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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedChen Y, Lopman BA, Hall AJ
Factors driving norovirus transmission in long-term care facilities: a case-level analysis of 107 outbreaks.
Norovirus stands as the leading cause of gastroenteritis outbreaks in long-term care facilities (LTCFs) throughout the United States, resulting in significant disease impact on both residents and employees. The purpose of this study was to gain insight into the symptoms and features of individual cases that influence norovirus transmission can enhance the implementation of outbreak management strategies in LTCFs. In this study, the researchers analyzed line lists from 107 norovirus outbreaks occurring in LTCFs across five U.S. states between 2015 and 2019. The individual effective reproduction number, R(i), was calculated to determine the infectiousness of each case, while exploring the influence of vomiting, diarrhea, and being a resident (as opposed to staff) on case infectiousness. The study found that cases involving vomiting led to 1.28 times more secondary infections than those without vomiting, while LTCF residents caused 1.31 times more secondary infections than staff members. No significant difference in infectiousness was observed between cases with and without diarrhea.
AHRQ-funded; HS025987
Citation: Chen Y, Lopman BA, Hall AJ .
Factors driving norovirus transmission in long-term care facilities: a case-level analysis of 107 outbreaks.
Epidemics 2023 Mar;42:100671. doi: 10.1016/j.epidem.2023.100671.
Keywords: Long-Term Care, Infectious Diseases