National Healthcare Quality and Disparities Report
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Topics
- Adverse Drug Events (ADE) (1)
- Adverse Events (1)
- Antibiotics (1)
- Asthma (1)
- Behavioral Health (2)
- Breast Feeding (1)
- Cancer (1)
- Cancer: Breast Cancer (1)
- Cardiovascular Conditions (1)
- Caregiving (1)
- Care Management (2)
- Children/Adolescents (15)
- Chronic Conditions (1)
- Clinical Decision Support (CDS) (2)
- Clinician-Patient Communication (2)
- Communication (2)
- Community-Based Practice (2)
- Comparative Effectiveness (2)
- Depression (1)
- Diabetes (5)
- Diagnostic Safety and Quality (1)
- Digestive Disease and Health (1)
- Education: Continuing Medical Education (1)
- Education: Patient and Caregiver (3)
- Elderly (3)
- Electronic Health Records (EHRs) (2)
- Evidence-Based Practice (1)
- Family Health and History (2)
- Guidelines (1)
- Healthcare-Associated Infections (HAIs) (1)
- Healthcare Costs (1)
- Health Information Technology (HIT) (5)
- Health Insurance (1)
- Health Literacy (1)
- Health Promotion (2)
- Health Status (3)
- Human Immunodeficiency Virus (HIV) (1)
- Implementation (1)
- Lifestyle Changes (6)
- Maternal Care (1)
- Medical Expenditure Panel Survey (MEPS) (1)
- Medicare (1)
- Medication (3)
- Newborns/Infants (1)
- Nutrition (8)
- (-) Obesity (43)
- Obesity: Weight Management (7)
- Outcomes (2)
- Patient-Centered Outcomes Research (3)
- Patient Adherence/Compliance (1)
- Patient Experience (1)
- Policy (2)
- Pregnancy (2)
- Prevention (7)
- Primary Care (3)
- Public Health (1)
- Quality Improvement (1)
- Quality of Life (1)
- Racial and Ethnic Minorities (5)
- Research Methodologies (1)
- Risk (3)
- Social Determinants of Health (2)
- Social Stigma (1)
- Surgery (5)
- Telehealth (1)
- Tobacco Use (3)
- Web-Based (1)
- Women (4)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 25 of 43 Research Studies DisplayedDarling KE, Warnick J, Guerry WB
Adolescent females' dyadic conversations about body, weight, and appearance.
The purpose of this observational study was to examine body talk between adolescent female dyads aged 13-17. Reciprocally nominated dyads were recruited from a southeastern US high school. Themes that emerged were related to weight, appearance, and personality. The authors concluded that their results provided insight into the social context in which sociocultural norms of weight stigma, body dissatisfaction, and eating-related psychopathology may be reinforced, and that these findings have implications for informing the development of interventions to reduce negative weight- and appearance-related body talk among adolescent girls.
AHRQ-funded; HS027071.
Citation: Darling KE, Warnick J, Guerry WB .
Adolescent females' dyadic conversations about body, weight, and appearance.
J Adolesc Res 2024 Mar; 39(2):487-510. doi: 10.1177/07435584221120111.
Keywords: Children/Adolescents, Obesity, Social Stigma
Sneed NM, Heerman WJ, Shaw PA
Associations between gestational weight gain, gestational diabetes, and childhood obesity incidence.
Excessive maternal gestational weight gain (GWG) and gestational diabetes mellitus (GDM) have been linked to childhood obesity. This cohort study explored the association between maternal weight gain during pregnancy, GDM, and early childhood obesity. Findings revealed that excessive weight gain during the second and third trimesters increased the risk of childhood obesity by age 6. However, GDM was associated with a lower risk. No significant interaction between GWG and GDM was observed.
AHRQ-funded; HS026122.
Citation: Sneed NM, Heerman WJ, Shaw PA .
Associations between gestational weight gain, gestational diabetes, and childhood obesity incidence.
Matern Child Health J 2024 Feb; 28(2):372-81. doi: 10.1007/s10995-023-03853-8.
Keywords: Maternal Care, Women, Children/Adolescents, Obesity
Liu S, Matvekas A, Naimi T
Morphomics-informed population pharmacokinetic and physiologically-based pharmacokinetic modeling to optimize cefazolin surgical prophylaxis.
This study’s objective was to use algorithms that repurpose radiologic data into body composition (morphomics) to aid in informing dosing decisions for the antibiotic cefazolin for patients undergoing colorectal surgery who have obesity. This prospective study measured cefazolin plasma, fat, and colon tissue concentrations in these patients to develop a morphomics-informed population pharmacokinetic (PopPK) model to guide dose adjustments. A physiologically-based pharmacokinetic (PBPK) model was also constructed to inform tissue partitioning in 21 morbidly obese patients (body mass index ≥35 kg/m2 with one or more co-morbid conditions). Morphomics and pharmacokinetic data were available in 58 patients with a median weight of 95.9 kg and and 55 years, respectively. The plasma-to-subcutaneous fat partition coefficient was predicted to be 0.072 for the PopPK model and 0.060 for the PBPK model. Covariates of cefazolin exposure were identified as the estimated creatinine clearance (eCL(cr) ) and body depth at the third lumbar vertebra (body depth_L3). The authors concluded that kidney function and morphomics were more informative than body weight as covariates of cefazolin target site exposure. They advised that data from more diverse populations, consensus on target cefazolin exposure, and comparative studies are needed before a change in practice can be implemented.
AHRQ-funded; HS027183.
Citation: Liu S, Matvekas A, Naimi T .
Morphomics-informed population pharmacokinetic and physiologically-based pharmacokinetic modeling to optimize cefazolin surgical prophylaxis.
Pharmacotherapy 2024 Jan; 44(1):77-86. doi: 10.1002/phar.2878..
Keywords: Surgery, Antibiotics, Medication, Prevention, Obesity, Healthcare-Associated Infections (HAIs)
Boles RE, Yun L, Hambidge SJ, et al.
Influencing the home food and activity environment of families of preschool children receiving home-based treatment for obesity.
The goal of this study was to characterize the home food and activity environments of overweight and obese preschool-aged children from low socioeconomic status Latino families. It showed that despite a small, but significant reduction in preschool BMI for a subsample, families showed little change in the home food and activity environment.
AHRQ-funded; HS021138.
Citation: Boles RE, Yun L, Hambidge SJ, et al..
Influencing the home food and activity environment of families of preschool children receiving home-based treatment for obesity.
Clin Pediatr 2015 Dec;54(14):1387-90. doi: 10.1177/0009922815570614..
Keywords: Obesity, Children/Adolescents, Nutrition, Obesity: Weight Management, Family Health and History
Batsis JA, Mackenzie TA, Lopez-Jimenez F
Sarcopenia, sarcopenic obesity, and functional impairments in older adults: National Health and Nutrition Examination Surveys 1999-2004.
The researchers tested the hypothesis that the prevalence of sarcopenia and sarcopenic obesity would be similar based on the different NIH criteria, increase with age, and be associated with risk of impairment limitations. They concluded that the prevalence of sarcopenia and sarcopenic obesity varies greatly, and a uniform definition is needed to identify and characterize these high-risk populations.
AHRQ-funded; HS021695.
Citation: Batsis JA, Mackenzie TA, Lopez-Jimenez F .
Sarcopenia, sarcopenic obesity, and functional impairments in older adults: National Health and Nutrition Examination Surveys 1999-2004.
Nutr Res 2015 Dec;35(12):1031-9. doi: 10.1016/j.nutres.2015.09.003.
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Keywords: Elderly, Obesity, Chronic Conditions, Health Status
Grenda TR, Pradarelli JC, Thumma JR
Variation in hospital episode costs with bariatric surgery.
This study examined hospital variation in episode costs for a common high-risk procedure that is a prime candidate for bundled payment programs (ie, bariatric surgery). It found that mean total payments for bariatric procedures varied from $11,086 to $13,073 per episode of care, resulting in a mean difference of $1,987 (16.5 percent difference) per episode of care between the lowest and highest hospital quartiles.
AHRQ-funded; HS000053.
Citation: Grenda TR, Pradarelli JC, Thumma JR .
Variation in hospital episode costs with bariatric surgery.
JAMA Surg 2015 Dec;150(12):1109-15. doi: 10.1001/jamasurg.2015.2394.
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Keywords: Surgery, Obesity, Healthcare Costs
Taveras EM, Marshall R, Sharifi M
Connect for Health: Design of a clinical-community childhood obesity intervention testing best practices of positive outliers.
The Connect for Health study is designed to assess whether a novel approach to care delivery that leverages clinical and community resources and addresses socio-contextual factors will improve body mass index and family-centered, obesity-related outcomes of interest to parents and children. The intervention is informed by clinical, community, parent, and youth stakeholders and incorporates successful strategies and best practices learned from 'positive outlier' families.
AHRQ-funded; HS022986.
Citation: Taveras EM, Marshall R, Sharifi M .
Connect for Health: Design of a clinical-community childhood obesity intervention testing best practices of positive outliers.
Contemp Clin Trials 2015 Nov;45(Pt B):287-95. doi: 10.1016/j.cct.2015.09.022.
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Keywords: Children/Adolescents, Obesity, Health Information Technology (HIT), Community-Based Practice, Patient-Centered Outcomes Research
Sharifi M, Marshall G, Goldman RE
Engaging children in the development of obesity interventions: exploring outcomes that matter most among obesity positive outliers.
The researchers explored outcomes and measures of success that matter most to 'positive outlier' children who improved their body mass index (BMI) despite living in obesogenic neighborhoods. They found that children identified bullying and negative peer comparisons related to physical appearance, clothing size, and athletic ability as motivating them to achieve a healthier weight, and they measured success as improvement in these domains. Positive relationships with friends and family facilitated both behavior change initiation and maintenance.
AHRQ-funded; HS022986.
Citation: Sharifi M, Marshall G, Goldman RE .
Engaging children in the development of obesity interventions: exploring outcomes that matter most among obesity positive outliers.
Patient Educ Couns 2015 Nov;98(11):1393-401. doi: 10.1016/j.pec.2015.06.007.
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Keywords: Children/Adolescents, Obesity, Family Health and History, Lifestyle Changes, Patient-Centered Outcomes Research
Mansi I, Frei CR, Wang CP
Statins and new-onset diabetes mellitus and diabetic complications: a retrospective cohort study of US healthy adults.
The authors studied the long-term relationship between statin use and new-onset diabetes among Tricare beneficiaries. They found that diabetes, diabetic complications, and overweight/obesity were more commonly diagnosed among statin-users than similar nonusers in a healthy cohort of adults, demonstrating that short-term clinical trials might not fully describe the risk/benefit of long-term statin use for primary prevention.
AHRQ-funded; HS022418.
Citation: Mansi I, Frei CR, Wang CP .
Statins and new-onset diabetes mellitus and diabetic complications: a retrospective cohort study of US healthy adults.
J Gen Intern Med 2015 Nov;30(11):1599-610. doi: 10.1007/s11606-015-3335-1.
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Keywords: Adverse Drug Events (ADE), Diabetes, Medication, Obesity
Kenzik KM, Morey MC, Cohen HJ
Symptoms, weight loss, and physical function in a lifestyle intervention study of older cancer survivors.
This study examined how overweight long-term survivors’ symptom severity associated with comorbidity prior to a diet and exercise intervention was associated with post-intervention function. It found that symptom severity of older, overweight cancer survivors negatively affects physical function. However, greater weight loss and more physical activity were associated with higher functioning scores, regardless of symptom severity.
AHRQ-funded; HS013852.
Citation: Kenzik KM, Morey MC, Cohen HJ .
Symptoms, weight loss, and physical function in a lifestyle intervention study of older cancer survivors.
J Geriatr Oncol 2015 Nov;6(6):424-32. doi: 10.1016/j.jgo.2015.08.004..
Keywords: Cancer, Elderly, Obesity, Nutrition
Waljee JF, Ghaferi A, Finks JF
Variation in patient-reported outcomes across hospitals following surgery.
The researchers examined variation in patient-reported outcomes (PROs), specifically health-related quality of life (HRQOL), across hospitals performing bariatric surgery. They found that patient factors explain a large proportion of hospital-level variation in PROs following bariatric surgery, underscoring the importance of risk adjustment.
AHRQ-funded; HS023313.
Citation: Waljee JF, Ghaferi A, Finks JF .
Variation in patient-reported outcomes across hospitals following surgery.
Med Care 2015 Nov;53(11):960-6. doi: 10.1097/mlr.0000000000000425..
Keywords: Quality of Life, Surgery, Obesity, Patient-Centered Outcomes Research, Patient Experience
Horner-Johnson W, Dobbertin K, Kulkarni-Rajasekhara S
Food insecurity, hunger, and obesity among informal caregivers.
Increasing numbers of US residents rely on informal caregiving from friends and family members. Caregiving can have substantial health and financial impacts on caregivers. This study addressed whether those impacts include adverse nutritional states. It concluded that caregiving is associated with increased risk of food insecurity and hunger in Oregon.
AHRQ-funded; HS022981.
Citation: Horner-Johnson W, Dobbertin K, Kulkarni-Rajasekhara S .
Food insecurity, hunger, and obesity among informal caregivers.
Prev Chronic Dis 2015 Oct 8;12:E170. doi: 10.5888/pcd12.150129..
Keywords: Caregiving, Obesity, Nutrition, Health Status
Yawn BP, Rank MA, Bertram SL
Obesity, low levels of physical activity and smoking present opportunities for primary care asthma interventions: an analysis of baseline data from the asthma tools study.
The researchers calculated cross-sectional frequencies of activity levels, smoking, secondhand smoke exposure and the presence of obesity, as well as rates of out-of-control asthma and asthma exacerbations. They found that tobacco smoke exposure, obesity, low activity levels, poverty, inadequately controlled asthma and high asthma-related health-care utilization were common. Across all age groups, obesity was associated with poorer asthma outcomes.
AHRQ-funded; HS018431.
Citation: Yawn BP, Rank MA, Bertram SL .
Obesity, low levels of physical activity and smoking present opportunities for primary care asthma interventions: an analysis of baseline data from the asthma tools study.
NPJ Prim Care Respir Med 2015 Oct 1;25:15058. doi: 10.1038/npjpcrm.2015.58..
Keywords: Asthma, Obesity, Tobacco Use, Primary Care, Outcomes
Abdus S, Zuvekas SH
AHRQ Author: Abdus S, Zuvekas SH
Racial/ethnic differences in the relationship between obesity and depression treatment.
This study examined the relationship between obesity and the treatment of depression across racial/ethnic subgroups, controlling for depressive symptoms, self-rated mental health, health status, and socioeconomic characteristics. It found that the association between obesity and depression-related medication was significant for white women but not for black or Hispanic women. The results for men were, in general, mixed and inconsistent.
AHRQ-authored.
Citation: Abdus S, Zuvekas SH .
Racial/ethnic differences in the relationship between obesity and depression treatment.
J Behav Health Serv Res 2015 Oct;42(4):486-503. doi: 10.1007/s11414-014-9391-1..
Keywords: Obesity, Depression, Social Determinants of Health, Racial and Ethnic Minorities, Medical Expenditure Panel Survey (MEPS)
Gance-Cleveland B, Aldrich H, Dandreaux D
A virtual childhood obesity collaborative: satisfaction with online continuing education.
This descriptive study evaluated school-based health center (SBHC) providers’ satisfaction with Web based continuing education as part of a virtual childhood obesity intervention. Participation in the first two learning sessions was higher than the last two. Provider satisfaction of training modules by question type and content area was quite high. Many providers also reported plans to make changes in their practice after completing the training.
AHRQ-funded; HS018646.
Citation: Gance-Cleveland B, Aldrich H, Dandreaux D .
A virtual childhood obesity collaborative: satisfaction with online continuing education.
J Pediatr Health Care 2015 Sep-Oct;29(5):413-23. doi: 10.1016/j.pedhc.2015.01.006..
Keywords: Education: Continuing Medical Education, Obesity, Children/Adolescents, Prevention, Web-Based
Pu J, Zhao B, Wang EJ
Racial/ethnic differences in gestational diabetes prevalence and contribution of common risk factors.
This study aimed to assess racial/ethnic differences in relative contribution of risk factors of gestational diabetes mellitus (GDM) among Asian subgroups (Asian Indian, Chinese, Filipino, Japanese, Korean, and Vietnamese), Hispanics, non-Hispanic blacks, and non-Hispanic whites. It found that GDM was most prevalent among Asian Indians (19.3 percent). Relative risks were similar across all race/ethnic groups.
AHRQ-funded; HS019815.
Citation: Pu J, Zhao B, Wang EJ .
Racial/ethnic differences in gestational diabetes prevalence and contribution of common risk factors.
Paediatr Perinat Epidemiol 2015 Sep;29(5):436-43. doi: 10.1111/ppe.12209.
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Keywords: Diabetes, Obesity, Pregnancy, Racial and Ethnic Minorities, Risk, Women
Gill LE, Bartels SJ, Batsis JA
Weight management in older adults.
This overview highlights the challenges and implications of measuring adiposity in older adults and the dangers and benefits of weight loss in this population and provides an overview of the new Medicare Obesity Benefit. In addition, it provide a summary of outcomes from successful weight loss interventions for older adults and discuss implications for advancing clinical practice.
AHRQ-funded; HS0217695.
Citation: Gill LE, Bartels SJ, Batsis JA .
Weight management in older adults.
Curr Obes Rep 2015 Sep;4(3):379-88. doi: 10.1007/s13679-015-0161-z.
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Keywords: Elderly, Obesity: Weight Management, Obesity, Medicare
Chung CF, Cook K, Bales E
More than telemonitoring: Health provider use and nonuse of life-log data in irritable bowel syndrome and weight management.
The researchers sought to develop an in-depth understanding of providers’ facilitators and barriers to successfully integrating life-log data into their practices and creating better experiences. Providers reported using self-monitoring data to enhance provider-patient communication, develop personalized treatment plans, and to motivate and educate patients, in addition to using them as diagnostic and adherence tools. Barriers included a lack of time to review detailed records and questions about providers' expertise to review it.
AHRQ-funded; HS023654.
Citation: Chung CF, Cook K, Bales E .
More than telemonitoring: Health provider use and nonuse of life-log data in irritable bowel syndrome and weight management.
J Med Internet Res 2015 Aug 21;17(8):e203. doi: 10.2196/jmir.4364..
Keywords: Digestive Disease and Health, Health Information Technology (HIT), Telehealth, Obesity, Clinician-Patient Communication
Dugan TM, Mukhopadhyay S, Carroll A
Machine learning techniques for prediction of early childhood obesity.
This study aimed to predict childhood obesity after age two, using only data collected prior to the second birthday by a clinical decision support system called CHICA. It demonstrated that data from a production clinical decision support system can be used to build an accurate machine learning model to predict obesity in children after age two.
AHRQ-funded; HS020640; HS018453; HS017939.
Citation: Dugan TM, Mukhopadhyay S, Carroll A .
Machine learning techniques for prediction of early childhood obesity.
Appl Clin Inform 2015 Aug 12;6(3):506-20. doi: 10.4338/aci-2015-03-ra-0036.
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Keywords: Children/Adolescents, Obesity, Health Information Technology (HIT), Clinical Decision Support (CDS), Children/Adolescents
Kurtz MP, McNamara ER, Schaeffer AJ
Association of BMI and pediatric urologic postoperative events: results from pediatric NSQIP.
The researchers sought to determine the association of elevated BMI with overall 30-day postoperative events and wound complications in a large national sample of children undergoing urologic procedures. They concluded that BMI in the pediatric National Surgical Quality Improvement Program urologic population was found to be associated with overall complication after adjustment for case type and preoperative comorbidity.
AHRQ-funded; HS000063.
Citation: Kurtz MP, McNamara ER, Schaeffer AJ .
Association of BMI and pediatric urologic postoperative events: results from pediatric NSQIP.
J Pediatr Urol 2015 Aug;11(4):224.e1-6. doi: 10.1016/j.jpurol.2015.04.014..
Keywords: Surgery, Children/Adolescents, Obesity, Risk, Adverse Events
Baer HJ, Wee CC, DeVito K
Design of a cluster-randomized trial of electronic health record-based tools to address overweight and obesity in primary care.
The researchers described the design of a trial to examine the effectiveness of electronic health record-based tools for the assessment and management of overweight and obesity among adult primary care patients, as well as the challenges encountered. New features included reminders to measure height and weight, and an alert asking providers to add overweight or obesity to the problem list.
AHRQ-funded; HS019789.
Citation: Baer HJ, Wee CC, DeVito K .
Design of a cluster-randomized trial of electronic health record-based tools to address overweight and obesity in primary care.
Clin Trials 2015 Aug;12(4):374-83. doi: 10.1177/1740774515578132..
Keywords: Health Information Technology (HIT), Primary Care, Obesity, Electronic Health Records (EHRs), Clinician-Patient Communication
Bertrand KA, Baer HJ, Orav EJ
Body fatness during childhood and adolescence and breast density in young women: a prospective analysis.
The authors examined associations of early life body fatness with adult breast density in 182 women in the Dietary Intervention Study in Children (DISC) who were ages 25-29 at follow-up. Their results support the hypothesis that body fatness during childhood and adolescence may play an important role in premenopausal breast density, independent of current BMI, and further suggest direct or indirect influences on absolute dense breast volume.
AHRQ-funded; HS019789.
Citation: Bertrand KA, Baer HJ, Orav EJ .
Body fatness during childhood and adolescence and breast density in young women: a prospective analysis.
Breast Cancer Res 2015 Jul 16;17:95. doi: 10.1186/s13058-015-0601-4.
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Keywords: Cancer: Breast Cancer, Children/Adolescents, Obesity, Women
Shaikh U, Romano P, Paterniti DA
Organizing for quality improvement in health care: An example from childhood obesity prevention.
The researchers evaluated how the quality improvement (QI) intervention, Healthy Eating Active Living TeleHealth Community of Practice, at 7 rural California clinics addressed the challenges. of preventing and managing obesity and translation of evidence into practice. Key challenges were clinician and staff buy-in, changing ingrained clinical practices, and motivating patient and families. Facilitators included top-down organizational requirements for QI, linkages to local QI resources, and involvement of clinical champions.
AHRQ-funded; HS018567.
Citation: Shaikh U, Romano P, Paterniti DA .
Organizing for quality improvement in health care: An example from childhood obesity prevention.
Qual Manag Health Care 2015 Jul-Sep;24(3):121-8. doi: 10.1097/qmh.0000000000000066.
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Keywords: Quality Improvement, Children/Adolescents, Obesity, Prevention, Primary Care
Wang Y, Cai L, Wu Y
What childhood obesity prevention programmes work? A systematic review and meta-analysis.
The researchers systematically evaluated the effectiveness of childhood obesity prevention programs conducted in high-income countries and implemented in various settings. Their review found at least moderately strong evidence supporting the effectiveness of school-based interventions involving physical activity, diet or combined diet and physical activity for preventing childhood obesity.
AHRQ-funded; 290200710061I.
Citation: Wang Y, Cai L, Wu Y .
What childhood obesity prevention programmes work? A systematic review and meta-analysis.
Obes Rev 2015 Jul;16(7):547-65. doi: 10.1111/obr.12277..
Keywords: Children/Adolescents, Comparative Effectiveness, Obesity, Prevention
Lewis ZH, Lyons EJ, Jarvis JM
Using an electronic activity monitor system as an intervention modality: a systematic review.
The authors aimed to synthesize the efficacy and feasibility results of electronic activity monitor systems (EAMSs) within published physical activity interventions. They found preliminary evidence suggesting that EAMS can increase physical activity and decrease weight significantly, but their efficacy compared to other interventions has not yet been demonstrated.
AHRQ-funded; HS022134.
Citation: Lewis ZH, Lyons EJ, Jarvis JM .
Using an electronic activity monitor system as an intervention modality: a systematic review.
BMC Public Health 2015 Jun 24;15:585. doi: 10.1186/s12889-015-1947-3.
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Keywords: Diabetes, Health Promotion, Lifestyle Changes, Obesity