Targeted Healthcare Engineering for Systems Interventions in Stroke (THESIS)

Citation:
Liberman AL, Lendaris AR, Cheng NT, et al. Treating High-Risk TIA and Minor Stroke Patients With Dual Antiplatelet Therapy: A National Survey of Emergency Medicine Physicians. Neurohospitalist. 2022;12(1):13-18.

Summary:
Treatment with aspirin plus clopidogrel, dual antiplatelet therapy (DAPT), within 24 hours of high-risk transient ischemic attack (TIA) or minor stroke symptoms to eligible patients is recommended by national guidelines. Whether or not this treatment has been adopted by emergency medicine (EM) physicians is uncertain. This study conducted an online survey of EM physicians in the United States regarding physician characteristics, practice settings, and usual approach to TIA and minor stroke treatment.

Citation:
Saleh Velez FG, Alvarado-Dyer R, Pinto CB, et al. Safer Stroke-Dx Instrument: Identifying Stroke Misdiagnosis in the Emergency Department. Circ Cardiovasc Qual Outcomes. 2021 Jul;14(7):e007758.

Summary:
Missed or delayed diagnosis of acute stroke, or false-negative stroke (FNS), at initial emergency department (ED) presentation occurs in approximately 9% of confirmed stroke patients. Failure to rapidly diagnose stroke can preclude time-sensitive treatments, resulting in higher risks of severe sequelae and disability. The authors of this article developed and tested a modified version of a structured medical record review tool, the Safer Dx Instrument, to identify FNS in a subgroup of hospitalized patients with stroke to gain insight into sources of ED stroke misdiagnosis.

Citation:
Sheibani N, Wong KH, Turan TN, et al. White Matter Hyperintensity and Cardiovascular Disease Outcomes in the SPRINT MIND Trial. J Stroke Cerebrovasc Dis. 2021;30(6):105764.

Summary:
This secondary analysis of the Systolic Blood Pressure Intervention Trial (SPRINT) MIND ancillary study evaluated the association between baseline white matter hyperintensity volume (WMHv) and cardiovascular events during follow-up in the overall sample.

Citation:
Mayampurath A, Parnianpour Z, Richards CT, et al. Improving Prehospital Stroke Diagnosis Using Natural Language Processing of Paramedic Reports. Stroke. 2021 Aug;52(8):2676-2679.

Summary:
Accurate prehospital diagnosis of stroke by emergency medical services (EMS) can increase treatments rates, mitigate disability, and reduce stroke deaths. This study sought to develop a model that utilizes natural language processing of EMS reports and machine learning to improve prehospital stroke identification.