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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedBrault MA, Spiegelman D, Abdool Karim SS
Integrating and interpreting findings from the latest treatment as prevention trials.
This paper examined findings from some 2018-2019 international studies assessing the effectiveness of reducing HIV incidence by expanding HIV testing, linkage to HIV treatment, and helping persons living with HIV adhere to their medications (called the 90-90-90 strategy). A number of these “treatment as prevention” (TasP) tests had complex results. The studies examined included the TasP/ANRS 12249 study in South Africa, the SEARCH study in Kenya and Uganda, and one comparison (arms A to C) of the HPtn 071 (PopART) study in South Africa and Zambia as well as the Botswana Ya Tsie study. All but the Botswana Ya Tsie study and the second comparison (arms B to C) of PopART did not demonstrate a community impact on HIV incidence. But those two studies indicated significant (30%) reductions in HIV incidence in the intervention communities.
AHRQ-funded; HS023000.
Citation: Brault MA, Spiegelman D, Abdool Karim SS .
Integrating and interpreting findings from the latest treatment as prevention trials.
Curr HIV/AIDS Rep 2020 Jun;17(3):249-58. doi: 10.1007/s11904-020-00492-4..
Keywords: Human Immunodeficiency Virus (HIV), Prevention, Implementation, Medication, Screening