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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
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1 to 25 of 101 Research Studies Displayed
Wurcel AG, Essien UR, Ortiz C
Variation by race in antibiotics prescribed for hospitalized patients with skin and soft tissue infections.
This cohort study examined antibiotics prescribed and variations by race among hospitalized patients with skin and soft tissue infections (SSTIs). A subanalysis of multisite, cross-sectional data collected through a national survey of acute care hospital groups within Vizient, Inc. considering adult inpatients treated for SSTIs was used. Of the 1242 adult inpatients included from 91 US hospitals, 45% were female, 18% were Black, and 69% were White with a mean age of 58 years. Penicillin allergy with hives was found in 23%, 19% with rash, and 18% with unknown effects, with allergy found more frequent in Black patients (23%) versus White (18%). Adjusting for multiple factors, White inpatients were at an increased risk of cefazolin use and decreased risk of clindamycin use compared with Black inpatients. Cefazolin use with less likely to be prescribed to Black inpatients than White inpatients and they were likely to be prescribed clindamycin. Cefazolin is considered a first-line SSTI treatment with clindamycin not recommended given frequent dosing and high potential for adverse effects including Clostridioides difficile infection (CDI). Although penicillin allergy is described as more prevalent among White patients, the authors observed an increased prevalence among Black inpatients compared with White inpatients treated for SSTI.
Citation:
Wurcel AG, Essien UR, Ortiz C .
Variation by race in antibiotics prescribed for hospitalized patients with skin and soft tissue infections.
JAMA Netw Open 2021 Dec;4(12):e2140798. doi: 10.1001/jamanetworkopen.2021.40798..
Keywords:
Antibiotics, Skin Conditions, Racial / Ethnic Minorities, Practice Patterns, Medication
Hong MR, Lei D, Yousaf M
A real-world study of the longitudinal course of itch severity and frequency in adults with atopic dermatitis.
A prospective, dermatology practice-based study was performed of adults with atopic dermatitis. Using a Numeric Rating Scale (NRS), regression models were constructed to examine itch over time. In repeated-measures regression models, persistent NRS average-itch scores were associated with baseline NRS average-itch and food allergy. Persistent NRS worst-itch was associated with baseline worst-itch NRS and Medicaid insurance. Patients with atopic dermatitis had a heterogeneous longitudinal course with fluctuating and complex overlapping patterns of average- and worst-itch intensity, and frequency.
AHRQ-funded; HS023011.
Citation:
Hong MR, Lei D, Yousaf M .
A real-world study of the longitudinal course of itch severity and frequency in adults with atopic dermatitis.
Arch Dermatol Res 2022 Mar;314(2):141-49. doi: 10.1007/s00403-021-02214-1..
Keywords:
Skin Conditions
Schwartzman G, Lei D, Ahmed A
Longitudinal course and phenotypes of health-related quality of life in adults with atopic dermatitis.
The real-world course of health-related quality of life (HRQoL) in atopic dermatitis (AD) is not well established. The aim of this prospective dermatology-practice based study was to examine predictors, longitudinal course and phenotypes of HRQoL in adult patients with AD. The investigators concluded that: patients with AD had a heterogeneous longitudinal course and distinct patterns of HRQoL; many patients had fluctuating HRQoL over time; and most patients with moderate to severe disease at baseline had persistent HRQoL impairment over time.
AHRQ-funded; HS023011.
Citation:
Schwartzman G, Lei D, Ahmed A .
Longitudinal course and phenotypes of health-related quality of life in adults with atopic dermatitis.
Clin Exp Dermatol 2022 Feb;47(2):359-72. doi: 10.1111/ced.14948..
Keywords:
Skin Conditions, Quality of Life
Zhou NY, Nili A, Blackwell CK
Parent report of sleep health and attention regulation in a cross-sectional study of infants and preschool-aged children with atopic dermatitis.
Older children with atopic dermatitis (AD) suffer from poor sleep and attention problems. However, until recently, the dearth of developmentally sensitive assessment tools impeded characterization in younger children. In this study the investigators aimed to characterize sleep and attention problems in young children with AD and identify modifiable factors. The investigators concluded that more severe AD correlates with poor sleep health and attention dysregulation.
AHRQ-funded; HS023011.
Citation:
Zhou NY, Nili A, Blackwell CK .
Parent report of sleep health and attention regulation in a cross-sectional study of infants and preschool-aged children with atopic dermatitis.
Pediatr Dermatol 2022 Jan;39(1):61-68. doi: 10.1111/pde.14889..
Keywords:
Children/Adolescents, Newborns/Infants, Sleep Problems, Skin Conditions
Chovatiya R, Silverberg JI
Association of herpes zoster and chronic inflammatory skin disease in US inpatients.
The purpose of this study was to determine whether chronic inflammatory skin disease (CISD) is associated with herpes zoster (HZ). Data from the Nationwide Inpatient Sample 2002-2012 were analyzed. Findings showed that many CISDs are associated with increased hospitalization for HZ, even below the ages recommended for HZ vaccination. Recommendations included additional studies to establish CISD-specific vaccination guidelines.
AHRQ-funded; HS023011.
Citation:
Chovatiya R, Silverberg JI .
Association of herpes zoster and chronic inflammatory skin disease in US inpatients.
J Am Acad Dermatol 2021 Dec;85(6):1437-45. doi: 10.1016/j.jaad.2019.12.073..
Keywords:
Healthcare Cost and Utilization Project (HCUP), Skin Conditions, Chronic Conditions
Silverberg JI
Validity and reliability of a novel numeric rating scale to measure skin-pain in adults with atopic dermatitis.
Little is known about the measurement properties of numeric rating scales (NRS) for pain in AD. In this study, the investigators evaluated a novel NRS for skin-pain and existing NRS for average overall-pain in adults with AD. Self-administered questionnaires and skin-examination were performed in 463 AD patients (age 18-97 years) in a dermatology practice setting.
AHRQ-funded; HS023011.
Citation:
Silverberg JI .
Validity and reliability of a novel numeric rating scale to measure skin-pain in adults with atopic dermatitis.
Arch Dermatol Res 2021 Dec;313(10):855-61. doi: 10.1007/s00403-021-02185-3..
Keywords:
Skin Conditions, Pain, Quality of Life
Cheng BT, Fishbein AB, Silverberg JI
Mental health symptoms and functional impairment in children with atopic dermatitis.
This study sought to determine the prevalence and predictors of social and behavioral symptoms and functional impairment among US children with atopic dermatitis (AD). Using MEPS data 1996-2015, findings showed that AD was associated with behavioral and functional impairment, similar to psoriasis and other common chronic conditions.
AHRQ-funded; HS023011.
Citation:
Cheng BT, Fishbein AB, Silverberg JI .
Mental health symptoms and functional impairment in children with atopic dermatitis.
Dermatitis 2021 Sep-Oct;32(5):353-61. doi: 10.1097/der.0000000000000680..
Keywords:
Children/Adolescents, Skin Conditions, Chronic Conditions, Behavioral Health
Fishbein AB, Lin B, Beaumont J
Nocturnal movements in children with atopic dermatitis have a timing pattern: a case-control study.
This case-control study compared nocturnal movements in children with atopic dermatitis (AD) with a control non-AD group. The study looked at nocturnal motor activity due to itch in children age 6 to 17 years with moderate-to-severe AD. The mean age of children with AD was 11.0 plus or minus 3.2 years, and without AD 11.5 plus or minute 3.3 years with the majority (65%) male. The AD scoring scale SCORAD was used to define moderate to severe AD. A home activity monitor, actigraphy and a sleep diary for 3 to 7 nights was used to monitor nocturnal movements and sleep. Activity counts were averaged across nights. Bouts of nocturnal activity increased in children with AD versus the controls between 1 and 6 hours after sleep onset. Nocturnal scratch activity peaks at 3 hours. Although AD patients were instructed to avoid oral antihistamine during the study, 5 patients took an antihistamine on some nights. Results showed no significant difference with respect to movement in the patients that took antihistamine some nights and not others. Timing of the nocturnal scratch behavior could potentially be targeted for treatment.
AHRQ-funded; HS023011.
Citation:
Fishbein AB, Lin B, Beaumont J .
Nocturnal movements in children with atopic dermatitis have a timing pattern: a case-control study.
J Am Acad Dermatol 2021 Aug;85(2):474-76. doi: 10.1016/j.jaad.2018.04.020..
Keywords:
Children/Adolescents, Skin Conditions, Chronic Conditions
Silverberg JI, Lai Cella, D D
Reliability and meaningful change of the Patient-Reported Outcomes Measurement Information System(®) Itch Questionnaire (PIQ) item banks in adults with atopic dermatitis.
The Patient-Reported Outcomes Measurement Information System Itch Questionnaire (PIQ), includes a suite of patient-reported outcome measures to assess the burden of itch in adults. In this study, the investigators sought to determine the smallest detectable change (SDC), threshold for meaningful improvement and test–retest reliability of PIQ item banks for assessing the burden of itch in adult AD.
AHRQ-funded; HS023011.
Citation:
Silverberg JI, Lai Cella, D D .
Reliability and meaningful change of the Patient-Reported Outcomes Measurement Information System(®) Itch Questionnaire (PIQ) item banks in adults with atopic dermatitis.
Br J Dermatol 2021 Aug;185(2):438-39. doi: 10.1111/bjd.20066..
Keywords:
Skin Conditions, Patient-Centered Outcomes Research, Outcomes, Diagnostic Safety and Quality
Fishbein AB, Cheng BT, Tilley CC
Sleep disturbance in school-aged children with atopic dermatitis: prevalence and severity in a cross-sectional sample.
The authors sought to estimate the US prevalence of sleep disturbance and its impact on psychological and neurocognitive function in patients with atopic dermatitis (AD). Using PROMIS (Patient Reported Outcome Measurement Information System), they found that sleep disturbance was a common symptom of AD affecting approximately 3 million US children and was associated with neuropsychiatric impairment, including depression, anxiety, and inattention. They recommended that clinicians screen for these symptoms in school-aged children, particularly with moderate-to-severe AD.
AHRQ-funded; HS023011.
Citation:
Fishbein AB, Cheng BT, Tilley CC .
Sleep disturbance in school-aged children with atopic dermatitis: prevalence and severity in a cross-sectional sample.
J Allergy Clin Immunol Pract 2021 Aug;8(8):3120-29.e3. doi: 10.1016/j.jaip.2021.04.064..
Keywords:
Children/Adolescents, Sleep Problems, Skin Conditions
Lee S, Rastogi S, Hsu DY
Association of bullous pemphigoid and comorbid health conditions: a case-control study.
Bullous pemphigoid is an autoimmune skin disease characterized by the formation of blisters between the epidermis and dermis. Comorbidities of pemphigoid have not been well-described. Identification of comorbidities associated with pemphigoid is important to decrease morbidity and mortality. The purpose of the study was to identify the comorbid health conditions of bullous pemphigoid. The investigators concluded bullous pemphigoid patients needed screening for comorbid health conditions even though treatment options did not seem to be associated with these comorbidities.
AHRQ-funded; HS023011.
Citation:
Lee S, Rastogi S, Hsu DY .
Association of bullous pemphigoid and comorbid health conditions: a case-control study.
Arch Dermatol Res 2021 Jul;313(5):327-32. doi: 10.1007/s00403-020-02100-2..
Keywords:
Skin Conditions, Chronic Conditions
Chovatiya R, Lei D, Ahmed A
Clinical phenotyping of atopic dermatitis using combined itch and lesional severity: a prospective observational study.
The purpose of this study was to determine the characteristics, associations, burden, and course of patients with atopic dermatitis (AD) using combined itch and lesional severity. Findings showed that combined itch and lesional severity seem to describe unique AD phenotypes. Recommendations included further studies to confirm these findings and to understand the optimal treatments for these groups.
AHRQ-funded; HS023011.
Citation:
Chovatiya R, Lei D, Ahmed A .
Clinical phenotyping of atopic dermatitis using combined itch and lesional severity: a prospective observational study.
Ann Allergy Asthma Immunol 2021 Jul;127(1):83-90.e2. doi: 10.1016/j.anai.2021.03.019..
Keywords:
Skin Conditions, Chronic Conditions
Herb JN, Ollila DW, Stitzenberg KB
Use and costs of sentinel lymph node biopsy in non-ulcerated T1b melanoma: analysis of a population-based registry.
This study looked at the utility of sentinel lymph node biopsy (SLNB) for non-ulcerated T1b melanoma. The aim of the study was to estimate SLNB use, positivity, prevalence, and procedural costs in patients with non-ulcerated T1b melanoma using a population-based registry. Patients with clinically node-negative, non-ulcerated T1b melanoma were identified in the SEER database from 2010 to 2016. Among 7245 included patients, 53% underwent SLNB of which 156 (4.1%) had a positive SLNB. Higher odds of positivity were associated with younger age, >1 mitosis per mm2, female sex, and truncal tumor location. Estimated SLNB costs to identify one patient with Stage II disease was $71,700. Out-of-pocket expenses for a Medicare patient was estimated to be $652 for a wide local excision (WLE) and SLNB and $79 for WLE alone.
AHRQ-funded; HS000032.
Citation:
Herb JN, Ollila DW, Stitzenberg KB .
Use and costs of sentinel lymph node biopsy in non-ulcerated T1b melanoma: analysis of a population-based registry.
Ann Surg Oncol 2021 Jul;28(7):3470-78. doi: 10.1245/s10434-021-09998-6..
Keywords:
Cancer: Skin Cancer, Cancer, Surgery, Healthcare Costs, Skin Conditions
Shaheen MS, Silverberg JI
Association of inflammatory skin diseases with venous thromboembolism in US adults.
Patients with certain inflammatory skin diseases have multiple risk factors for venous thromboembolism (VTE). The objective of the study was to determine whether atopic dermatitis (AD), psoriasis, pemphigus, pemphigoid and/or hidradenitis was associated with VTE in US adults. Data were analyzed from the 2002-2012 Nationwide Inpatient Sample, a representative cohort of US hospitalizations.
AHRQ-funded; HS023011.
Citation:
Shaheen MS, Silverberg JI .
Association of inflammatory skin diseases with venous thromboembolism in US adults.
Arch Dermatol Res 2021 May;313(4):281-89. doi: 10.1007/s00403-020-02099-6..
Keywords:
Healthcare Cost and Utilization Project (HCUP), Skin Conditions, Blood Clots, Risk
Goldfarb N, Lowes MA, Butt M
Hidradenitis Suppurativa Area and Severity Index Revised (HASI-R): psychometric property assessment.
This study’s objective was to assess the reliability and validity of the Hidradenitis suppurative (HS) Area and Severity Index Revised (HASI-R) tool to assess HS severity. This tool incorporates signs of inflammation and body surface area involved while current tools to measure severity relies on lesion counts, which are time-consuming and unreliable. Measurement properties of HASI-R were evaluated. Twenty raters evaluated 15 HS patients in a hospital-based ambulatory dermatology clinic. Inter- and intra-rater reliability of the HASI-R and its components were assessed, as well as its construct and known-groups validity. The HASI-R was found to have moderate inter-rater reliability and the highest intra-rater reliability of all HS severity assessment tools. It also had good construct validity and demonstrated known-groups validity.
AHRQ-funded; HS024585.
Citation:
Goldfarb N, Lowes MA, Butt M .
Hidradenitis Suppurativa Area and Severity Index Revised (HASI-R): psychometric property assessment.
Br J Dermatol 2021 May;184(5):905-12. doi: 10.1111/bjd.19565..
Keywords:
Skin Conditions, Diagnostic Safety and Quality
Narla S, Silverberg JI
The inpatient burden and comorbidities of pyoderma gangrenosum in adults in the United States.
The objective of this study was to determine the prevalence, predictors, outcomes, and costs of hospitalization for pyoderma gangrenosum (PG) in United States adults. Data from the 2002-2012 National Inpatient Sample were analyzed. Findings showed that PG admissions were more likely at teaching and medium or large hospitals. The majority of inpatients with PG were classified with minor or moderate likelihood of dying, but moderate and major loss of function. PG was associated with numerous other health disorders. This study demonstrated a substantial and increasing inpatient burden of PG in the United States, with considerable disability and mortality risk, multiple comorbid health disorders, and costs.
AHRQ-funded; HS023011.
Citation:
Narla S, Silverberg JI .
The inpatient burden and comorbidities of pyoderma gangrenosum in adults in the United States.
Arch Dermatol Res 2021 May;313(4):245-53. doi: 10.1007/s00403-020-02098-7..
Keywords:
Healthcare Cost and Utilization Project (HCUP), Skin Conditions, Injuries and Wounds, Hospitalization, Healthcare Costs
Silverberg JI, Lei D, Yousaf M
What are the best endpoints for eczema area and severity index and scoring atopic dermatitis in clinical practice? A prospective observational study.
This prospective observational study’s objective was to determine the minimal important changes (MICs) of the Eczema Area and Severity Index (EASI) and Scoring Atopic Dermatitis (SCORAD) across all severities of atopic dermatitis (AD). Questionnaires and evaluation by a dermatologist (n =826) were used to determine the MIC of percentage and absolute improvement of EASI and SCORAD scores in adults and children. Absolute MICs for EASI, SCORAD, and O-SCORAD varied by baseline severity and EASI 50, SCORAD 35 and O-SCORAD 35 were meaningful percentage MICs regardless of baseline AD severity.
AHRQ-funded; HS023011.
Citation:
Silverberg JI, Lei D, Yousaf M .
What are the best endpoints for eczema area and severity index and scoring atopic dermatitis in clinical practice? A prospective observational study.
Br J Dermatol 2021 May;184(5):888-95. doi: 10.1111/bjd.19457..
Keywords:
Skin Conditions, Patient-Centered Outcomes Research, Evidence-Based Practice
Kirby JS, Hereford B, Thorlacius L
Validation of global item for assessing impact on quality of life of patients with Hidradenitis suppurativa.
Hidradenitis suppurativa (HS) is a chronic inflammatory disease. The HS core outcome set calls for a patient global assessment (PtGA). The objective of this study was to assess the validity, reliability and responsiveness of a candidate single-item PtGA for HS-specific health-related quality of life (HRQoL). The investigators concluded that the single-item PtGA exhibited reliability, validity and responsiveness in assessing HS-specific HRQoL in HS, making it a good provisional tool for HS clinical research.
AHRQ-funded; HS024585.
Citation:
Kirby JS, Hereford B, Thorlacius L .
Validation of global item for assessing impact on quality of life of patients with Hidradenitis suppurativa.
Br J Dermatol 2021 Apr;184(4):681-87. doi: 10.1111/bjd.19344..
Keywords:
Skin Conditions, Quality of Life, Chronic Conditions
Neubauer HC, Hall M, Lopez MA
Antibiotic regimens and associated outcomes in children hospitalized with staphylococcal scalded skin syndrome.
Controversy exists regarding the optimal antibiotic regimen for use in hospitalized children with staphylococcal scalded skin syndrome (SSSS). Various regimens may confer toxin suppression and/or additional coverage for methicillin-susceptible Staphylococcus aureus (MSSA) or methicillin-resistant S aureus (MRSA). The purpose of this study was to describe antibiotic regimens in hospitalized children with SSSS and examine the association between antistaphylococcal antibiotic regimens and patient outcomes.
AHRQ-funded; HS026006.
Citation:
Neubauer HC, Hall M, Lopez MA .
Antibiotic regimens and associated outcomes in children hospitalized with staphylococcal scalded skin syndrome.
J Hosp Med 2021 Mar;16(3):149-55. doi: 10.12788/jhm.3529..
Keywords:
Children/Adolescents, Antibiotics, Medication, Methicillin-Resistant Staphylococcus aureus (MRSA), Skin Conditions, Infectious Diseases
Silverberg JI, Lei D, Yousaf M
Measurement properties of the product of investigator's global assessment and body surface area in children and adults with atopic dermatitis.
This study’s goal was to determine the measurement properties of the product of validated Investigator’s Global Assessment for AD and body surface area (vIGA*BSA) for atopic dermatitis (AD) severity. The authors performed a prospective practice-based study using questionnaires and evaluation by a dermatologist (n = 653). The vIGA*BSA can also be divided into six categories (vIGA*cBSA: 0%/0.1, <10%/10, <30%/30, <50%/50, <70%/70 and <90%/90-100%)). The assessment was compared with other rating scales such as SCORAD, Patient-Oriented Eczema Measure, Dermatology Life Quality Index, ItchyOOL, PROMISE Sleep Disturbance, and sleep-related impairment. Scores showed good convergent and discriminant validity, reliability, responsiveness and interpretability in adults and children with AD.
AHRQ-funded; HS023011.
Citation:
Silverberg JI, Lei D, Yousaf M .
Measurement properties of the product of investigator's global assessment and body surface area in children and adults with atopic dermatitis.
J Eur Acad Dermatol Venereol 2021 Jan;35(1):180-87. doi: 10.1111/jdv.16846..
Keywords:
Children/Adolescents, Skin Conditions, Patient-Centered Outcomes Research, Evidence-Based Practice
Silverberg JI, Lei D, Yousaf M
Measurement properties of the Rajka-Langeland severity score in children and adults with atopic dermatitis.
This study looked at the measurement properties of the Rajka-Langeland severity score for atopic dermatitis (AD) in children and adults and compared it with other clinician-reported outcomes. The study used questionnaires and evaluation by a dermatologist (n = 427). Rajka-Langeland had good concurrent validity with the Eczema Area and Severity Index and body surface area; good convergent validity with the numeric rating scale average-itch and worst-itch, Patient-Oriented Eczema Measure, Dermatology Life Quality Index, Patient Reported Outcomes Measurement Information System Itch Questionnaire in adults and/or children; fair discriminant validity for patient- and physician reported global AD severity; good responsive to change of severity of AD and itch; and good reliability, internal consistency; with no floor or ceiling effects.
AHRQ-funded; HS023011.
Citation:
Silverberg JI, Lei D, Yousaf M .
Measurement properties of the Rajka-Langeland severity score in children and adults with atopic dermatitis.
Br J Dermatol 2021 Jan;184(1):87-95. doi: 10.1111/bjd.19159..
Keywords:
Children/Adolescents, Skin Conditions, Patient-Centered Outcomes Research, Evidence-Based Practice
Stone CA, Trubiano JA, Phillips EJ
Testing strategies and predictors for evaluating immediate and delayed reactions to cephalosporins.
Although 1% to 2% of the general population carries a cephalosporin allergy label (CAL), there is a lack of validated testing strategies and predictors of true allergy. The objective of this study was to identify cross-reactivity patterns and predictors of skin test positive (STP) in geographically disparate patients with a CAL. The investigators found that cephalosporin cross-reactivity was based on shared R1 groupings. Increasing time since the original reaction and the presence of a PAL with unknown cephalosporin tolerance predicted a lower likelihood of cephalosporin STP.
AHRQ-funded; HS026395.
Citation:
Stone CA, Trubiano JA, Phillips EJ .
Testing strategies and predictors for evaluating immediate and delayed reactions to cephalosporins.
J Allergy Clin Immunol Pract 2021 Jan;9(1):435-44e13. doi: 10.1016/j.jaip.2020.07.056..
Keywords:
Antibiotics, Medication, Adverse Drug Events (ADE), Adverse Events, Skin Conditions, Diagnostic Safety and Quality
Hong MR, Lei D, Yousaf M
A real-world study of the longitudinal course of adult atopic dermatitis severity in clinical practice.
This study examined the longitudinal course of adult atopic dermatitis (AD) severity in clinical practice. Dermatology patients were assessed at approximately 6,12, 18, and 24 months by the scoring systems Eczema Area and Severity Index (EASI) and objective-Scoring Atopic Dermatitis (objective-SCORAD). At any visit, 36.2% of cases were scored as moderate, and 18.2% were severe. Among those patients, 25% and 18.6% continued to have moderate or severe scores at 1 or more follow-up visits for EASI, and 22.6% and 24.5% moderate or severe objective-SCORAD scores respectively. Many patients had fluctuating severity scores over time and a minority had persistently moderate or severe lesions over time, and most of those patients were unable to achieve persistent lesional clearance.
AHRQ-funded; HS023011.
Citation:
Hong MR, Lei D, Yousaf M .
A real-world study of the longitudinal course of adult atopic dermatitis severity in clinical practice.
Ann Allergy Asthma Immunol 2020 Dec;125(6):686-92.e3. doi: 10.1016/j.anai.2020.07.005.
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Keywords:
Skin Conditions, Patient-Centered Outcomes Research, Evidence-Based Practice
Gelfand JM, Armstrong AW, Bell S
National Psoriasis Foundation COVID-19 Task Force guidance for management of psoriatic disease during the pandemic: Vversion 1.
This article describes the process that was used to create the first version of a guidance document for management of psoriatic disease during the COVID-19 pandemic developed by the National Psoriasis Foundation. A task force of 18 physician voting members with expertise in dermatology, rheumatology, epidemiology, infectious diseases, and critical care was created with supplementation by nonvoting members. A Delphi process was created, out of which 22 guidance statements were approved. All guidance statements were recommended, with 9 of them high consensus, and the remaining 13 were moderate consensus. Topics covered included how COVID-19 can impact patients, how medical care can be optimized during the pandemic, and what patients can do to lower their risk of getting infected with COVID-19. This guidance will be updated by the TF as new data emerges.
AHRQ-funded; HS026372.
Citation:
Gelfand JM, Armstrong AW, Bell S .
National Psoriasis Foundation COVID-19 Task Force guidance for management of psoriatic disease during the pandemic: Vversion 1.
J Am Acad Dermatol 2020 Dec;83(6):1704-16. doi: 10.1016/j.jaad.2020.09.001..
Keywords:
Skin Conditions, Chronic Conditions, Care Management, Evidence-Based Practice, Guidelines, COVID-19
Silverberg JI, Lei D, Yousaf M
Association of itch triggers with atopic dermatitis severity and course in adults.
Atopic dermatitis (AD) is associated with heterogeneous triggers of itch, which may affect AD course and severity. The objective of this study was to characterize the triggers of itch in adult AD. The investigators concluded that itch triggers were common and affected the course of AD. They noted that itch triggers are an important end point to assess in patients with AD.
AHRQ-funded; HS023011.
Citation:
Silverberg JI, Lei D, Yousaf M .
Association of itch triggers with atopic dermatitis severity and course in adults.
Ann Allergy Asthma Immunol 2020 Nov;125(5):552-59.e2. doi: 10.1016/j.anai.2020.06.014..
Keywords:
Skin Conditions, Diagnostic Safety and Quality
