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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
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1 to 3 of 3 Research Studies Displayed
Salinas JL, Rentsch C, Marconi VC
Baseline, time-updated, and cumulative HIV care metrics for predicting acute myocardial infarction and all-cause mortality.
The researchers studied prediction rates of myocardial infarction in those with HIV. They found that the Veterans Aging Cohort Study (VACS) Index provided better acute myocardial infarction and mortality prediction than CD4 count and HIV-1 RNA, concluding that current health determines risk more accurately than prior history.
AHRQ-funded; HS018372.
Citation:
Salinas JL, Rentsch C, Marconi VC .
Baseline, time-updated, and cumulative HIV care metrics for predicting acute myocardial infarction and all-cause mortality.
Clin Infect Dis 2016 Dec 1;63(11):1423-30. doi: 10.1093/cid/ciw564.
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Keywords:
Human Immunodeficiency Virus (HIV), Mortality, Heart Disease and Health, Risk
King JT, Perkal MF, Rosenthal RA
Thirty-day postoperative mortality among individuals with HIV infection receiving antiretroviral therapy and procedure-matched, uninfected comparators.
The researchers explored the current relationship between perioperative mortality and indicators of immune function, anemia, and hypoalbuminemia among HIV-infected and uninfected individuals. Among HIV-infected patients receiving antiretroviral therapy, modern postoperative mortality rates are low and lower CD4 cell counts are associated with increased mortality, but characteristics other than HIV status, such as age and hypoalbuminemia, are also important determinants of outcome.
AHRQ-funded; HS021112.
Citation:
King JT, Perkal MF, Rosenthal RA .
Thirty-day postoperative mortality among individuals with HIV infection receiving antiretroviral therapy and procedure-matched, uninfected comparators.
JAMA Surg 2015 Apr;150(4):343-51. doi: 10.1001/jamasurg.2014.2257..
Keywords:
Healthcare Cost and Utilization Project (HCUP), Mortality, Human Immunodeficiency Virus (HIV), Hospitalization, Surgery
Samji H, Cescon A, Hogg RS
Closing the gap: increases in life expectancy among treated HIV-positive individuals in the United States and Canada.
The researchers estimated changes in life expectancy among HIV-positive adults on antiretroviral therapy (ART) from 2000–2007 in the U.S. and Canada. They concluded that a 20-year-old HIV-positive adult on ART in the U.S. or Canada is expected to live into their early 70s, a life expectancy approaching that of the general population. Differences by sex, race, HIV transmission risk group, and CD4 count remain.
AHRQ-funded; 290010012.
Citation:
Samji H, Cescon A, Hogg RS .
Closing the gap: increases in life expectancy among treated HIV-positive individuals in the United States and Canada.
PLoS One 2013 Dec 18;8(12):e81355. doi: 10.1371/journal.pone.0081355..
Keywords:
Human Immunodeficiency Virus (HIV), Mortality
