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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
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1 to 4 of 4 Research Studies Displayed
Zhou J, Hodges JS, Suri MFK
A Bayesian hierarchical model estimating CACE in meta-analysis of randomized clinical trials with noncompliance.
Noncompliance to assigned treatment is a common challenge in analysis and interpretation of randomized clinical trials. The complier average causal effect (CACE) approach provides a useful tool for addressing noncompliance, where CACE is defined as the average difference in potential outcomes for the response in the subpopulation of subjects who comply with their assigned treatments. In this article, the investigators present a Bayesian hierarchical model to estimate the CACE in a meta-analysis of randomized clinical trials where compliance may be heterogeneous between studies.
AHRQ-funded; HS024743.
Citation:
Zhou J, Hodges JS, Suri MFK .
A Bayesian hierarchical model estimating CACE in meta-analysis of randomized clinical trials with noncompliance.
Biometrics 2019 Sep;75(3):978-87. doi: 10.1111/biom.13028..
Keywords:
Patient Adherence/Compliance, Research Methodologies
Masho SW, Ihongbe TO, Wan W
Effectiveness of shortened time interval to postpartum visit in improving postpartum attendance: design and rationale for a randomized controlled trial.
Recent evidence suggests that there are numerous benefits to scheduling postpartum visits as early as 3 weeks post-delivery. However, findings are not conclusive due to methodological limitations. This report discussed the unique aspects of a randomized controlled trial's (RCT) design, intervention, and strategies to maintain participant retention. The study design offered unique features which ensured excellent participant completion and adherence rates, despite the presence of hard-to-track women who typically do not return for their postpartum visits.
AHRQ-funded; HS021504.
Citation:
Masho SW, Ihongbe TO, Wan W .
Effectiveness of shortened time interval to postpartum visit in improving postpartum attendance: design and rationale for a randomized controlled trial.
Contemp Clin Trials 2019 Jun;81:40-43. doi: 10.1016/j.cct.2019.04.012..
Keywords:
Maternal Care, Pregnancy, Women, Patient Adherence/Compliance, Research Methodologies
Kahwati L, Viswanathan M, Golin CE
Identifying configurations of behavior change techniques in effective medication adherence interventions: a qualitative comparative analysis.
The researchers aimed to extend the results from an existing systematic review of interventions to improve medication adherence by using qualitative comparative analysis (QCA) to identify necessary or sufficient configurations of behavior change techniques among effective interventions. They were able to identify seven configurations of behavior change techniques sufficient for improving adherence, which together accounted for 26 (76 percent) of the effective studies.
AHRQ-funded; HS022563.
Citation:
Kahwati L, Viswanathan M, Golin CE .
Identifying configurations of behavior change techniques in effective medication adherence interventions: a qualitative comparative analysis.
Syst Rev 2016 May 4;5:83. doi: 10.1186/s13643-016-0255-z.
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Keywords:
Medication, Patient Adherence/Compliance, Research Methodologies, Comparative Effectiveness, Behavioral Health
Kahwati L, Jacobs S, Kane H
Using qualitative comparative analysis in a systematic review of a complex intervention.
The objective of this study was to describe in detail and examine the suitability of using qualitative comparative analysis (QCA) within the context of a systematic review. It concluded that QCA was suitable for use within a systematic review of medication adherence interventions and offered insights beyond the single dimension stratifications used in the original completed review.
AHRQ-funded; HS022563.
Citation:
Kahwati L, Jacobs S, Kane H .
Using qualitative comparative analysis in a systematic review of a complex intervention.
Syst Rev 2016 May 4;5:82. doi: 10.1186/s13643-016-0256-y.
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Keywords:
Medication, Patient Adherence/Compliance, Research Methodologies, Comparative Effectiveness, Behavioral Health
