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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 4 of 4 Research Studies DisplayedSchnall R, Sanabria G, Jia R, Sanabria G, Jia H
Efficacy of an mHealth self-management intervention for persons living with HIV: the WiseApp randomized clinical trial.
This study’s objective was to determine the efficacy of WiseApp, a user-centered design mHealth intervention to improve antiretroviral therapy (ART) adherence and viral suppression in persons living with HIV (PLWH). This randomized case-control trial had two study arms: a randomized controlled efficacy trial arm (n = 99) and an attention control intervention arm (n = 101) among PLWH living in New York City. The authors found a significant improvement in ART adherence in the intervention arm compared to the attention control arm from day 1 (69.7% vs 48.3%) to day 59 (51.2% vs 37.2%) of the study period. From day 60 to 120, the intervention had higher but not statistically significant adherence rates. Secondary analyses showed no difference in change from baseline to 3 or 6 months between the 2 study arms.
AHRQ-funded; HS025071.
Citation: Schnall R, Sanabria G, Jia R, Sanabria G, Jia H .
Efficacy of an mHealth self-management intervention for persons living with HIV: the WiseApp randomized clinical trial.
J Am Med Inform Assoc 2023 Feb 16; 30(3):418-26. doi: 10.1093/jamia/ocac233..
Keywords: Telehealth, Patient Self-Management, Human Immunodeficiency Virus (HIV), Chronic Conditions, Health Information Technology (HIT)
Flynn G, Jia H, Reynolds NR
Protocol of the randomized control trial: the WiseApp trial for improving health outcomes in PLWH (WiseApp).
This paper outlines the protocol for the WiseApp randomized control trial. The WiseApp contains real-time medication monitoring linking an electronic pill bottle and fitness tracker to the app, helping persons living with HIV (PLWH) self-manage their medication adherence and improve their overall quality of life. The primary objective of the trial is to test the effect of the WiseApp's medication adherence features on antiretroviral adherence in underserved PLWH in New York City. The real-time monitoring of the WiseApp has the potential to help providers initiate interventions to help patients resume treatment before drug resistance begins.
AHRQ-funded; HS025071.
Citation: Flynn G, Jia H, Reynolds NR .
Protocol of the randomized control trial: the WiseApp trial for improving health outcomes in PLWH (WiseApp).
BMC Public Health 2020 Nov 25;20(1):1775. doi: 10.1186/s12889-020-09688-0..
Keywords: Human Immunodeficiency Virus (HIV), Medication, Telehealth, Health Information Technology (HIT), Patient Adherence/Compliance, Patient Self-Management, Chronic Conditions, Care Management, Healthcare Delivery
Beauchemin M, Gradilla M, Baik D
A multi-step usability evaluation of a self-management app to support medication adherence in persons living with HIV.
The authors developed a mHealth app (WiseApp) for HIV self-management to help persons living with HIV (PLWH) self-manage their health. The purpose of this study was to evaluate the usability of the WiseApp. The results of the cognitive walkthrough with both experts and end-users informed iterative refinements to the WiseApp and finalization of a mHealth app for PLWH to better self-manage their health.
AHRQ-funded; HS025071.
Citation: Beauchemin M, Gradilla M, Baik D .
A multi-step usability evaluation of a self-management app to support medication adherence in persons living with HIV.
Int J Med Inform 2019 Feb;122:37-44. doi: 10.1016/j.ijmedinf.2018.11.012..
Keywords: Health Information Technology (HIT), Human Immunodeficiency Virus (HIV), Medication, Patient Adherence/Compliance, Patient Self-Management
Cho H, Porras T, Baik D
Understanding the predisposing, enabling, and reinforcing factors influencing the use of a mobile-based HIV management app: a real-world usability evaluation.
In this study, the authors conducted an in-depth analysis of users' experiences using an HIV self-management app. Usability evaluation in a real-world setting enabled the investigators to measure users' actual experiences when interacting with the app during their everyday lives. They suggest that their work highlighted the importance of using mobile technology for persons living with HIV, specifically those with low income/housing instability.
AHRQ-funded; HS023963.
Citation: Cho H, Porras T, Baik D .
Understanding the predisposing, enabling, and reinforcing factors influencing the use of a mobile-based HIV management app: a real-world usability evaluation.
Int J Med Inform 2018 Sep;117:88-95. doi: 10.1016/j.ijmedinf.2018.06.007..
Keywords: Health Information Technology (HIT), Human Immunodeficiency Virus (HIV), Patient-Centered Outcomes Research, Patient Self-Management