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- Adverse Events (1)
- Blood Pressure (1)
- Chronic Conditions (1)
- Diabetes (2)
- Disparities (1)
- Healthcare Cost and Utilization Project (HCUP) (1)
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- Labor and Delivery (2)
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- Maternal Care (2)
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- Newborns/Infants (4)
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- (-) Pregnancy (10)
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- Social Determinants of Health (1)
- Substance Abuse (1)
- Women (3)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 10 of 10 Research Studies DisplayedPu J, Zhao B, Wang EJ
Racial/ethnic differences in gestational diabetes prevalence and contribution of common risk factors.
This study aimed to assess racial/ethnic differences in relative contribution of risk factors of gestational diabetes mellitus (GDM) among Asian subgroups (Asian Indian, Chinese, Filipino, Japanese, Korean, and Vietnamese), Hispanics, non-Hispanic blacks, and non-Hispanic whites. It found that GDM was most prevalent among Asian Indians (19.3 percent). Relative risks were similar across all race/ethnic groups.
AHRQ-funded; HS019815.
Citation: Pu J, Zhao B, Wang EJ .
Racial/ethnic differences in gestational diabetes prevalence and contribution of common risk factors.
Paediatr Perinat Epidemiol 2015 Sep;29(5):436-43. doi: 10.1111/ppe.12209.
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Keywords: Diabetes, Obesity, Pregnancy, Racial and Ethnic Minorities, Risk, Women
Tang JW, Foster KE, Pumarino J
Perspectives on prevention of type 2 diabetes after gestational diabetes: a qualitative study of Hispanic, African-American and White women.
This qualitative study explored the perspectives of Hispanic, African-American, and White women affected by gestational diabetes mellitus (GDM). The goal is for this work to inform the development of effective approaches to engage diverse populations affected by GDM in taking steps to reduce their risk for type 2 diabetes mellitus.
AHRQ-funded; HS021141.
Citation: Tang JW, Foster KE, Pumarino J .
Perspectives on prevention of type 2 diabetes after gestational diabetes: a qualitative study of Hispanic, African-American and White women.
Matern Child Health J 2015 Jul;19(7):1526-34. doi: 10.1007/s10995-014-1657-y..
Keywords: Diabetes, Lifestyle Changes, Pregnancy, Prevention, Racial and Ethnic Minorities, Risk, Women
Jack B, Bickmore T, Hempstead M
Reducing preconception risks among African American women with conversational agent technology.
The researchers developed and tested “Gabby,” an online preconception conversational agent system, in a 6-month randomized controlled trial of non-pregnant African American women, most in college, to determine how well Gabby works and to identify additional areas for improvement. They found that Gabby was significantly associated with preconception risk reduction.
AHRQ-funded; 290200600012I.
Citation: Jack B, Bickmore T, Hempstead M .
Reducing preconception risks among African American women with conversational agent technology.
J Am Board Fam Med 2015 Jul-Aug;28(4):441-51. doi: 10.3122/jabfm.2015.04.140327..
Keywords: Disparities, Health Promotion, Risk, Pregnancy
Huybrechts KF, Bateman BT, Palmsten K
Antidepressant use late in pregnancy and risk of persistent pulmonary hypertension of the newborn.
This study examined the risk of persistent pulmonary hypertension of the Newborn (PPHN) associated with exposure to different antidepressant medication classes late in pregnancy. Its findings suggest that the risk of PPHN associated with late pregnancy exposure to selective serotonin reuptake inhibitor antidepressants—if present—is smaller than previous studies.
AHRQ-funded; HS018533.
Citation: Huybrechts KF, Bateman BT, Palmsten K .
Antidepressant use late in pregnancy and risk of persistent pulmonary hypertension of the newborn.
JAMA 2015 Jun 2;313(21):2142-51. doi: 10.1001/jama.2015.5605..
Keywords: Medication, Newborns/Infants, Pregnancy, Risk
Cavazos-Rehg PA, Krauss MJ, Spitznagel EL
Maternal age and risk of labor and delivery complications.
The researchers examined associations between maternal age and prevalence of maternal morbidity during complications of labor and delivery. Using HCUP data, they found that complications with the highest odds among women 11-18 years of age included preterm delivery, chorioamnionitis, endometritis, and mild preeclampsia. Pregnant women 15-19 years old had greater odds for severe preeclampsia, eclampsia, postpartum hemorrhage, poor fetal growth, and fetal distress. Pregnant women 35 and older had greater odds for preterm delivery, hypertension, superimposed preeclampsia, severe preeclampsia, and decreased risk for chorioamnionitis. Women over 40 had increased odds for mild preeclampsia, fetal distress, and poor fetal growth.
AHRQ-funded; HS019455.
Citation: Cavazos-Rehg PA, Krauss MJ, Spitznagel EL .
Maternal age and risk of labor and delivery complications.
Matern Child Health J 2015 Jun;19(6):1202-11. doi: 10.1007/s10995-014-1624-7.
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Keywords: Adverse Events, Healthcare Cost and Utilization Project (HCUP), Labor and Delivery, Pregnancy, Risk
Desai RJ, Huybrechts KF, Hernandez-Diaz S
Exposure to prescription opioid analgesics in utero and risk of neonatal abstinence syndrome: population based cohort study.
The study’s objective was to provide risk estimates of neonatal abstinence syndrome (NAS) based on prescription opioid duration and timing of use during pregnancy in the presence or absence of additional risk factors for NAS. It found that the risk of NAS is higher in women using long term prescription opioids when there is a history of drug or alcohol misuse and smoking.
AHRQ-funded; HS018533.
Citation: Desai RJ, Huybrechts KF, Hernandez-Diaz S .
Exposure to prescription opioid analgesics in utero and risk of neonatal abstinence syndrome: population based cohort study.
BMJ 2015 May 14;350:h2102. doi: 10.1136/bmj.h2102..
Keywords: Newborns/Infants, Substance Abuse, Pregnancy, Risk
Bateman BT, Hernandez-Diaz S, Fischer MA
Statins and congenital malformations: cohort study.
The researchers undertook an epidemiologic study to assess the association between statin use in the first trimester and the risk of congenital malformations, using data derived from a large cohort of Medicaid beneficiaries. They found that women taking statins during the first trimester of pregnancy were at an increased risk of delivering an infant with malformations. The association was explained by underlying characteristics of users, mainly pre-existing diabetes.
AHRQ-funded; HS018533.
Citation: Bateman BT, Hernandez-Diaz S, Fischer MA .
Statins and congenital malformations: cohort study.
BMJ 2015 Mar 17;350:h1035. doi: 10.1136/bmj.h1035..
Keywords: Pregnancy, Medication, Risk, Newborns/Infants
Bateman BT, Huybrechts KF, Fischer MA
Chronic hypertension in pregnancy and the risk of congenital malformations: a cohort study.
The researchers sought to examine the effect of chronic hypertension on the risk of congenital malformations in a large cohort of pregnancies in Medicaid beneficiaries. In a cohort of 878,126 pregnancies, they found that both treated and untreated maternal chronic hypertension were associated with a similar 20-30 percent increase in the risk of congenital malformations in the infant after adjusting for confounding factors as compared with normotensive controls.
AHRQ-funded; HS018533.
Citation: Bateman BT, Huybrechts KF, Fischer MA .
Chronic hypertension in pregnancy and the risk of congenital malformations: a cohort study.
Am J Obstet Gynecol 2015 Mar;212(3):337.e1-14. doi: 10.1016/j.ajog.2014.09.031..
Keywords: Blood Pressure, Chronic Conditions, Pregnancy, Risk, Maternal Care, Women
Witt WP, Wisk LE, Cheng ER
Determinants of cesarean delivery in the US: a lifecourse approach.
The researchers sought to determine whether the effects of preconception stressful life events (PSLEs) on birth weight differed by neighborhood disadvantage. They found that the risk of having very low birthweight infants among women with PSLEs, women with chronic conditions, or minority women was strongest among those living in disadvantaged neighborhoods, which suggests exacerbation of risk within disadvantaged environments.
AHRQ-funded; HS000083; HS000063.
Citation: Witt WP, Wisk LE, Cheng ER .
Determinants of cesarean delivery in the US: a lifecourse approach.
Matern Child Health J 2015 Jan;19(1):84-93. doi: 10.1007/s10995-014-1498-8..
Keywords: Labor and Delivery, Maternal Care, Pregnancy, Risk, Social Determinants of Health
Fleisch AF, Rifas-Shiman SL, Koutrakis P
Prenatal exposure to traffic pollution: associations with reduced fetal growth and rapid infant weight gain.
The authors explored air pollution exposure implications for postnatal growth. They found that infants exposed to the highest quartile of neighborhood traffic density had lower fetal growth, more rapid 0- to 6-month weight-for-length gain, and higher odds of weight-for-length ≥95th percentile at 6 months. Neighborhood traffic density was additionally associated with an infant being in both the lowest quartile of fetal growth and the highest quartile of 0- to 6-month weight-for-length gain.
AHRQ-funded; HS000063.
Citation: Fleisch AF, Rifas-Shiman SL, Koutrakis P .
Prenatal exposure to traffic pollution: associations with reduced fetal growth and rapid infant weight gain.
Epidemiology 2015 Jan;26(1):43-50. doi: 10.1097/ede.0000000000000203.
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Keywords: Newborns/Infants, Newborns/Infants, Obesity, Pregnancy, Risk