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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.

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1 to 5 of 5 Research Studies Displayed
Oates GR, Niranjan SJ, Ott C
Adherence to pulmonary rehabilitation in COPD: a qualitative exploration of patient perspectives on barriers and facilitators.
Adherence to pulmonary rehabilitation (PR) is low. This qualitative study used the PRECEDE model to identify predisposing (intrapersonal), reinforcing (interpersonal), and enabling (structural) factors acting as barriers or facilitators of adherence to PR, and elicit recommendations for solutions from patients with chronic obstructive pulmonary disease (COPD). The investigators concluded that health limitations, social support, transportation and financial difficulties, and program features impact ability of patients to attend PR.
AHRQ-funded; HS023009.
Citation: Oates GR, Niranjan SJ, Ott C . Adherence to pulmonary rehabilitation in COPD: a qualitative exploration of patient perspectives on barriers and facilitators. J Cardiopulm Rehabil Prev 2019 Sep;39(5):344-49. doi: 10.1097/hcr.0000000000000436..
View abstract on the National Library of Medicine site.
Keywords: Respiratory Conditions, Rehabilitation, Patient Adherence/Compliance, Chronic Conditions
Wei YJ, Simoni-Wastila L, Albrecht JS
The association of antidepressant treatment with COPD maintenance medication use and adherence in a comorbid Medicare population: a longitudinal cohort study.
Researchers examined the association between antidepressant treatment and use of and adherence to chronic obstructive pulmonary disease (COPD) maintenance medications among patients with new-onset COPD and comorbid depression. They concluded that regularly treated depression may increase use of and adherence to necessary maintenance medications for COPD.
AHRQ-funded; HS024560.
Citation: Wei YJ, Simoni-Wastila L, Albrecht JS . The association of antidepressant treatment with COPD maintenance medication use and adherence in a comorbid Medicare population: a longitudinal cohort study. Int J Geriatr Psychiatry 2018 Feb;33(2):e212-e20. doi: 10.1002/gps.4772.
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View abstract on the National Library of Medicine site.
Keywords: Medication, Respiratory Conditions, Elderly, Patient Adherence/Compliance
Oates GR, Hamby BW, Stepanikova I
Social determinants of adherence to pulmonary rehabilitation for chronic obstructive pulmonary disease.
Adherence to pulmonary rehabilitation (PR) is low. Previous studies have focused on clinical predictors of PR completion. This study aimed to identify social determinants of adherence to PR. The findings showed that, relative to high adherence, low adherence is associated with limited functional capacity and current smoking, while moderate adherence is associated with socioeconomic disadvantage. The distinction highlights different pathways to suboptimal adherence and calls for tailored intervention approaches.

AHRQ-funded; HS023009.
Citation: Oates GR, Hamby BW, Stepanikova I . Social determinants of adherence to pulmonary rehabilitation for chronic obstructive pulmonary disease. Copd 2017 Dec;14(6):610-17. doi: 10.1080/15412555.2017.1379070..
View abstract on the National Library of Medicine site.
Keywords: Respiratory Conditions, Racial / Ethnic Minorities, Patient Adherence/Compliance, Social Determinants of Health
Albrecht JS, Khokhar B, Huang TY
Adherence and healthcare utilization among older adults with COPD and depression.
The researchers quantified the independent effects of adherence to antidepressants and chronic obstructive pulmonary disease (COPD) maintenance medications on healthcare utilization among individuals co-diagnosed with COPD and depression. They found that, compared to no use,higher levels of adherence to COPD maintenance medications were associated with decreased risk of ED visits and hospitalizations. Similarly, higher levels of adherence to antidepressants resulted in decreased risk of ED visits and hospitalization.
AHRQ-funded; HS024560.
Citation: Albrecht JS, Khokhar B, Huang TY . Adherence and healthcare utilization among older adults with COPD and depression. Respir Med 2017 Aug;129:53-58. doi: 10.1016/j.rmed.2017.06.002.
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View abstract on the National Library of Medicine site.
Keywords: Elderly, Healthcare Utilization, Respiratory Conditions, Depression, Patient Adherence/Compliance
Albrecht JS, Park Y, Hur P
Adherence to maintenance medications among older adults with chronic obstructive pulmonary disease. the role of depression.
The objective of this study was to assess the impact of depression on COPD maintenance medication adherence among of Medicare beneficiaries newly diagnosed with COPD. Average monthly adherence to COPD maintenance medications was low, peaking at 57 percent in the month after first fill and decreasing to 35 percent within 6 months. In the adjusted regression model, depression was associated with decreased adherence to COPD maintenance medications.
AHRQ-funded; HS024560.
Citation: Albrecht JS, Park Y, Hur P . Adherence to maintenance medications among older adults with chronic obstructive pulmonary disease. the role of depression. Ann Am Thorac Soc 2016 Sep;13(9):1497-504. doi: 10.1513/AnnalsATS.201602-136OC.
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View abstract on the National Library of Medicine site.
Keywords: Respiratory Conditions, Elderly, Medication, Patient Adherence/Compliance, Depression

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