National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
10676 to 10700 of 12139 Research Studies DisplayedMasho SW, Cha S, Morris MR
Prepregnancy obesity and breastfeeding noninitiation in the United States: an examination of racial and ethnic differences.
This study used a large, nationally representative sample to assess racial/ethnic differences in breastfeeding noninitiation among U.S. women of different body mass index (BMI) classifications. It found that prepregnancy BMI is a significant predictor for breastfeeding noninitiation for non-Hispanic white and non-Hispanic black women.
AHRQ-funded; HS021504.
Citation: Masho SW, Cha S, Morris MR .
Prepregnancy obesity and breastfeeding noninitiation in the United States: an examination of racial and ethnic differences.
Breastfeed Med 2015 Jun;10(5):253-62. doi: 10.1089/bfm.2015.0006..
Keywords: Breast Feeding, Obesity, Racial and Ethnic Minorities, Racial and Ethnic Minorities
Saeed MJ, Dubberke ER, Fraser VJ
Procedure-specific surgical site infection incidence varies widely within certain National Healthcare Safety Network surgery groups.
The objective of this study was to determine surgical site infection (SSI) incidence for clinically defined subgroups within 5 heterogeneous National Healthcare Safety Network surgery categories (amputation; bile duct, liver or pancreas; breast; colon; and hernia) in community hospitals in California, Florida, and New York. The 90-day SSI rates varied significantly within each of the 5 subgroups.
AHRQ-funded; HS019455.
Citation: Saeed MJ, Dubberke ER, Fraser VJ .
Procedure-specific surgical site infection incidence varies widely within certain National Healthcare Safety Network surgery groups.
Am J Infect Control 2015 Jun;43(6):617-23. doi: 10.1016/j.ajic.2015.02.012..
Keywords: Healthcare Cost and Utilization Project (HCUP), Surgery, Patient Safety, Adverse Events
Merlin JS, Westfall AO, Chamot E
Quantitative evaluation of an instrument to identify chronic pain in HIV-infected individuals.
The researchers assessed the construct validity of the two-question Brief Chronic Pain Questionnaire (BCPQ) in HIV-infected patients by assessing the association between BCPQ responses and known correlates of chronic pain. Their study provides preliminary evidence for the BCPQ as a brief questionnaire to identify the presence of chronic pain in HIV care settings.
AHRQ-funded; HS021694.
Citation: Merlin JS, Westfall AO, Chamot E .
Quantitative evaluation of an instrument to identify chronic pain in HIV-infected individuals.
AIDS Res Hum Retroviruses 2015 Jun;31(6):623-7. doi: 10.1089/aid.2014.0362..
Keywords: Chronic Conditions, Human Immunodeficiency Virus (HIV), Pain
Giardina TD, Callen J, Georgiou A
Releasing test results directly to patients: a multisite survey of physician perspectives.
The researchers conducted a cross-sectional survey to explore physician perspectives about direct test result notification to patients in two countries, the U.S. and Australia. They found that physicians have substantial concerns about direct notification of test results. Most concerns are about abnormal test results and more specifically about sensitive tests although physicians are generally in favor of direct notification of normal test results to patients.
AHRQ-funded; HS022087; HS023602.
Citation: Giardina TD, Callen J, Georgiou A .
Releasing test results directly to patients: a multisite survey of physician perspectives.
Patient Educ Couns 2015 Jun;98(6):788-96. doi: 10.1016/j.pec.2015.02.011..
Keywords: Electronic Health Records (EHRs), Health Information Technology (HIT)
Pruitt SL, Lee SJ, Tiro JA
Residential racial segregation and mortality among black, white, and Hispanic urban breast cancer patients in Texas, 1995 to 2009.
The authors investigated whether residential segregation was associated with mortality among urban women with breast cancer. They found that greater black segregation and Hispanic segregation were adversely associated with cause-specific mortality and all-cause mortality.
AHRQ-funded; HS022418.
Citation: Pruitt SL, Lee SJ, Tiro JA .
Residential racial segregation and mortality among black, white, and Hispanic urban breast cancer patients in Texas, 1995 to 2009.
Cancer 2015 Jun 1;121(11):1845-55. doi: 10.1002/cncr.29282..
Keywords: Cancer: Breast Cancer, Mortality, Patient-Centered Outcomes Research, Racial and Ethnic Minorities, Urban Health
Kane-Gill SL, Sileanu FE, Murugan R
Risk factors for acute kidney injury in older adults with critical illness: a retrospective cohort study.
The authors sought to delineate the determinants of risk for acute kidney injury (AKI) in older compared with younger adults. They found that among the risk factors for AKI in the oldest age category were drugs (vancomycin, aminoglycosides, and nonsteroidal anti-inflammatories), history of hypertension, and sepsis. Fewer variables remained predictive of AKI as age increased and the model for older patients was less predictive.
AHRQ-funded; HS018721.
Citation: Kane-Gill SL, Sileanu FE, Murugan R .
Risk factors for acute kidney injury in older adults with critical illness: a retrospective cohort study.
Am J Kidney Dis 2015 Jun;65(6):860-9. doi: 10.1053/j.ajkd.2014.10.018.
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Keywords: Elderly, Kidney Disease and Health, Medication, Risk, Sepsis
Tsai HT, Keating NL, Van Den Eeden SK
Risk of diabetes among patients receiving primary androgen deprivation therapy for clinically localized prostate cancer.
The researchers sought to determine if primary androgen deprivation therapy increases the risk of diabetes and to determine the susceptibility factors. They found that primary androgen deprivation therapy may increase diabetes risk by 60% and recommended using caution when managing localized prostate cancer. They further recommended routine screening and lifestyle interventions to reduce the risk of diabetes in men receiving androgen deprivation therapy.
AHRQ-funded; HS022915.
Citation: Tsai HT, Keating NL, Van Den Eeden SK .
Risk of diabetes among patients receiving primary androgen deprivation therapy for clinically localized prostate cancer.
J Urol 2015 Jun;193(6):1956-62. doi: 10.1016/j.juro.2014.12.027.
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Keywords: Adverse Drug Events (ADE), Diabetes, Medication, Cancer: Prostate Cancer, Risk
Yun H, Xie F, Delzell E
Risk of hospitalised infection in rheumatoid arthritis patients receiving biologics following a previous infection while on treatment with anti-TNF therapy.
The researchers compare the subsequent risk of hospitalized infections associated with specific biologic agents among RA patients previously hospitalized for infection while receiving anti-tumor necrosis factor (anti-TNF) therapy. They found that among rheumatoid arthritis patients who experienced a hospitalized infection while on anti-TNF therapy, abatacept and etanercept were associated with the lowest risk of a subsequent infection compared to other biologic therapies.
AHRQ-funded; HS021694; HS023009; HS018517.
Citation: Yun H, Xie F, Delzell E .
Risk of hospitalised infection in rheumatoid arthritis patients receiving biologics following a previous infection while on treatment with anti-TNF therapy.
Ann Rheum Dis 2015 Jun;74(6):1065-71. doi: 10.1136/annrheumdis-2013-204011..
Keywords: Arthritis, Healthcare-Associated Infections (HAIs), Healthcare-Associated Infections (HAIs), Patient-Centered Outcomes Research, Patient Safety
Curtis JR, Xie F, Yun H
Risk of hospitalized infection among rheumatoid arthritis patients concurrently treated with a biologic agent and denosumab.
The researchers evaluated rates of hospitalized infection among patients treated with biologic agents for RA who subsequently initiated denosumab in order to assess whether rates of infection were increased with concurrent biologic agent use for RA. They found that the rate of hospitalized infection among RA patients receiving denosumab concurrently with biologic agents for RA was not increased compared to those receiving zoledronate.
AHRQ-funded; HS018517
Citation: Curtis JR, Xie F, Yun H .
Risk of hospitalized infection among rheumatoid arthritis patients concurrently treated with a biologic agent and denosumab.
Arthritis Rheumatol. 2015 Jun;67(6):1456-64. doi: 10.1002/art.39075..
Keywords: Arthritis, Healthcare-Associated Infections (HAIs), Risk, Patient Safety, Comparative Effectiveness
Vemana G, Vetter J, Chen L
Sources of variation in follow-up expenditure after radical cystectomy.
Follow-up care after radical cystectomy is poorly defined, with extensive variation in practice patterns. The researchers sought to determine sources of these variations in care as well as examine the economic effect of standardization of care on guideline-recommended care. The most variation in expenditure on follow-up care was at the patient level, largely based on node positivity, chemotherapy status, and final cancer stage.
AHRQ-funded; HS019455.
Citation: Vemana G, Vetter J, Chen L .
Sources of variation in follow-up expenditure after radical cystectomy.
Urol Oncol 2015 Jun;33(6):267.e31-7. doi: 10.1016/j.urolonc.2015.03.009..
Keywords: Cancer, Surgery, Healthcare Costs, Elderly
Seitz AE, Adjemian J, Steiner CA
AHRQ Author: Steiner CA
Spatial epidemiology of blastomycosis hospitalizations: detecting clusters and identifying environmental risk factors.
The researchers used a single, multi-state dataset with standard methodology throughout the endemic area to provide new insights into the epidemiology of blastomycosis. They found that the odds of a county being part of a high-risk cluster was associated with increasing percentage of population over age 65, decreasing maximum temperature, increasing mercury, and decreasing copper soil content.
AHRQ-authored.
Citation: Seitz AE, Adjemian J, Steiner CA .
Spatial epidemiology of blastomycosis hospitalizations: detecting clusters and identifying environmental risk factors.
Med Mycol 2015 Jun;53(5):447-54. doi: 10.1093/mmy/myv014..
Keywords: Risk, Hospitalization, Elderly, Healthcare Cost and Utilization Project (HCUP)
Whicher D, Kass N, Faden R
Stakeholders' views of alternatives to prospective informed consent for minimal-risk pragmatic comparative effectiveness trials.
This paper reports on interviews with Institutional Review Board members and researchers and on focus groups with patients from Geisinger and Johns Hopkins health systems, with the objective of eliciting participants' views of the acceptability of four different disclosure and authorization models for low-risk pragmatic comparative effectiveness trials of widely-used therapies. Results suggested that many participants believed that it was acceptable to streamline information disclosure and to use an opt-out process for eligible individuals who would prefer not to participate.
AHRQ-funded; HS021064.
Citation: Whicher D, Kass N, Faden R .
Stakeholders' views of alternatives to prospective informed consent for minimal-risk pragmatic comparative effectiveness trials.
J Law Med Ethics 2015 Summer;43(2):397-409. doi: 10.1111/jlme.12256.
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Keywords: Comparative Effectiveness, Evidence-Based Practice, Patient-Centered Outcomes Research, Research Methodologies
Doucette WR, Pendergast JF, Zhang Y
Stimulating comprehensive medication reviews among Medicare Part D beneficiaries.
The authors assessed the impact of a patient engagement intervention utilizing the Medication User Self-Evaluation (MUSE) tool on the completion percentage of comprehensive medication reviews (CMRs) among Medicare Part D beneficiaries. They found that the estimated odds of having a CMR among those who received the MUSE intervention were 2 times that of their counterparts. They concluded that Part D plans could use the MUSE to engage targeted beneficiaries in using pharmacist-provided MTM services.
AHRQ-funded; HS018353.
Citation: Doucette WR, Pendergast JF, Zhang Y .
Stimulating comprehensive medication reviews among Medicare Part D beneficiaries.
Am J Manag Care 2015 Jun;21(6):e372-8.
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Keywords: Elderly, Medicare, Medication, Patient and Family Engagement, Provider: Pharmacist
Singer SJ, Jiang W, Huang LC
Surgical team member assessment of the safety of surgery practice in 38 South Carolina hospitals.
This study assessed surgical team member perceptions of multiple dimensions of safe surgical practice in 38 South Carolina hospitals participating in a statewide initiative to implement surgical safety checklists. It found that overall, 78 percent of responses were positive about surgical safety at respondent’s hospitals, but in each survey dimension, from 16 percent to 40 percent of responses were neutral/negative.
AHRQ-funded; HS019631.
Citation: Singer SJ, Jiang W, Huang LC .
Surgical team member assessment of the safety of surgery practice in 38 South Carolina hospitals.
Med Care Res Rev 2015 Jun;72(3):298-323. doi: 10.1177/1077558715577479..
Keywords: Patient Safety, Surgery, Hospitals
Kamal AH, Nipp RD, Bull J
Symptom burden and performance status among community-dwelling patients with serious illness.
The researchers explored the relationship between prevalence and severity of symptoms and underlying performance status. They found distinct groupings of symptoms with high burden associated with different levels of performance status. This includes high prevalence of fatigue, anorexia, and dyspnea in patients with high performance. Patients with low performance status, however, reported more pain, depression, and constipation.
AHRQ-funded; HS022763.
Citation: Kamal AH, Nipp RD, Bull J .
Symptom burden and performance status among community-dwelling patients with serious illness.
J Palliat Med 2015 Jun;18(6):542-4. doi: 10.1089/jpm.2014.0381..
Keywords: Patient Safety, Quality of Life, Palliative Care, Health Status
Gallagher TH, Mazor KM
Taking complaints seriously: using the patient safety lens.
This editorial defined a patient safety lens that favors learning over protection. It listed five critical components of the patient safety lens and concluded that the first and most important step entails expanding our perspective beyond the technical execution of care to encompass and appreciate patients’ reports of their care experiences.
AHRQ-funded; HS022757.
Citation: Gallagher TH, Mazor KM .
Taking complaints seriously: using the patient safety lens.
BMJ Qual Saf 2015 Jun;24(6):352-5. doi: 10.1136/bmjqs-2015-004337.
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Keywords: Healthcare Delivery, Medical Errors, Patient Safety, Patient Experience, Clinician-Patient Communication
Haywood C, Lanzkron S, Hughes M
The association of clinician characteristics with their attitudes toward patients with sickle cell disease: secondary analyses of a randomized controlled trial.
The researchers explore the extent to which clinician characteristics such as race, sex, professional discipline, and amount of exposure to sickle cell disease (SCD) patients in pain may be associated with attitudes toward SCD patients generally. They concluded that clinician attitudes toward sickle cell patients vary notably by the demographic and clinical experiences of the clinician.
AHRQ-funded; HS013903.
Citation: Haywood C, Lanzkron S, Hughes M .
The association of clinician characteristics with their attitudes toward patients with sickle cell disease: secondary analyses of a randomized controlled trial.
J Natl Med Assoc 2015 Jun;107(2):89-96..
Keywords: Sickle Cell Disease, Pain, Disparities
Resnick MJ, Barocas DA, Morgans AK
The evolution of self-reported urinary and sexual dysfunction over the last two decades: implications for comparative effectiveness research.
This study evaluated differences in pretreatment urinary and sexual function in two population-based cohorts of men with prostate cancer enrolled nearly 20 yrs. apart. It concluded that reporting of pretreatment urinary incontinence and erectile dysfunction has increased over the past two decades. These findings may reflect sociological changes including heightened media attention and direct-to-consumer marketing, among other potential explanations.
AHRQ-funded; HS019356; HS022640; HS022990.
Citation: Resnick MJ, Barocas DA, Morgans AK .
The evolution of self-reported urinary and sexual dysfunction over the last two decades: implications for comparative effectiveness research.
Eur Urol 2015 Jun;67(6):1019-25. doi: 10.1016/j.eururo.2014.08.035..
Keywords: Comparative Effectiveness, Patient-Centered Outcomes Research, Cancer, Cancer: Prostate Cancer, Sexual Health
Sommers BD, Maylone B, Nguyen KH
The impact of state policies on ACA applications and enrollment among low-income adults in Arkansas, Kentucky, and Texas.
The researchers surveyed nearly 3,000 low-income adults in late 2014 to compare experiences in three states with markedly different policies: Kentucky, Arkansas, and Texas. They found that application rates, successful enrollment, and positive experiences with the ACA were highest in Kentucky, followed by Arkansas, with Texas performing worst. Limited awareness remains a critical barrier: Fewer than half of adults had heard some or a lot about the coverage expansions.
AHRQ-funded; HS021291.
Citation: Sommers BD, Maylone B, Nguyen KH .
The impact of state policies on ACA applications and enrollment among low-income adults in Arkansas, Kentucky, and Texas.
Health Aff 2015 Jun;34(6):1010-8. doi: 10.1377/hlthaff.2015.0215..
Keywords: Policy, Low-Income, Medicaid, Health Insurance
Gibbons MB, Thompson SM, Mack RA
The relation of baseline skills to psychotherapy outcome across diverse psychotherapies.
The researchers explored the role of baseline skills deficits in compensatory skills and self-understanding across both cognitive and dynamic treatment modalities. Their results support a capitalization model for cognitive therapy but failed to support either a compensation model or a capitalization model for the short-term dynamic model.
AHRQ-funded; HS022124.
Citation: Gibbons MB, Thompson SM, Mack RA .
The relation of baseline skills to psychotherapy outcome across diverse psychotherapies.
J Clin Psychol 2015 Jun;71(6):491-9. doi: 10.1002/jclp.22165..
Keywords: Comparative Effectiveness, Depression, Behavioral Health, Outcomes, Patient-Centered Outcomes Research
Ayvaz S, Horn J, Hassanzadeh O
Toward a complete dataset of drug-drug interaction information from publicly available sources.
The researchers combined all the publicly available sources of potential drug-drug interaction information using a common data model after conducting a comprehensive and broad search. They examined the overlap between and across the data sources. Their analysis determined that there was little overlap and that there is heterogeneity between the information provided by each source.
AHRQ-funded; HS019461.
Citation: Ayvaz S, Horn J, Hassanzadeh O .
Toward a complete dataset of drug-drug interaction information from publicly available sources.
J Biomed Inform 2015 Jun;55:206-17. doi: 10.1016/j.jbi.2015.04.006..
Keywords: Medication, Patient Safety, Registries, Health Information Technology (HIT)
Weiss SM, Tobin JN, Lopez M
Translating an evidence-based behavioral intervention for women living with HIV into clinical practice: the SMART/EST Women's Program.
The researchers explored the pathways to effectively transfer promising research accomplishments into effective and sustainable service programs within the health care delivery system. Their study confirmed (a) the translatability of the Stress Management And Relaxation Training/Emotional Supportive Therapy (SMART/EST) Women's Program, from academic to community health center settings in two geographic regions with high HIV prevalence among women, (b) the ability of local staff to successfully achieve program fidelity and clinical outcomes, and (c) the sustainability the program beyond the auspices of research support, through supportive community health center leadership securing continued program funding.
AHRQ-funded; HS021667.
Citation: Weiss SM, Tobin JN, Lopez M .
Translating an evidence-based behavioral intervention for women living with HIV into clinical practice: the SMART/EST Women's Program.
Int J Behav Med 2015 Jun;22(3):415-24. doi: 10.1007/s12529-014-9399-1.
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Keywords: Behavioral Health, Evidence-Based Practice, Healthcare Delivery, Human Immunodeficiency Virus (HIV), Implementation
Francis DO, Krishnaswami S, Mcpheeters M
Treatment of ankyloglossia and breastfeeding outcomes: a systematic review.
This systematic review of literature on surgical and nonsurgical treatments for infants with ankyloglossia, a condition restricting tongue mobility in infants, found that frenotomy may be associated with mother-reported improvements in breastfeeding, and potentially in nipple pain. Since the existing studies are small and short-term with inconsistent methodology, the strength of the evidence is low to insufficient.
AHRQ-funded; 290201200009I.
Citation: Francis DO, Krishnaswami S, Mcpheeters M .
Treatment of ankyloglossia and breastfeeding outcomes: a systematic review.
Pediatrics 2015 Jun;135(6):e1458-66. doi: 10.1542/peds.2015-0658..
Keywords: Breast Feeding, Outcomes, Comparative Effectiveness, Evidence-Based Practice, Newborns/Infants
Chinnadurai S, Francis DO, Epstein RA
Treatment of ankyloglossia for reasons other than breastfeeding: a systematic review.
The researchers systematically reviewed literature on feeding, speech, and social outcomes of treatments for infants and children with ankyloglossia. After analyzing two randomized controlled trials, 2 cohort studies, and 11 case series assessing the effects of frenotomy on feeding, speech, and social outcomes, they determined that data are currently insufficient for assessing the effects of frenotomy on nonbreastfeeding outcomes that may be associated with ankyloglossia.
AHRQ-funded; 290201200009I.
Citation: Chinnadurai S, Francis DO, Epstein RA .
Treatment of ankyloglossia for reasons other than breastfeeding: a systematic review.
Pediatrics 2015 Jun;135(6):e1467-74. doi: 10.1542/peds.2015-0660..
Keywords: Breast Feeding, Children/Adolescents, Outcomes, Comparative Effectiveness
Ford E, Phillips M, Bojechko C
TU-G-BRD-08: in-vivo EPID dosimetry: quantifying the detectability of four classes of errors.
The researchers analyzed 17 patients; EPID images of the exit dose were acquired and used to reconstruct the planar dose at isocenter. Their data demonstrate the ability of EPID-based in-vivo dosimetry in detecting variations in patient habitus and errors related to machine parameters such as systematic multi-leaf collimator misalignments and machine output changes.
AHRQ-funded; HS022244.
Citation: Ford E, Phillips M, Bojechko C .
TU-G-BRD-08: in-vivo EPID dosimetry: quantifying the detectability of four classes of errors.
Med Phys 2015 Jun;42(6 Part 35):3629. doi: 10.1118/1.4925743..
Keywords: Patient Safety, Imaging, Quality of Care