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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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10726 to 10750 of 11856 Research Studies DisplayedSiddiqui M, Roberts ET, Pollack CE
The effect of emergency department copayments for Medicaid beneficiaries following the Deficit Reduction Act of 2005.
This study evaluated the effect of the 2005 Deficit Reduction Act allowing States to enforce emergency department (ED) copayments for nonurgent visits and on ED utilization among Medicaid beneficiaries. It found that granting States permission to collect copayments for nonurgent visits did not significantly change ED or outpatient medical provider use among Medicaid beneficiaries.
AHRQ-funded; HS019488
Citation: Siddiqui M, Roberts ET, Pollack CE .
The effect of emergency department copayments for Medicaid beneficiaries following the Deficit Reduction Act of 2005.
JAMA Intern Med. 2015 Mar;175(3):393-8. doi: 10.1001/jamainternmed.2014.7582..
Keywords: Emergency Department, Medicaid, Healthcare Costs
O'Leary KJ, Turner J, Christensen N
The effect of hospitalist discontinuity on adverse events.
The researchers sought to determine the association between hospital physician continuity and the incidence of adverse events (AEs). Based on an analysis including data from 474 hospitalizations, they found that hospitalist physician continuity does not appear to be associated with the incidence of AEs.
AHRQ-funded; HS019630.
Citation: O'Leary KJ, Turner J, Christensen N .
The effect of hospitalist discontinuity on adverse events.
J Hosp Med 2015 Mar;10(3):147-51. doi: 10.1002/jhm.2308..
Keywords: Patient Safety, Adverse Events, Hospitalization
Magnan EM, Palta M, Johnson HM
The impact of a patient's concordant and discordant chronic conditions on diabetes care quality measures.
The researchers sought to determine the impact of the number of concordant and discordant chronic conditions on diabetes care quality. Their findings suggest that the patients most at risk for suboptimal diabetes care are the patients with the fewest comorbidities, especially the fewest concordant comorbidities.
AHRQ-funded; HS018368; HS021899.
Citation: Magnan EM, Palta M, Johnson HM .
The impact of a patient's concordant and discordant chronic conditions on diabetes care quality measures.
J Diabetes Complications 2015 Mar;29(2):288-94. doi: 10.1016/j.jdiacomp.2014.10.003..
Keywords: Quality Measures, Diabetes, Chronic Conditions
Lynch TS, Parker RD, Patel RM
The Impact of the Multicenter Orthopaedic Outcomes Network (MOON) research on anterior cruciate ligament reconstruction and orthopaedic practice.
The Multicenter Orthopaedic Outcomes Network consortium was created in 2002 to enroll and longitudinally follow a large population cohort of anterior cruciate ligament reconstructions. The group has helped to establish a new benchmark for conducting multicenter, multisurgeon orthopaedic research. The changes in anterior cruciate ligament reconstruction practice resulting from the group include the use of autograft for high school, college, and competitive athletes.
AHRQ-funded; HS016075.
Citation: Lynch TS, Parker RD, Patel RM .
The Impact of the Multicenter Orthopaedic Outcomes Network (MOON) research on anterior cruciate ligament reconstruction and orthopaedic practice.
J Am Acad Orthop Surg 2015 Mar;23(3):154-63. doi: 10.5435/jaaos-d-14-00005..
Keywords: Surgery, Comparative Effectiveness, Patient-Centered Outcomes Research
Lee MJ, Shonnard N, Farrokhi F
The Spine Surgical Care and Outcomes Assessment Program (Spine SCOAP): a surgeon-led approach to quality and safety.
The researchers sought to identify variation in utilization, processes of care, and outcomes in spine surgery to improve statewide quality and safety. They found significant variability in the indications, process of care, and outcomes related to spine surgery. This variability indicates the need for continued surveillance initiatives and point to opportunities for quality improvement and research.
AHRQ-funded; HS020025.
Citation: Lee MJ, Shonnard N, Farrokhi F .
The Spine Surgical Care and Outcomes Assessment Program (Spine SCOAP): a surgeon-led approach to quality and safety.
Spine 2015 Mar 1;40(5):332-41. doi: 10.1097/brs.0000000000000750..
Keywords: Surgery, Quality of Care, Patient Safety, Comparative Effectiveness, Outcomes
Daubresse M, Alexander GC
The uphill battle facing antiobesity drugs.
The authors argue that the barriers faced by individual anorectic products belie larger regulatory and clinical challenges to their mainstream adoption, and contribute to the irony that despite American’s penchant for high rates of pharmaceutical use, obesity drugs have fared remarkably poorly in the market.
AHRQ-funded; HS0189960.
Citation: Daubresse M, Alexander GC .
The uphill battle facing antiobesity drugs.
Int J Obes 2015 Mar;39(3):377-8. doi: 10.1038/ijo.2014.169..
Keywords: Obesity, Medication, Obesity: Weight Management, Policy
Conover MM, Jonsson Funk M, Kinlaw AC
Trends and patterns of urodynamic studies in U.S. women, 2000-2012.
The researchers estimated utilization rates for cystometrograms and described trends in urodynamic procedures among U.S. men from 2000 to 2012. They found that urodynamic investigations were most common in men older than 65 years and increased in use and complexity over the past decade.
AHRQ-funded; HS017950.
Citation: Conover MM, Jonsson Funk M, Kinlaw AC .
Trends and patterns of urodynamic studies in U.S. women, 2000-2012.
Obstet Gynecol 2015 Mar;125(3):559-65. doi: 10.1097/aog.0000000000000641..
Keywords: Healthcare Utilization, Payment
Galbraith JW, Franco RA, Donnelly JP
Unrecognized chronic hepatitis C virus infection among baby boomers in the emergency department.
The researchers described early experience with integrated opt-out HCV antibody (Ab) screening of medically stable baby boomers presenting to an urban academic ED. They observed high prevalence of unrecognized chronic HCV infection in this series of baby boomers presenting to the ED, highlighting the ED as an important venue for high-impact HCV screening and linkage to care.
AHRQ-funded; HS013852.
Citation: Galbraith JW, Franco RA, Donnelly JP .
Unrecognized chronic hepatitis C virus infection among baby boomers in the emergency department.
Hepatology 2015 Mar;61(3):776-82. doi: 10.1002/hep.27410.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Hepatitis, Screening, Emergency Medical Services (EMS), Emergency Department
Zhang Y, Baik SH, Newhouse JP
Use of intelligent assignment to Medicare Part D plans for people with schizophrenia could produce substantial savings.
The investigators simulated Medicare Part D savings from replacing random assignment with an "intelligent assignment" algorithm that would assign beneficiaries to the least expensive plan in 2010 based on their drug usage in the previous year. They found that intelligent assignment could have saved about $150 million for Medicare and beneficiaries with schizophrenia combined in 2010.
AHRQ-funded; HS018657.
Citation: Zhang Y, Baik SH, Newhouse JP .
Use of intelligent assignment to Medicare Part D plans for people with schizophrenia could produce substantial savings.
Health Aff 2015 Mar;34(3):455-60. doi: 10.1377/hlthaff.2014.1227.
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Keywords: Healthcare Costs, Medicare, Medication, Behavioral Health
Michtalik HJ, Carolan HT, Haut ER
Use of provider-level dashboards and pay-for-performance in venous thromboembolism prophylaxis.
The researchers sequentially examined an individualized physician dashboard and pay-for-performance program to improve venous thromboembolism (VTE) prophylaxis rates among hospitalists. They found that direct feedback using dashboards was associated with significantly improved compliance, with further improvement after incorporating an individual physician pay-for-performance program.
AHRQ-funded; HS017952; HS022331.
Citation: Michtalik HJ, Carolan HT, Haut ER .
Use of provider-level dashboards and pay-for-performance in venous thromboembolism prophylaxis.
J Hosp Med 2015 Mar;10(3):172-8. doi: 10.1002/jhm.2303..
Keywords: Provider Performance, Payment, Blood Clots, Prevention, Quality Improvement, Quality of Care, Hospitals, Patient Safety
Snyder ME, Pater KS, Frail CK
Utility of a brief screening tool for medication-related problems.
The objective of this study was to estimate the psychometric properties of a brief self-administered scale as a screening tool for medication-related problems (MRPs). Its findings suggest scores on the nine-item scale are a statistically significant, although fairly modest, predictor of MRPs when controlling for other significant predictors of problems.
AHRQ-funded; HS022119.
Citation: Snyder ME, Pater KS, Frail CK .
Utility of a brief screening tool for medication-related problems.
Res Social Adm Pharm 2015 Mar-Apr;11(2):253-64. doi: 10.1016/j.sapharm.2014.08.005..
Keywords: Care Management, Community-Based Practice, Medication, Provider: Pharmacist, Screening
Hajizadeh N, Goldfeld
What happens to patients with COPD with long-term oxygen treatment who receive mechanical ventilation for COPD exacerbation? A 1-year retrospective follow-up study.
This study describes outcomes for patients with chronic obstructive pulmonary disease (COPD) on long-term oxygen treatment who are admitted to an ICU for respiratory failure and receive invasive mechanical ventilation. Of the 4,791 patients, 23 percent died in the hospital, and 45 percent died in the subsequent 12 months. Also, 67 percent of patients were readmitted at least once in the subsequent 12 months.
AHRQ-funded; HS019473.
Citation: Hajizadeh N, Goldfeld .
What happens to patients with COPD with long-term oxygen treatment who receive mechanical ventilation for COPD exacerbation? A 1-year retrospective follow-up study.
Thorax 2015 Mar;70(3):294-6. doi: 10.1136/thoraxjnl-2014-205248..
Keywords: Patient-Centered Outcomes Research, Outcomes, Comparative Effectiveness, Respiratory Conditions
Parisi LM, Gabbay RA
What providers want from the Primary Care Extension Service to facilitate practice transformation.
This 70-question survey asked 556 Pennsylvania-based primary care providers what services they want to receive from a Patient Care Extension Service, a new program being implemented under the Affordable Care Act. It found that the most desired services include (1) identifying and coordinating mental health services, (2) improving office efficiency, (3) increasing overall revenues, and (4) strategies to help implement evidence-based clinical guidelines.
AHRQ-funded; HS020988.
Citation: Parisi LM, Gabbay RA .
What providers want from the Primary Care Extension Service to facilitate practice transformation.
Fam Med 2015 Mar;47(3):210-6..
Keywords: Practice Improvement, Primary Care, Provider
Mueller EL, Sabbatini A, Gebremariam A
Why pediatric patients with cancer visit the emergency department: United States, 2006-2010.
The authors explored reasons prompting emergency department (ED) visits and factors associated with hospital admission among pediatric patients with cancer. They concluded that fever with neutropenia was the most common reason for ED visits among pediatric patients with cancer and was the condition most strongly associated with admission, and that socioeconomic factors appeared to influence ED disposition for this population.
AHRQ-funded; HS022982.
Citation: Mueller EL, Sabbatini A, Gebremariam A .
Why pediatric patients with cancer visit the emergency department: United States, 2006-2010.
Pediatr Blood Cancer 2015 Mar;62(3):490-5. doi: 10.1002/pbc.25288.
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Keywords: Cancer, Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Emergency Department, Hospitalization
Neugebauer R, Schmittdiel JA, Zhu Z
High-dimensional propensity score algorithm in comparative effectiveness research with time-varying interventions.
The authors described the application and performance of the hdPS algorithm to improve covariate selection in CER with time-varying interventions based on inverse probability weighting estimation and explored stabilization of the resulting estimates using Super Learning. Their evaluation was based on both the analysis of electronic health records data in a real-world CER study of adults with type 2 diabetes and a simulation study.
AHRQ-funded; 29020050016I.
Citation: Neugebauer R, Schmittdiel JA, Zhu Z .
High-dimensional propensity score algorithm in comparative effectiveness research with time-varying interventions.
Stat Med 2015 Feb 28;34(5):753-81. doi: 10.1002/sim.6377..
Keywords: Comparative Effectiveness, Data, Research Methodologies
Kavalieratos D, Ernecoff NC, Keim-Malpass J
Knowledge, attitudes, and preferences of healthy young adults regarding advance care planning: a focus group study of university students in Pittsburgh, USA.
This study used six focus groups consisting of 56 young adults (ages 18-30) to serve as a first step in exploring the knowledge of this population regarding advance care planning (ACP), their readiness to learn and act, and their views and needs toward this proactive health behavior. The findings suggest that 1) relatively few young adults fully understand ACP concepts, and 2) all young adults in the sample desired to learn more about ACP.
AHRQ-funded; HS022989.
Citation: Kavalieratos D, Ernecoff NC, Keim-Malpass J .
Knowledge, attitudes, and preferences of healthy young adults regarding advance care planning: a focus group study of university students in Pittsburgh, USA.
BMC Public Health 2015 Feb 27;15:197. doi: 10.1186/s12889-015-1575-y..
Keywords: Patient-Centered Outcomes Research, Education: Patient and Caregiver
Schroeder MC, Robinson JG, Chapman CG
Use of statins by Medicare beneficiaries post myocardial infarction: poor physician quality or patient-centered care?
This study assessed whether patterns of statin use by Medicare beneficiaries post-discharge may be due to a mix of high-quality and low-quality physicians. It found that the distribution of statin fill rates across physicians was normal, with no clear distinctions in physician quality. Physicians, especially cardiologists, with relatively younger and healthier patient populations had higher rates of statin use.
AHRQ-funded; HS019574.
Citation: Schroeder MC, Robinson JG, Chapman CG .
Use of statins by Medicare beneficiaries post myocardial infarction: poor physician quality or patient-centered care?
Inquiry 2015 Feb 27;52. doi: 10.1177/0046958015571131..
Keywords: Care Management, Medication, Heart Disease and Health, Medicare, Patient-Centered Healthcare, Practice Patterns
Prvu Bettger J, McCoy L, Smith EE
Contemporary trends and predictors of postacute service use and routine discharge home after stroke.
The authors examined trends in discharge to inpatient rehabilitation facilities, skilled nursing facilities, home with home health, and home without services for patients with ischemic or hemorrhagic stroke at hospitals participating in Get With The Guidelines-Stroke. They found that four in 10 stroke patients are discharged home without postacute care services. They recommended further research to explain the shift in service use by type and its effect on outcomes.
AHRQ-funded; HS019479.
Citation: Prvu Bettger J, McCoy L, Smith EE .
Contemporary trends and predictors of postacute service use and routine discharge home after stroke.
J Am Heart Assoc 2015 Feb 23;4(2). doi: 10.1161/jaha.114.001038.
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Keywords: Critical Care, Hospital Discharge, Home Healthcare, Stroke
Samwald M, Minarro Gimenez JA, Boyce RD
Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies.
The authors developed Web Ontology Language (OWL) ontologies and automated reasoning methodologies to meet various goals such as providing a simple and concise formalism for representing pharmacogenomic knowledge. Their ontology-based framework can be used to represent, organize and reason over the growing wealth of pharmacogenomic knowledge, as well as to identify errors, inconsistencies and insufficient definitions in source data sets or individual patient data.
AHRQ-funded; HS019461.
Citation: Samwald M, Minarro Gimenez JA, Boyce RD .
Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies.
BMC Med Inform Decis Mak 2015 Feb 22;15:12. doi: 10.1186/s12911-015-0130-1..
Keywords: Comparative Effectiveness, Health Information Technology (HIT), Decision Making, Medication, Genetics
Jones JB, Weiner JP, Shah NR
The wired patient: patterns of electronic patient portal use among patients with cardiac disease or diabetes.
The researchers described the types and patterns of portal users in an integrated delivery system. They found naturally occurring groups of EHR Web portal users within a population of adult primary care patients with chronic conditions. More than half of the patient cohort exhibited distinct patterns of portal use linked to key features.
AHRQ-funded; HS016228.
Citation: Jones JB, Weiner JP, Shah NR .
The wired patient: patterns of electronic patient portal use among patients with cardiac disease or diabetes.
J Med Internet Res 2015 Feb 20;17(2):e42. doi: 10.2196/jmir.3157..
Keywords: Health Information Technology (HIT), Electronic Health Records (EHRs), Primary Care, Healthcare Delivery, Chronic Conditions
Li T, Vedula SS, Hadar N
Innovations in data collection, management, and archiving for systematic reviews.
The authors provide a step-by-step tutorial for collecting, managing, and archiving data for systematic reviews and suggest steps for developing rigorous data collection forms in the Systematic Review Data Repository to facilitate implementation of the methodological standards and expectations of the Institute of Medicine and other organizations.
AHRQ-funded; 290200710055I; 290201200012I.
Citation: Li T, Vedula SS, Hadar N .
Innovations in data collection, management, and archiving for systematic reviews.
Ann Intern Med. 2015 Feb 17;162(4):287-94. doi: 10.7326/M14-1603..
Keywords: Data, Comparative Effectiveness, Outcomes, Research Methodologies
Linder JA
Sore throat: avoid overcomplicating the uncomplicated.
In this editorial, the author described issues involving sore throat diagnosis and delineated various points concerning an article within the same journal issue, concluding that physicians should remember that the prevalence of group A streptococcus in adults with a sore throat is approximately 10%; and that they should use the Centor scoring criteria; selectively use rapid antigen-detection testing; limit antibiotic treatment to patients most likely to have group A streptococcus; and most of the time when prescribing antibiotics, use penicillin.
AHRQ-funded; HS018419.
Citation: Linder JA .
Sore throat: avoid overcomplicating the uncomplicated.
Ann Intern Med 2015 Feb 17;162(4):311-2. doi: 10.7326/m14-2899.
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Keywords: Antibiotics, Diagnostic Safety and Quality, Infectious Diseases, Medication, Pneumonia, Respiratory Conditions, Practice Patterns
Chou R, Turner JA, Devine EB
The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institutes of Health Pathways to Prevention Workshop.
This systematic review evaluated evidence on the effectiveness and harms of long-term (more than 3 months) opiod therapy for chronic pain in adults. It concluded that evidence is insufficient to determine the effectiveness of this therapy for improving chronic pain and function.
AHRQ-funded; 290201200014I
Citation: Chou R, Turner JA, Devine EB .
The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institutes of Health Pathways to Prevention Workshop.
Ann Intern Med. 2015 Feb 17;162(4):276-86. doi: 10.7326/M14-2559..
Keywords: Chronic Conditions, Comparative Effectiveness, Medication, Opioids, Outcomes, Pain, Patient-Centered Outcomes Research
Wang HE, Addis DR, Donnelly JP
Discharge diagnoses versus medical record review in the identification of community-acquired sepsis.
The researchers evaluated the accuracy of hospital discharge diagnoses in the identification of community-acquired sepsis and severe sepsis. They found that hospital discharge diagnoses show good specificity but poor sensitivity for detecting community-acquired sepsis and severe sepsis.
AHRQ-funded; HS013852.
Citation: Wang HE, Addis DR, Donnelly JP .
Discharge diagnoses versus medical record review in the identification of community-acquired sepsis.
Crit Care 2015 Feb 16;19:42. doi: 10.1186/s13054-015-0771-6.
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Keywords: Community-Acquired Infections, Diagnostic Safety and Quality, Hospital Discharge, Sepsis
Althoff KN, McGinnis KA, Wyatt CM
Comparison of risk and age at diagnosis of myocardial infarction, end-stage renal disease, and non-AIDS-defining cancer in HIV-infected versus uninfected adults.
The objective of this study was to compare the median age at, and risk of, incident diagnosis of 3 age-associated diseases in HIV-infected and demographically similar uninfected adults. It found that HIV-infected adults had a higher risk of these age-associated diseases (myocardial infarction, end-stage renal disease, and non-AIDS-defining cancer), but they occurred at similar ages to those without HIV.
AHRQ-funded; HS018372.
Citation: Althoff KN, McGinnis KA, Wyatt CM .
Comparison of risk and age at diagnosis of myocardial infarction, end-stage renal disease, and non-AIDS-defining cancer in HIV-infected versus uninfected adults.
Clin Infect Dis 2015 Feb 15;60(4):627-38. doi: 10.1093/cid/ciu869..
Keywords: Human Immunodeficiency Virus (HIV), Heart Disease and Health, Kidney Disease and Health, Cancer
