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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
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1 to 4 of 4 Research Studies Displayed
Carson NJ, Progovac AM, Wang Y
A decline in depression treatment following FDA antidepressant warnings largely explains racial/ethnic disparities in prescription fills.
The Food and Drug Administration's 2004 antidepressant warning was followed by decreases in antidepressant prescribing for youth. Little is known about how antidepressant prescribing patterns varied by race/ethnicity. This study analyzed Medicaid claims data from four U.S. states (2002-2009) for youth ages 5-17. The authors found that antidepressant prescription fills declined most post-warning for White youth, suggesting that risk information may have diffused less rapidly to prescribers or caregivers of minorities.
AHRQ-funded; HS021486.
Citation:
Carson NJ, Progovac AM, Wang Y .
A decline in depression treatment following FDA antidepressant warnings largely explains racial/ethnic disparities in prescription fills.
Depress Anxiety 2017 Dec;34(12):1147-56. doi: 10.1002/da.22681..
Keywords:
Medication, Children/Adolescents, Depression, Guidelines, Racial / Ethnic Minorities
Cosgrove L, Krimsky S, Wheeler EE
Conflict of interest policies and industry relationships of guideline development group members: A cross-sectional study of clinical practice guidelines for depression.
The purpose of the present study was to assess a) the disclosure requirements of guideline development groups in a cross-section of guidelines for major depression; and, b) the extent and type of conflicts of panel members. It found that most of the guidelines were developed by panels that had members with industry financial ties to drug companies that manufacture antidepressant medication.
AHRQ-funded; HS022940.
Citation:
Cosgrove L, Krimsky S, Wheeler EE .
Conflict of interest policies and industry relationships of guideline development group members: A cross-sectional study of clinical practice guidelines for depression.
Account Res 2017;24(2):99-115. doi: 10.1080/08989621.2016.1251319.
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Keywords:
Medication, Depression, Guidelines, Behavioral Health, Research Methodologies
Cosgrove L, Shaughnessy AF, Peters SM
Conflicts of interest and the presence of methodologists on guideline development panels: a cross-sectional study of clinical practice guidelines for major depressive disorder.
The authors aimed to review treatment guidelines for major depressive disorder and assess the relationship between endorsement of antidepressants for mild depression as a first-line intervention and financial conflicts of interest of guideline panel members. They concluded that ensuring that guideline development groups are free of commercial ties and include individuals with methodological expertise provides an important safeguard – that an evidence-based review is applied at every stage, from the framing of the questions for review, to searching, evaluating, and synthesizing the evidence.
AHRQ-funded; HS022940.
Citation:
Cosgrove L, Shaughnessy AF, Peters SM .
Conflicts of interest and the presence of methodologists on guideline development panels: a cross-sectional study of clinical practice guidelines for major depressive disorder.
Psychother Psychosom 2017;86(3):168-70. doi: 10.1159/000458727.
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Keywords:
Depression, Evidence-Based Practice, Guidelines, Research Methodologies
Lewandowski RE, Acri MC, Hoagwood KE
Evidence for the management of adolescent depression.
This article reports on the development of a care pathway and quality indicators (QIs) for the primary and specialty care management of adolescent depression. It also reviews clinical practice guidelines and identifies barriers to the development of QIs, such as gaps in the empirical evidence. Finally, a research agenda is suggested.
AHRQ-funded; HS020503
Citation:
Lewandowski RE, Acri MC, Hoagwood KE .
Evidence for the management of adolescent depression.
Pediatrics. 2013 Oct;132(4):e996-e1009. doi: 10.1542/peds.2013-0600..
Keywords:
Children/Adolescents, Depression, Quality Indicators (QIs), Guidelines, Quality of Care
