywords: Cancer: Breast Cancer, Cancer: Lung Cancer, Medication, Vaccination