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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedChase BA, Pocica S, Frigerio R
Mortality risk factors in newly diagnosed diabetic cardiac autonomic neuropathy.
To inform the design of interventions to reduce mortality in cardiac autonomic neuropathy (CAN) patients with diabetes, researchers explored genetic variants,
clinical attributes, and autonomic testing findings present to assess possible associations with increased mortality. They reviewed the electronic medical records of patients with advanced disease at the time when CAN was diagnosed. Some clinical characteristics, as well as sex, race, ethnicity, and incidence of type 1 or type 2 diabetes mellitus were found to be similar in both survivors and non-survivors; clinical and autonomic testing characteristics were often similarly advanced in survivors and non-survivors. The researchers concluded that their analysis provided context by estimating hazard ratios relative to when CAN is objectively diagnosed and indicated that not all risk factors confer equal mortality risk. Their findings may inform both the development of guidelines for prevention and the design of larger studies to evaluate CAN mortality risk factors.
clinical attributes, and autonomic testing findings present to assess possible associations with increased mortality. They reviewed the electronic medical records of patients with advanced disease at the time when CAN was diagnosed. Some clinical characteristics, as well as sex, race, ethnicity, and incidence of type 1 or type 2 diabetes mellitus were found to be similar in both survivors and non-survivors; clinical and autonomic testing characteristics were often similarly advanced in survivors and non-survivors. The researchers concluded that their analysis provided context by estimating hazard ratios relative to when CAN is objectively diagnosed and indicated that not all risk factors confer equal mortality risk. Their findings may inform both the development of guidelines for prevention and the design of larger studies to evaluate CAN mortality risk factors.
AHRQ-funded; HS024057.
Citation: Chase BA, Pocica S, Frigerio R .
Mortality risk factors in newly diagnosed diabetic cardiac autonomic neuropathy.
Clin Auton Res 2023 Dec; 33(6):903-07. doi: 10.1007/s10286-023-00975-5.
Keywords: Mortality, Risk, Diabetes