National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
26 to 50 of 71 Research Studies DisplayedFaye AS, Polubriaginof F, Green PHR
Low rates of screening for celiac disease among family members.
This study determined how many family members of patients diagnosed with celiac disease were screened. Even among those patients with a family history, nearly 30% of symptomatic first-degree relatives were not tested. These tests are recommended in guidelines for all relatives with a documented family history.
AHRQ-funded; HS021816.
Citation: Faye AS, Polubriaginof F, Green PHR .
Low rates of screening for celiac disease among family members.
Clin Gastroenterol Hepatol 2019 Feb;17(3):463-68. doi: 10.1016/j.cgh.2018.06.016..
Keywords: Diagnostic Safety and Quality, Digestive Disease and Health, Family Health and History, Screening
Simon NJ, Richardson J, Ahmad A
Health utilities and parental quality of life effects for three rare conditions tested in newborns.
The purposes of this study were to estimate health utilities for three rare, heritable conditions currently recommended for newborn screening - Krabbe disease, phenylketonuria, and Pompe disease - and to estimate the spillover effects experienced by the parents of infants diagnosed with these disorders. A survey elicited health utilities for the three conditions at varying stages and onset of symptoms. Respondents valued disease specific health states in three question frames: adult, child, and parent spillover state. Results reported that more severe conditions and infant health states received lower estimated utility, and estimates of greater disutility among parents.
AHRQ-funded; HS020644.
Citation: Simon NJ, Richardson J, Ahmad A .
Health utilities and parental quality of life effects for three rare conditions tested in newborns.
J Patient Rep Outcomes 2019 Jan 22;3(1):4. doi: 10.1186/s41687-019-0093-6..
Keywords: Caregiving, Family Health and History, Newborns/Infants, Quality of Life, Screening
Kim DH, Bassett SM, So S
Family stress and youth mental health problems: self-efficacy and future orientation mediation.
This study assessed whether future orientation and self-esteem affected the relationship between family stress and mental health problems among African American youth in predominantly low-income neighborhoods. Youths (mainly female, average age 15.83 years old) were sampled for family stress, self-esteem, future orientation, mental health and other covariates such as gender and sexual orientation. A correlation was found between future orientation and self-esteem levels and family stress and mental health problems.
AHRQ-funded; HS000078.
Citation: Kim DH, Bassett SM, So S .
Family stress and youth mental health problems: self-efficacy and future orientation mediation.
Am J Orthopsychiatry 2019;89(2):125-33. doi: 10.1037/ort0000371..
Keywords: Children/Adolescents, Family Health and History, Low-Income, Behavioral Health, Racial and Ethnic Minorities, Stress, Vulnerable Populations
Fiechtner L, Fonte ML, Castro I
Determinants of binge eating symptoms in children with overweight/obesity.
In this study, the investigators examined the prevalence and multilevel determinants of three binge eating symptoms: (1) sneaking, hiding, or hoarding food; (2) eating in the absence of hunger, and (3) inhibition or embarrassment when eating in front of others among 817 children aged 5-12 years old with overweight/obesity receiving primary care in eastern Massachusetts. They examined the associations of child and parent/household characteristics with the prevalence ratios (PRs) of these three binge eating symptoms.
AHRQ-funded; HS024332; HS022986.
Citation: Fiechtner L, Fonte ML, Castro I .
Determinants of binge eating symptoms in children with overweight/obesity.
Child Obes 2018 Nov/Dec;14(8):510-17. doi: 10.1089/chi.2017.0311..
Keywords: Children/Adolescents, Obesity: Weight Management, Obesity, Nutrition, Family Health and History, Patient-Centered Healthcare
Parrish KL, Hogan PG, Clemons AA
Spatial relationships among public places frequented by families plagued by methicillin-resistant Staphylococcus aureus.
In this study, the investigators mapped public places (including personal service establishments, fitness centers, pools, schools, and daycares) visited by members of households affected by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infection, in order to understand factors associated with CA-MRSA acquisition and infection.
AHRQ-funded; HS024269; HS021736.
Citation: Parrish KL, Hogan PG, Clemons AA .
Spatial relationships among public places frequented by families plagued by methicillin-resistant Staphylococcus aureus.
BMC Res Notes 2018 Oct 1;11(1):692. doi: 10.1186/s13104-018-3797-4..
Keywords: Community-Acquired Infections, Family Health and History, Methicillin-Resistant Staphylococcus aureus (MRSA)
Crossman MK, Parish SL, Hauser-Cram P
The influence of early intervention, informal support and the family environment on trajectories of competence for fathers raising children with developmental disabilities.
The aims of this study are: (1) To determine the trajectory of parental competence for fathers of children with developmental disabilities from age 3 to age 15; (2) Controlling for child and family characteristics, determine the main effects of the family environment, informal support, and early intervention (EI) services on paternal competence when their child with a developmental disability was age 3; and (3) To determine whether there were lasting effects of the family environment, informal support, and the EI service system on differences in paternal competence over time.
AHRQ-funded; HS000063.
Citation: Crossman MK, Parish SL, Hauser-Cram P .
The influence of early intervention, informal support and the family environment on trajectories of competence for fathers raising children with developmental disabilities.
Res Dev Disabil 2018 Oct;81:122-33. doi: 10.1016/j.ridd.2018.04.025..
Keywords: Caregiving, Children/Adolescents, Disabilities, Family Health and History
Muenks CE, Sewell WC, Hogan PG
Methicillin-resistant staphylococcus aureus: the effects are more than skin deep.
The purpose of the study was to assess the psychosocial effects of a methicillin-resistant Staphylococcus aureus (MRSA) diagnosis on the households of children with MRSA skin and soft tissue infection (SSTI). The study found that primary caregivers of children with MRSA SSTI reported changing their health behaviors, altering their interactions with people outside of their home, and feeling isolated by others in response to their child's MRSA diagnosis.
AHRQ-funded; HS021736.
Citation: Muenks CE, Sewell WC, Hogan PG .
Methicillin-resistant staphylococcus aureus: the effects are more than skin deep.
J Pediatr 2018 Aug;199:158-65. doi: 10.1016/j.jpeds.2018.04.002..
Keywords: Caregiving, Children/Adolescents, Family Health and History, Methicillin-Resistant Staphylococcus aureus (MRSA), Social Stigma
Polubriaginof FCG, Vanguri R, Quinnies K
Disease heritability inferred from familial relationships reported in medical records.
Electronic health records (EHRs) passively capture a wide range of clinically relevant data and provide a resource for studying the heritability of traits that are not typically accessible. This study used EHR data to compute heritability estimates for 500 disease phenotypes. These analyses provided a validation of the use of EHRs for genetics and disease research.
AHRQ-funded; HS021816; HS022961.
Citation: Polubriaginof FCG, Vanguri R, Quinnies K .
Disease heritability inferred from familial relationships reported in medical records.
Cell 2018 Jun 14;173(7):1692-704.e11. doi: 10.1016/j.cell.2018.04.032..
Keywords: Data, Family Health and History, Genetics, Health Information Technology (HIT), Electronic Health Records (EHRs)
Churchill SS, Kieckhefer GM
One year follow-up of outcomes from the randomized clinical trial of the building on family strengths program.
This study tested the 12-month efficacy of an inclusive non-diagnosis-specific, parent education program with seven in-person sessions. The outcome measures were self-efficacy, parent and child shared management of chronic condition, coping skills, parental depressive symptoms and quality of life. All of the outcomes improved within the intervention group over 12 months.
AHRQ-funded; HS013384.
Citation: Churchill SS, Kieckhefer GM .
One year follow-up of outcomes from the randomized clinical trial of the building on family strengths program.
Matern Child Health J 2018 Jun;22(6):913-21. doi: 10.1007/s10995-018-2467-4.
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Keywords: Children/Adolescents, Chronic Conditions, Education: Patient and Caregiver, Family Health and History, Patient and Family Engagement
Roberts MC, Dotson WD, DeVore CS
AHRQ Author: Ganiats TG
Delivery of cascade screening for hereditary conditions: a scoping review of the literature.
The authors conducted a scoping review to obtain a broad overview of cascade screening interventions, facilitators and barriers to their use, relevant policy considerations, and future research needs. They sought standardized best practices for optimizing cascade screening across various geographic and policy contexts, but found none. Studies in which trained providers contacted relatives directly, rather than through probands (index patients), showed greater cascade screening uptake; however, policies in some states might limit this approach.
AHRQ-authored.
Citation: Roberts MC, Dotson WD, DeVore CS .
Delivery of cascade screening for hereditary conditions: a scoping review of the literature.
Health Aff 2018 May;37(5):801-08. doi: 10.1377/hlthaff.2017.1630.
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Keywords: Family Health and History, Genetics, Policy, Screening
Fiechtner L, Perkins M, Biggs V
Rationale and design of the Clinic and Community Approaches to Healthy Weight Randomized Trial.
Recent studies have demonstrated the effectiveness of family-centered, pediatric weight management programs in reducing childhood obesity. Yet, programs to optimize the care of low-income children with obesity are needed. The investigators sought to examine the comparative effectiveness of two, potentially scalable pediatric weight management programs delivered to low-income children in a clinical or community setting.
AHRQ-funded; HS024332; HS022986.
Citation: Fiechtner L, Perkins M, Biggs V .
Rationale and design of the Clinic and Community Approaches to Healthy Weight Randomized Trial.
Contemp Clin Trials 2018 Apr;67:16-22. doi: 10.1016/j.cct.2018.01.002..
Keywords: Children/Adolescents, Obesity: Weight Management, Obesity, Low-Income, Vulnerable Populations, Nutrition, Patient-Centered Healthcare, Family Health and History, Evidence-Based Practice, Comparative Effectiveness
Crossman MK, Warfield ME, Kotelchuck M
Associations between early intervention home visits, family relationships and competence for mothers of children with developmental disabilities.
The researchers examined the association between intensity of home visits in early intervention (EI), perceived helpfulness of home visits in EI, and positive family relationships as predictors of maternal competence at age 3, as well as moderating effects of predictors, controlling for child characteristics, family demographics, and negative life events. They found that the intensity of home visits was not significantly associated with maternal competence at age 3.
AHRQ-funded; HS000063.
Citation: Crossman MK, Warfield ME, Kotelchuck M .
Associations between early intervention home visits, family relationships and competence for mothers of children with developmental disabilities.
Matern Child Health J 2018 Apr;22(4):599-607. doi: 10.1007/s10995-018-2429-x.
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Keywords: Children/Adolescents, Disabilities, Family Health and History, Patient and Family Engagement
Shah AN, Beck AF, Sucharew HJ
Parental adverse childhood experiences and resilience on coping after discharge.
Researchers sought to quantify adverse childhood experiences (ACEs) and resilience scores for parents of hospitalized children and evaluate their associations to parental coping after discharge. They concluded that more parental adversity and less resilience are associated with parental coping difficulties after discharge, representing potentially important levers for transition-focused interventions.
AHRQ-funded; HS024735.
Citation: Shah AN, Beck AF, Sucharew HJ .
Parental adverse childhood experiences and resilience on coping after discharge.
Pediatrics 2018 Apr;141(4). doi: 10.1542/peds.2017-2127.
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Keywords: Caregiving, Children/Adolescents, Domestic Violence, Family Health and History, Hospitalization
Harper KJ, Osborn CY, Mayberry LS
Patient-perceived family stigma of type 2 diabetes and its consequences.
The objective of this study was to assess the frequency of type two diabetes (T2D) family stigma and its association with helpful and harmful diabetes-specific family behaviors and psychological and behavioral consequences of stigma. Perceptions/experiences of T2D-related family stigma were common in the study’s sample and associated with consequences of stigma including concealment and resentment of self-care, which may affect clinical outcomes.
AHRQ-funded; HS022990.
Citation: Harper KJ, Osborn CY, Mayberry LS .
Patient-perceived family stigma of type 2 diabetes and its consequences.
Fam Syst Health 2018 Mar;36(1):113-17. doi: 10.1037/fsh0000316..
Keywords: Diabetes, Family Health and History, Social Stigma
Ragavan MI, Fikre T, Millner U
The impact of domestic violence exposure on South Asian children in the United States: perspectives of domestic violence agency staff.
The goal of this study was to examine the needs of South Asian children subjected to domestic violence, from the perspective of staff in domestic violence agencies across the U.S. in order to determine if the children required culture-specific resources. Thirty interviews were conducted; participants described factors important to understanding the impact of domestic violence on South Asian children and discussed the development of culturally tailored resources. The findings suggests that framing South Asian children's experiences within the context of interweaving South Asian and American cultural values, with attention focused on how potential culture clashes may impact the way children that process trauma, is important. The authors recommend that further work triangulate these themes between children, parents, and extended family and in collaboration with domestic violence agencies.
AHRQ-funded; HS022242.
Citation: Ragavan MI, Fikre T, Millner U .
The impact of domestic violence exposure on South Asian children in the United States: perspectives of domestic violence agency staff.
Child Abuse Negl 2018 Feb;76:250-60. doi: 10.1016/j.chiabu.2017.11.006..
Keywords: Access to Care, Children/Adolescents, Cultural Competence, Domestic Violence, Family Health and History, Racial and Ethnic Minorities, Vulnerable Populations
Naber SK, Kuntz KM, Henrikson NB
AHRQ Author: Ganiats TG
Cost effectiveness of age-specific screening intervals for people with family histories of colorectal cancer.
Despite relative risk of colorectal cancer (CRC) decreasing with age among individuals with a family history of CRC, no screening recommendations specify less frequent screening. Researchers found that for individuals with a family history of CRC, it is cost effective to gradually increase the screening interval if several subsequent screening colonoscopies have negative results and no new cases of CRC are found in family members.
AHRQ-authored.
Citation: Naber SK, Kuntz KM, Henrikson NB .
Cost effectiveness of age-specific screening intervals for people with family histories of colorectal cancer.
Gastroenterology 2018 Jan;154(1):105-16.e20. doi: 10.1053/j.gastro.2017.09.021.
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Keywords: Cancer: Colorectal Cancer, Healthcare Costs, Family Health and History, Risk, Screening
Barbour WL, Rodgers JB, Wang HE
Human immunodeficiency virus risk factors and beliefs reported by families presenting to a pediatric emergency department.
This study compared HIV risk behaviors reported by adolescents to parents' perception of adolescent risky behavior engagement and examined participants' knowledge of HIV transmission and testing preferences. The study concluded that: Parents are mostly unaware of adolescents' broad risk behaviors; Participants' knowledge of HIV transmission is limited; Adolescents and parents shared strong agreement regarding HIV testing preferences.
AHRQ-funded; HS013852.
Citation: Barbour WL, Rodgers JB, Wang HE .
Human immunodeficiency virus risk factors and beliefs reported by families presenting to a pediatric emergency department.
Pediatr Emerg Care 2018 Jan;34(1):1-5. doi: 10.1097/pec.0000000000000536..
Keywords: Children/Adolescents, Emergency Department, Family Health and History, Human Immunodeficiency Virus (HIV), Risk
Berge JM, Truesdale KP, Sherwood NE
Beyond the dinner table: who's having breakfast, lunch and dinner family meals and which meals are associated with better diet quality and BMI in pre-school children?.
This study examined the frequency of eating breakfast, lunch or dinner family meals and associations with pre-school children's overall diet quality and BMI percentile. The authors concluded that breakfast family meal frequency and total weekly family meal frequency were associated with healthier diet quality in non-Hispanic pre-school children but not in Hispanic children. Longitudinal research is needed to clarify the association between family meal type and child diet quality and BMI percentile.
AHRQ-funded; HS022990.
Citation: Berge JM, Truesdale KP, Sherwood NE .
Beyond the dinner table: who's having breakfast, lunch and dinner family meals and which meals are associated with better diet quality and BMI in pre-school children?.
Public Health Nutr 2017 Dec;20(18):3275-84. doi: 10.1017/s1368980017002348..
Keywords: Children/Adolescents, Family Health and History, Nutrition, Obesity: Weight Management, Racial and Ethnic Minorities
Childers CP, Childers KK, Maggard-Gibbons M
National estimates of genetic testing in women with a history of breast or ovarian cancer.
In the United States, 3.8 million women have a history of breast (BC) or ovarian cancer (OC). Up to 15 percent of cases are attributable to heritable mutations, which, if identified, provide critical knowledge for treatment and preventive care. This study found that fewer than one in five individuals with a history of BC or OC meeting select National Cancer Comprehensive Network criteria have undergone genetic testing.
AHRQ-funded; HS025079.
Citation: Childers CP, Childers KK, Maggard-Gibbons M .
National estimates of genetic testing in women with a history of breast or ovarian cancer.
J Clin Oncol 2017 Dec 1;35(34):3800-06. doi: 10.1200/jco.2017.73.6314.
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Keywords: Cancer, Cancer: Breast Cancer, Cancer: Ovarian Cancer, Family Health and History, Genetics, Quality of Care, Screening, Women
Mabry-Hernandez I, Gottfredson R
AHRQ Author: Mabry-Hernandez I
Screening for lipid disorders in children and adolescents.
This case study concerns a healthy 12-year-old boy presenting for a school physical and well visit. His family history reveals that his maternal grandfather had a heart attack and that his father has started taking a medication for elevated cholesterol levels. His mother is concerned about his genetic risk of a cholesterol disorder and asks if he should be screened. The article poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: Mabry-Hernandez I, Gottfredson R .
Screening for lipid disorders in children and adolescents.
Am Fam Physician 2017 Oct 15;96(8):529-30.
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Keywords: Children/Adolescents, Family Health and History, Screening, U.S. Preventive Services Task Force (USPSTF)
Wong MS, Jones-Smith JC, Colantuoni E
The longitudinal association between early childhood obesity and fathers' involvement in caregiving and decision-making.
This study assessed the longitudinal association between changes in obesity among children aged 2 to 4 years and changes in fathers' involvement with raising children. Children whose fathers increased their frequency of taking children outside and involvement with physical childcare experienced a decrease in their odds of obesity from age 2 to age 4.
AHRQ-funded; HS000029.
Citation: Wong MS, Jones-Smith JC, Colantuoni E .
The longitudinal association between early childhood obesity and fathers' involvement in caregiving and decision-making.
Obesity 2017 Oct;25(10):1754-61. doi: 10.1002/oby.21902.
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Keywords: Caregiving, Children/Adolescents, Family Health and History, Obesity, Patient-Centered Healthcare
Hong MK, Feustel C, Agnihotri M
Supporting families in reviewing and communicating about radiology imaging studies.
Diagnostic radiology reports are increasingly being made available to patients and their family members. However, these reports are not typically comprehensible to lay recipients, impeding effective communication about report findings. In this paper, the investigators present three studies informing the design of a prototype to foster patient-clinician communication about radiology report content.
AHRQ-funded; HS021393.
Citation: Hong MK, Feustel C, Agnihotri M .
Supporting families in reviewing and communicating about radiology imaging studies.
Proc SIGCHI Conf Hum Factor Comput Syst 2017 May 2;2017:5245-56. doi: 10.1145/3025453.3025754..
Keywords: Communication, Family Health and History, Imaging, Clinician-Patient Communication
Jolles MP, Flick JAJ, Wells R
Caregiver involvement in behavioural health services in the context of child welfare service referrals: a qualitative study.
This study presents findings from a qualitative study of caregivers involved with child welfare agencies who were referred to behavioral health services. Findings suggest that when deciding to engage in services, caregivers weigh not only their individual and family behavioral health needs but also potential agency intervention, including loss of child custody.
AHRQ-funded; HS000032.
Citation: Jolles MP, Flick JAJ, Wells R .
Caregiver involvement in behavioural health services in the context of child welfare service referrals: a qualitative study.
Child Fam Soc Work 2017 May;22(2):648-59. doi: 10.1111/cfs.12279.
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Keywords: Children/Adolescents, Caregiving, Behavioral Health, Family Health and History
Aschbrenner KA, Mueser KT, Naslund JA
Facilitating partner support for lifestyle change among adults with serious mental illness: a feasibility pilot study.
The purpose of this pilot study was to explore the feasibility of an intervention designed to facilitate partner support for lifestyle change among overweight and obese adults with serious mental illness. After 12 weeks, approximately two-thirds of participants were below their baseline weight at follow-up, including 27 percent who achieved clinically significant weight loss.
AHRQ-funded; HS021695.
Citation: Aschbrenner KA, Mueser KT, Naslund JA .
Facilitating partner support for lifestyle change among adults with serious mental illness: a feasibility pilot study.
Community Ment Health J 2017 May;53(4):394-404. doi: 10.1007/s10597-017-0100-4.
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Keywords: Family Health and History, Lifestyle Changes, Behavioral Health, Obesity, Obesity: Weight Management
Heerman WJ, Taylor JL, Wallston KA
Parenting self-efficacy, parent depression, and healthy childhood behaviors in a low-income minority population: a cross-sectional analysis.
The study’s objective was to measure the associations between parenting self-efficacy, parent depressive symptoms, and preschool child behaviors that support healthy growth. It found that in this minority population, higher parenting self-efficacy was associated with longer child sleep and fewer meals in front of the TV, but parent depressive symptoms mitigated that protective effect for child sleep duration.
AHRQ-funded; HS022990.
Citation: Heerman WJ, Taylor JL, Wallston KA .
Parenting self-efficacy, parent depression, and healthy childhood behaviors in a low-income minority population: a cross-sectional analysis.
Matern Child Health J 2017 May;21(5):1156-65. doi: 10.1007/s10995-016-2214-7.
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Keywords: Children/Adolescents, Family Health and History, Depression, Racial and Ethnic Minorities, Low-Income