Search all AHRQ sites
Menu
SHARE:
AHRQ Research Studies
Sign up: 
AHRQ Research Studies Email updates
Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 2 of 2 Research Studies DisplayedProbst MA, Gupta M, Hendey GW
Prevalence of intracranial injury in adult patients with blunt head trauma with and without anticoagulant or antiplatelet use.
In this study, the investigators determined the prevalence of significant intracranial injury among adults with blunt head trauma who are receiving preinjury anticoagulant or antiplatelet medications. The investigators concluded that patients receiving preinjury warfarin or a combination of aspirin and clopidogrel were at increased risk for significant intracranial injury, but not those receiving aspirin alone. They suggested that clinicians should have a low threshold for neuroimaging when evaluating patients receiving warfarin or a combination of aspirin and clopidogrel.
AHRQ-funded; HS009699.
Citation: Probst MA, Gupta M, Hendey GW .
Prevalence of intracranial injury in adult patients with blunt head trauma with and without anticoagulant or antiplatelet use.
Ann Emerg Med 2020 Mar;75(3):354-64. doi: 10.1016/j.annemergmed.2019.10.004..
Keywords: Brain Injury, Injuries and Wounds, Blood Thinners, Medication, Medication: Safety, Adverse Drug Events (ADE), Adverse Events, Risk
Albrecht JS, Perfetto EM, Daniel Mullins C
Safety of antidepressant classes used following traumatic brain injury among Medicare beneficiaries: a retrospective cohort study.
The objective of this study was to compare the risk of several adverse events associated with use of the three most commonly used classes of antidepressants following Traumatic Brain Injury (TBI) in older adults. One of the study’s conclusions was that compared to tricyclic antidepressants, selective serotonin reuptake inhibitor use was associated with increased risk of hemorrhagic stroke.
AHRQ-funded; HS024560
Citation: Albrecht JS, Perfetto EM, Daniel Mullins C .
Safety of antidepressant classes used following traumatic brain injury among Medicare beneficiaries: a retrospective cohort study.
Drugs Aging 2018 Aug;35(8):763-72. doi: 10.1007/s40266-018-0570-2..
Keywords: Adverse Events, Medication, Brain Injury, Elderly, Patient Safety
