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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedFeldman S, Kasjanski R, Poposki J
Chronic airway inflammation provides a unique environment for B cell activation and antibody production.
This study sought to determine the mechanisms that drive B cell activation and antibody production during chronic airway inflammation. It found that nasal polyps contained significantly elevated frequencies of plasmablasts, especially those that expressed the extrafollicular marker Epstein-Barr virus-induced protein 2 (EBI2), but significantly fewer germinal centre (GC) B cells compared with tonsil.
AHRQ-funded; HS023011.
Citation: Feldman S, Kasjanski R, Poposki J .
Chronic airway inflammation provides a unique environment for B cell activation and antibody production.
Clin Exp Allergy 2017 Apr;47(4):457-66. doi: 10.1111/cea.12878.
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Keywords: Chronic Conditions, Genetics, Respiratory Conditions