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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 10 of 10 Research Studies DisplayedRosas LG, Lv N, Xiao L
Effect of a culturally adapted behavioral intervention for Latino adults on weight loss over 2 years: a randomized clinical trial.
Identifying effective weight loss interventions for Latino adults at risk of diabetes is of critical public health importance. The purpose of this study was to determine whether a culturally adapted behavioral intervention for Latino adults was more effective than usual care for weight loss over 24 months. The investigators concluded that among Latino adults with high diabetes risk, a culturally adapted behavioral lifestyle intervention was effective for weight loss over 12 months but not 24 months.
AHRQ-funded; HS022702.
Citation: Rosas LG, Lv N, Xiao L .
Effect of a culturally adapted behavioral intervention for Latino adults on weight loss over 2 years: a randomized clinical trial.
JAMA Netw Open 2020 Dec;3(12):e2027744. doi: 10.1001/jamanetworkopen.2020.27744..
Keywords: Racial and Ethnic Minorities, Obesity: Weight Management, Obesity, Cultural Competence, Diabetes, Primary Care, Outcomes, Patient-Centered Outcomes Research, Comparative Effectiveness, Evidence-Based Practice
Presley C, Agne A, Shelton T
Mobile-enhanced peer support for African Americans with Type 2 diabetes: a randomized controlled trial.
This study compared the effectiveness of a community-based diabetes self-management education (DSME) plus mobile health (mHealth)-enhanced peer support intervention to community-based DSME alone for African American adults with poorly controlled type 2 diabetes. This randomized controlled trial took place in Jefferson County, Alabama within a safety-net healthcare system with a group diagnosed with type 2 diabetes and hemoglobin A1C ≥ 7.5%. The intervention group reviewed community-based DSME plus 6 months of mHealth-enhanced peer support, including 12 weekly phone calls, then 3 monthly calls from community health workers. The control group received community based DSME only. Primary outcomes were lower A1C and secondary outcomes were lower diabetes distress, depressive symptoms, self-efficacy or confidence in their ability to manage diabetes, and social support. Of 120 participants selected, 97 completed the study. Both groups experienced clinical meaning reduction in A1C. Participants in the intervention group experienced a significantly larger reduction in diabetes distress compared to the control group.
AHRQ-funded; HS019465.
Citation: Presley C, Agne A, Shelton T .
Mobile-enhanced peer support for African Americans with Type 2 diabetes: a randomized controlled trial.
J Gen Intern Med 2020 Oct;35(10):2889-96. doi: 10.1007/s11606-020-06011-w..
Keywords: Telehealth, Health Information Technology (HIT), Patient Self-Management, Diabetes, Chronic Conditions, Racial and Ethnic Minorities, Community-Based Practice, Comparative Effectiveness, Patient-Centered Outcomes Research, Evidence-Based Practice, Outcomes, Education: Patient and Caregiver
Burnett-Zeigler I, Hong S, Waldron EM
A mindfulness-based intervention for low-income African American women with depressive symptoms delivered by an experienced instructor versus a novice instructor.
The authors piloted a streamlined mindfulness teacher training protocol for Federally Qualified Health Center (FQHC) staff. They also examined the distribution and variability of psychologic outcomes for participants in groups led by an experienced instructor compared to a FQHC staff instructor who received the streamlined training. They concluded that preliminary data indicate that health care staff who receive streamlined training to deliver mindfulness-based interventions have comparable outcomes as experienced instructors.
AHRQ-funded; HS023011.
Citation: Burnett-Zeigler I, Hong S, Waldron EM .
A mindfulness-based intervention for low-income African American women with depressive symptoms delivered by an experienced instructor versus a novice instructor.
J Altern Complement Med 2019 Jul;25(7):699-708. doi: 10.1089/acm.2018.0393..
Keywords: Behavioral Health, Comparative Effectiveness, Depression, Low-Income, Outcomes, Patient-Centered Outcomes Research, Racial and Ethnic Minorities, Vulnerable Populations, Training, Women
Singal AG, Tiro JA, Murphy CC
Mailed outreach invitations significantly improve HCC surveillance rates in patients with cirrhosis: a randomized clinical trial.
Mailed outreach invitations significantly improve HCC surveillance rates in patients with cirrhosis: a randomized clinical trial.
Hepatology 2019 Jan;69(1):121-30. doi: 10.1002/hep.30129.
In this study, the investigators compared the effectiveness of mailed outreach and patient navigation strategies to increase hepatocellular carcinoma (HCC) surveillance in a racially diverse cohort of patients with cirrhosis. They conducted a pragmatic randomized clinical trial comparing mailed outreach for screening ultrasound, mailed outreach plus patient navigation, or usual care with visit-based screening. The investigators concluded that mailed outreach invitations and navigation significantly increased HCC surveillance versus usual care in patients with cirrhosis.
Hepatology 2019 Jan;69(1):121-30. doi: 10.1002/hep.30129.
In this study, the investigators compared the effectiveness of mailed outreach and patient navigation strategies to increase hepatocellular carcinoma (HCC) surveillance in a racially diverse cohort of patients with cirrhosis. They conducted a pragmatic randomized clinical trial comparing mailed outreach for screening ultrasound, mailed outreach plus patient navigation, or usual care with visit-based screening. The investigators concluded that mailed outreach invitations and navigation significantly increased HCC surveillance versus usual care in patients with cirrhosis.
AHRQ-funded; HS022418.
Citation: Singal AG, Tiro JA, Murphy CC .
Mailed outreach invitations significantly improve HCC surveillance rates in patients with cirrhosis: a randomized clinical trial.
Hepatology 2019 Jan;69(1):121-30. doi: 10.1002/hep.30129..
Keywords: Cancer, Racial and Ethnic Minorities, Prevention, Comparative Effectiveness, Screening
Tyson MD, Alvarez J, Koyama T
Racial variation in patient-reported outcomes following treatment for localized prostate cancer: results from the CEASAR study.
This study tested the hypothesis that treatment-related changes in urinary, bowel, sexual, and hormonal function vary by race/ethnicity. It concluded that the effect of treatment for prostate cancer on patient-reported function did not vary dramatically by race/ethnicity. Compared to white men, African-American men experienced a somewhat more pronounced decline in urinary continence after radical prostatectomy.
AHRQ-funded; HS019356; HS022640.
Citation: Tyson MD, Alvarez J, Koyama T .
Racial variation in patient-reported outcomes following treatment for localized prostate cancer: results from the CEASAR study.
Eur Urol 2017 Aug;72(2):307-14. doi: 10.1016/j.eururo.2016.10.036.
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Keywords: Comparative Effectiveness, Patient-Centered Outcomes Research, Cancer: Prostate Cancer, Racial and Ethnic Minorities, Surgery
Halbert CH, Bellamy S, Briggs V
A comparative effectiveness education trial for lifestyle health behavior change in African Americans.
The authors of this study compared the effects of alternate behavioral interventions on obesity-related health behaviors by conducting a comparative effectiveness education trial in a community-based sample of 530 adult African Americans. The investigators suggest that education about risk factors for chronic disease and evidence-based strategies for health behavior change may be useful for addressing obesity-related behaviors among African Americans.
AHRQ-funded; HS019339.
Citation: Halbert CH, Bellamy S, Briggs V .
A comparative effectiveness education trial for lifestyle health behavior change in African Americans.
Health Educ Res 2017 Jun 1;32(3):207-18. doi: 10.1093/her/cyx039..
Keywords: Comparative Effectiveness, Education: Patient and Caregiver, Lifestyle Changes, Lifestyle Changes, Obesity, Racial and Ethnic Minorities
Bangalore S, Ogedegbe G, Gyamfi J
Outcomes with angiotensin-converting enzyme inhibitors vs other antihypertensive agents in hypertensive blacks.
The study’s objective was to evaluate the effectiveness of angiotensin-converting enzyme inhibitors when compared with other antihypertensive agents in hypertensive blacks. It found that in a large cohort of hypertensive blacks, angiotensin-converting enzyme inhibitors were associated with less benefit when compared with calcium channel blockers or thiazide diuretics.
AHRQ-funded; HS018589.
Citation: Bangalore S, Ogedegbe G, Gyamfi J .
Outcomes with angiotensin-converting enzyme inhibitors vs other antihypertensive agents in hypertensive blacks.
Am J Med 2015 Nov;128(11):1195-203. doi: 10.1016/j.amjmed.2015.04.034..
Keywords: Blood Pressure, Racial and Ethnic Minorities, Medication, Outcomes, Cardiovascular Conditions, Patient-Centered Outcomes Research, Evidence-Based Practice, Comparative Effectiveness
Ogedegbe G, Shah NR, Phillips C
Comparative effectiveness of angiotensin-converting enzyme inhibitor-based treatment on cardiovascular outcomes in hypertensive Blacks versus Whites.
This study evaluated the comparative effectiveness of an ACE inhibitor–based regimen on a composite outcome of all-cause mortality, stroke, and acute myocardial infarction (AMI) in hypertensive blacks compared with whites. ACE inhibitor–based therapy was associated with poorer cardiovascular outcomes in hypertensive blacks but not in whites.
AHRQ-funded; HS018589.
Citation: Ogedegbe G, Shah NR, Phillips C .
Comparative effectiveness of angiotensin-converting enzyme inhibitor-based treatment on cardiovascular outcomes in hypertensive Blacks versus Whites.
J Am Coll Cardiol 2015 Sep 15;66(11):1224-33. doi: 10.1016/j.jacc.2015.07.021..
Keywords: Comparative Effectiveness, Patient-Centered Outcomes Research, Cardiovascular Conditions, Racial and Ethnic Minorities, Medication
Brody H, Croisant SA, Crowder JW
Ethical issues in patient-centered outcomes research and comparative effectiveness research: a pilot study of community dialogue.
Community bioethics dialogues were held on the topic of patient-centered outcomes research (PCOR) and comparative effectiveness research (CER). Participants were 65 and older and represented either a lower income, African American group or a higher income White group. The groups showed both independence in judgment from the investigators and diversity of opinion between the two groups.
AHRQ-funded; HS022134.
Citation: Brody H, Croisant SA, Crowder JW .
Ethical issues in patient-centered outcomes research and comparative effectiveness research: a pilot study of community dialogue.
J Empir Res Hum Res Ethics 2015 Feb;10(1):22-30. doi: 10.1177/1556264614568426..
Keywords: Communication, Comparative Effectiveness, Patient-Centered Outcomes Research, Racial and Ethnic Minorities, Social Determinants of Health
Nurgalieva ZZ, Franzini L, Morgan RO
Utilization of lymph node dissection, race/ethnicity, and breast cancer outcomes.
This study reports on the impact of nodal surgery utilization on survival among white, African American, Hispanic, and Asian women in a large population of women with breast cancer. It found that the disparities in survival among African American and Hispanic women with breast cancer are not explained by nodal surgery utilization among women with micrometastasis and macrometastasis in sentinel lymph nodes.
AHRQ-funded; HS018956.
Citation: Nurgalieva ZZ, Franzini L, Morgan RO .
Utilization of lymph node dissection, race/ethnicity, and breast cancer outcomes.
Am J Manag Care 2013 Oct;19(10):805-10..
Keywords: Cancer: Breast Cancer, Comparative Effectiveness, Disparities, Patient-Centered Outcomes Research, Racial and Ethnic Minorities