Search All Research Studies
AHRQ Research Studies Date
AHRQ Research Studies
Sign up: AHRQ Research Studies Email updates
Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
Results1 to 6 of 6 Research Studies Displayed
Guglielminotti J, Li G
Exposure to general anesthesia for cesarean delivery and odds of severe postpartum depression requiring hospitalization.
This retrospective cohort study evaluated the risk of general anesthesia use in cesarean delivery versus neuraxial anesthesia on maternal mental health. Cesarean deliveries performed in New York State hospitals between 2006 and 2013 were included. Exclusion criteria included having more than 1 cesarean delivery during the study period, residing outside of New York State, and having a general anesthetic for other surgery or delivery in the year before or after the index case. The primary outcome looked at was severe postpartum depression (PPD), and secondary outcomes were suicidal ideation, anxiety disorders, and posttraumatic stress disorder (PTSD). The majority of cesareans used neuraxial anesthesia and only 8% (34,356) had general anesthesia. Severe PPD requiring hospitalization occurred in 1158 women with 60% identified during readmission. General anesthesia was found to be associated with a 54% increased odds of PPD, and a 91% increased odds of suicidal ideation or self-inflicted injury. There was insufficient evidence for increased risk of anxiety orders.
Citation: Guglielminotti J, Li G . Exposure to general anesthesia for cesarean delivery and odds of severe postpartum depression requiring hospitalization. Anesth Analg 2020 Nov;131(5):1421-29. doi: 10.1213/ane.0000000000004663..
Keywords: Labor and Delivery, Pregnancy, Women, Depression, Behavioral Health, Surgery, Risk, Hospitalization, Medication, Adverse Drug Events (ADE), Adverse Events
Ing C, Ma X, Sun M
Exposure to surgery and anesthesia in early childhood and subsequent use of attention deficit hyperactivity disorder medications.
This study examines the association between higher rates of attention deficit hyperactivity disorder (ADHD) diagnosis and exposure to surgery and anesthesia before the age of 5. Longitudinal pharmacy data for children enrolled in Texas and New York Medicaid from 1999 to 2010 were used. They examined the association between a single exposure to anesthesia before age 5 years for 1 of 4 common pediatric surgical procedures: pyloromytomy, inguinal hernia repair, circumcisions outside the perinatal period, and tonsillectomy and/or adenectomy; and persistent ADHD medication use. A total of 213,435 children were included in the study. Children with a single exposure to anesthesia were 37% more likely than unexposed children to persistently use ADHD medication.
Citation: Ing C, Ma X, Sun M . Exposure to surgery and anesthesia in early childhood and subsequent use of attention deficit hyperactivity disorder medications. Anesth Analg 2020 Sep;131(3):723-33. doi: 10.1213/ane.0000000000004619..
Keywords: Children/Adolescents, Behavioral Health, Medication, Surgery, Adverse Drug Events (ADE), Adverse Events
Ibrahim N, Alameddine M, Brennan J
New onset alcohol use disorder following bariatric surgery.
Researchers sought to characterize the patients and incidence of alcohol use disorder (AUD) following sleeve gastrectomy (SG) compared to Roux-en-Y gastric bypass (RYGB). They found that the prevalence of alcohol use disorder in patients undergoing SG and RYGB was similar pre- and postoperatively, with the majority of patients developing AUD following their second postoperative year. The authors recommended understanding the timing and incidence of AUD in order to provide appropriate counseling and treatment.
AHRQ-funded; HS023621; HS024403.
Citation: Ibrahim N, Alameddine M, Brennan J . New onset alcohol use disorder following bariatric surgery. Surg Endosc 2019 Aug;33(8):2521-30. doi: 10.1007/s00464-018-6545-x..
Keywords: Alcohol Use, Behavioral Health, Obesity, Obesity: Weight Management, Substance Abuse, Surgery
Nguyen UDT, Perneger T, Franklin PD
Improvement in mental health following total hip arthroplasty: the role of pain and function.
This prospective study examined whether mental health improved in patients who had total hip arthroplasty (THA) due to improvement in pain and function 1 year post-surgery. Patients enrolled in a THA registry from 2010 to 2014 were included and the mental component score (MCS) was examined before and 1 year post-surgery. There was a significant improvement in mental health due to less pain and improved function.
Citation: Nguyen UDT, Perneger T, Franklin PD . Improvement in mental health following total hip arthroplasty: the role of pain and function. BMC Musculoskelet Disord 2019 Jun 29;20(1):307. doi: 10.1186/s12891-019-2669-y..
Keywords: Health Status, Behavioral Health, Orthopedics, Outcomes, Pain, Patient-Centered Outcomes Research, Quality of Life, Surgery
Loucas CA, Brand SR, Bedoya SZ
Preparing youth with cancer for amputation: a systematic review.
This review aimed to examine and identify the type and degree of psychosocial preparation provided to the child with cancer and family prior to amputation. Its findings demonstrate that there is a lack of studies to date that have adequately addressed psychosocial preparation prior to amputation for pediatric oncology patients.
Citation: Loucas CA, Brand SR, Bedoya SZ . Preparing youth with cancer for amputation: a systematic review. J Psychosoc Oncol 2017 Jul-Aug;35(4):483-93. doi: 10.1080/07347332.2017.1307894.
Keywords: Cancer, Children/Adolescents, Behavioral Health, Surgery
Zanocco K, Butt Z, Kaltman D
Improvement in patient-reported physical and mental health after parathyroidectomy for primary hyperparathyroidism.
The objective of this study was to evaluate the feasibility of Patient-Reported Outcomes Measurement Information System (PROMIS) assessment in the clinical setting to measure changes in patient-reported health before and after parathyroidectomy. It found that PROMIS is an efficient clinical assessment platform for measuring patient-reported outcomes in primary hyperparathyroidism via computer-adaptive testing.
Citation: Zanocco K, Butt Z, Kaltman D . Improvement in patient-reported physical and mental health after parathyroidectomy for primary hyperparathyroidism. Surgery 2015 Sep;158(3):837-45. doi: 10.1016/j.surg.2015.03.054..
Keywords: Health Status, Surgery, Behavioral Health, Patient-Centered Outcomes Research, Outcomes