National Healthcare Quality and Disparities Report
Latest available findings on quality of and access to health care
Data
- Data Infographics
- Data Visualizations
- Data Tools
- Data Innovations
- All-Payer Claims Database
- Healthcare Cost and Utilization Project (HCUP)
- Medical Expenditure Panel Survey (MEPS)
- AHRQ Quality Indicator Tools for Data Analytics
- State Snapshots
- United States Health Information Knowledgebase (USHIK)
- Data Sources Available from AHRQ
Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Drug Events (ADE) (3)
- Adverse Events (5)
- Alcohol Use (1)
- Antibiotics (1)
- Arthritis (9)
- Asthma (4)
- Behavioral Health (11)
- Blood Clots (1)
- Blood Thinners (1)
- Brain Injury (1)
- Cancer (10)
- Cancer: Breast Cancer (1)
- Cancer: Colorectal Cancer (1)
- Cancer: Prostate Cancer (2)
- Cardiovascular Conditions (9)
- Care Management (2)
- Case Study (1)
- Children/Adolescents (7)
- Chronic Conditions (9)
- Clinician-Patient Communication (1)
- Community-Acquired Infections (1)
- Community-Based Practice (1)
- (-) Comparative Effectiveness (128)
- Complementary and Alternative Medicine (3)
- Critical Care (2)
- Data (6)
- Depression (3)
- Diabetes (4)
- Diagnostic Safety and Quality (3)
- Digestive Disease and Health (2)
- Education: Continuing Medical Education (2)
- Elderly (9)
- Electronic Health Records (EHRs) (1)
- Evidence-Based Practice (21)
- Guidelines (3)
- Healthcare-Associated Infections (HAIs) (2)
- Healthcare Cost and Utilization Project (HCUP) (1)
- Healthcare Costs (3)
- Healthcare Delivery (1)
- Health Information Technology (HIT) (6)
- Health Insurance (1)
- Health Literacy (1)
- Health Status (1)
- Heart Disease and Health (10)
- Hospitalization (2)
- Hospital Readmissions (3)
- Human Immunodeficiency Virus (HIV) (1)
- Imaging (4)
- Infectious Diseases (1)
- Injuries and Wounds (1)
- Intensive Care Unit (ICU) (3)
- Kidney Disease and Health (8)
- Lifestyle Changes (2)
- Medical Devices (7)
- Medicare (5)
- Medication (35)
- Medication: Safety (2)
- Methicillin-Resistant Staphylococcus aureus (MRSA) (1)
- Mortality (5)
- Newborns/Infants (2)
- Nursing Homes (1)
- Obesity (1)
- Opioids (1)
- Outcomes (26)
- Pain (4)
- Palliative Care (1)
- Patient-Centered Outcomes Research (42)
- Patient Adherence/Compliance (4)
- Patient and Family Engagement (1)
- Patient Experience (1)
- Patient Safety (1)
- Pneumonia (1)
- Policy (1)
- Practice-Based Research Network (PBRN) (1)
- Pregnancy (1)
- Prevention (5)
- Primary Care (1)
- Primary Care: Models of Care (1)
- Provider (1)
- Provider: Health Personnel (2)
- Provider: Pharmacist (1)
- Quality Improvement (2)
- Quality of Care (3)
- Quality of Life (4)
- Registries (4)
- Rehabilitation (1)
- Research Methodologies (17)
- Respiratory Conditions (2)
- Risk (8)
- Sepsis (1)
- Shared Decision Making (3)
- Sleep Problems (1)
- Stroke (2)
- Substance Abuse (2)
- Surgery (12)
- Teams (1)
- Telehealth (4)
- Transitions of Care (1)
- Transplantation (1)
- Treatments (10)
- Vaccination (1)
- Web-Based (1)
- Women (2)
AHRQ Research Studies
Sign up: AHRQ Research Studies Email updates
Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
76 to 100 of 128 Research Studies DisplayedSpangler EL, Goodney PP, Schanzer A
Outcomes of carotid endarterectomy versus stenting in comparable medical risk patients.
The purpose of this study was to compare risk-stratified outcomes of carotid artery stenting (CAS) and carotid endarterectomy (CEA). Included in the study group were 11,336 patients who underwent isolated primary CEA and 544 who underwent primary CAS. The researchers found that asymptomatic normal- and high-risk patients do equally well after CEA or CAS. However, normal- and high-risk symptomatic patients have substantially worse outcomes with CAS compared with CEA.
AHRQ-funded; HS021581.
Citation: Spangler EL, Goodney PP, Schanzer A .
Outcomes of carotid endarterectomy versus stenting in comparable medical risk patients.
J Vasc Surg 2014 Nov;60(5):1227-31, 31.e1. doi: 10.1016/j.jvs.2014.05.044..
Keywords: Outcomes, Comparative Effectiveness, Risk, Cardiovascular Conditions, Heart Disease and Health
Blanco C, Okuda M, Wang S
Testing the drug substitution switching-addictions hypothesis. A prospective study in a nationally representative sample.
The researchers tested whether remission from a substance use disorder (SUD) would increase the probability of new onset of an SUD. In a national sample of 34,653 adults, they found that contrary to a common clinical perception, remission from an SUD decreases rather than increases the risk of onset of another SUD.
AHRQ-funded; HS021112
Citation: Blanco C, Okuda M, Wang S .
Testing the drug substitution switching-addictions hypothesis. A prospective study in a nationally representative sample.
JAMA Psychiatry. 2014 Nov;71(11):1246-53. doi: 10.1001/jamapsychiatry.2014.1206..
Keywords: Comparative Effectiveness, Substance Abuse, Behavioral Health
Curtis JR, Zhang J, Xie F
Use of oral and subcutaneous methotrexate in rheumatoid arthritis patients in the United States.
The researchers aimed to examine the epidemiology of methotrexate (MTX) use among rheumatoid arthritis patients initiating MTX, including dosing, method of administration (oral versus subcutaneous (SC)) , and persistence. They also compare the effectiveness of 2 strategies in regard to delaying or avoiding use of biologic agents: switching to SC MTX or adding another nonbiologic disease-modifying antirheumatic drug.
AHRQ-funded; HS018517
Citation: Curtis JR, Zhang J, Xie F .
Use of oral and subcutaneous methotrexate in rheumatoid arthritis patients in the United States.
Arthritis Care Res. 2014 Nov;66(11):1604-11. doi: 10.1002/acr.22383..
Keywords: Arthritis, Comparative Effectiveness, Medication
Goode AP, Shi XA, Gracely RH
Associations between pressure-pain threshold, symptoms, and radiographic knee and hip osteoarthritis.
The researchers sought to determine the association between generalized evoked pressure pain sensitivity with distal pressure–pain threshold and the presence, severity, or number of involved knee/hip joints with radiographic osteoarthritis or related symptoms. They found that as a participant’s sensitivity for pressure pain decreased, there were several significant associations with presence, severity, and number of joints with symptoms, regardless of the knee or hip joint.
AHRQ-funded; HS019479
Citation: Goode AP, Shi XA, Gracely RH .
Associations between pressure-pain threshold, symptoms, and radiographic knee and hip osteoarthritis.
Arthritis Care Res. 2014 Oct;66(10):1513-9. doi: 10.1002/acr.22321.
Keywords: Arthritis, Pain, Comparative Effectiveness
Ramnath VR, Khazeni N
Centralized monitoring and virtual consultant models of tele-ICU care: a side-by-side review.
This side-by-side review directly compares the Centralized Monitoring and Virtual Consultant tele-ICU Models. The Centralized Monitoring tele-ICU Model showed improved mortality and/or length of stay and staff acceptance, particularly in rural or specific patient populations, but with high costs and unclear savings. The Virtual Consultant Model could not be adequately evaluated for effects on clinical outcomes or staff acceptance given minimal data; however, it can be both portable and implemented at a lower cost profile. Improved compliance with clinical practice guidelines was seen in both models. Further study is recommended.
AHRQ-funded; HS019816.
Citation: Ramnath VR, Khazeni N .
Centralized monitoring and virtual consultant models of tele-ICU care: a side-by-side review.
Telemed J E Health 2014 Oct;20(10):962-71. doi: 10.1089/tmj.2014.0024.
.
.
Keywords: Critical Care, Comparative Effectiveness, Quality of Care, Intensive Care Unit (ICU), Telehealth
Ramnath VR, Ho L, Maggio LA
Centralized monitoring and virtual consultant models of tele-ICU care: a systematic review.
This systematic literature review compares the Centralized Monitoring and Virtual Consultant tele-ICU Models. Compared with the Virtual Consultant tele-ICU Model, studies addressing the Centralized Monitoring Model of tele-ICU care were greater in quantity and sample size, with qualitative conclusions of clinical outcomes, staff satisfaction and workload, and financial sustainability largely consistent with past systematic reviews.
AHRQ-funded; HS019816.
Citation: Ramnath VR, Ho L, Maggio LA .
Centralized monitoring and virtual consultant models of tele-ICU care: a systematic review.
Telemed J E Health 2014 Oct;20(10):936-61. doi: 10.1089/tmj.2013.0352.
.
.
Keywords: Critical Care, Comparative Effectiveness, Quality of Care, Intensive Care Unit (ICU), Telehealth
Lairson DR, Parikh RC, Cormier JN
Cost-utility analysis of chemotherapy regimens in elderly patients with stage III colon cancer.
The authors investigated community-level evidence on the effectiveness and cost effectiveness of treatment for stage III colon cancer for elderly patients among those receiving no chemotherapy, 5-fluorouracil (5-FU), and FOLFOX (5-FU + oxaliplatin). They concluded that FOLFOX appears more effective and cost effective than other strategies for colon cancer treatment of older patients, with results being sensitive to age.
AHRQ-funded; HS018956.
Citation: Lairson DR, Parikh RC, Cormier JN .
Cost-utility analysis of chemotherapy regimens in elderly patients with stage III colon cancer.
Pharmacoeconomics 2014 Oct;32(10):1005-13. doi: 10.1007/s40273-014-0180-8.
.
.
Keywords: Cancer: Colorectal Cancer, Comparative Effectiveness, Healthcare Costs, Elderly, Patient-Centered Outcomes Research
Septimus EJ, Hayden MK, Kleinman K
Does chlorhexidine bathing in adult intensive care units reduce blood culture contamination? A pragmatic cluster-randomized trial.
The investigators determined rates of blood culture contamination comparing 3 strategies to prevent intensive care unit (ICU) infections: screening and isolation, targeted decolonization, and universal decolonization. They demonstrated that universal decolonization with mupirocin and chlorhexidine bathing resulted in a significant reduction in blood culture contamination.
AHRQ-funded; 290201000008I; 290032007T.
Citation: Septimus EJ, Hayden MK, Kleinman K .
Does chlorhexidine bathing in adult intensive care units reduce blood culture contamination? A pragmatic cluster-randomized trial.
Infect Control Hosp Epidemiol 2014 Oct;35 Suppl 3:S17-22. doi: 10.1086/677822.
.
.
Keywords: Comparative Effectiveness, Healthcare-Associated Infections (HAIs), Intensive Care Unit (ICU), Methicillin-Resistant Staphylococcus aureus (MRSA), Sepsis
Cook EA, Schneider KM, Robinson J
Field methods in medical record abstraction: assessing the properties of comparative effectiveness estimates.
Comparative effectiveness studies using Medicare claims data are vulnerable to treatment selection biases and supplemental data from a sample of patients has been recommended for examining the magnitude of this bias. The investigators collected medical record data from a subsample of patients to assess the validity of assumptions and to aid in the interpretation of our estimates. In this paper, they sought to describe and document the process used to collect and validate this supplemental information.
AHRQ-funded; HS018381.
Citation: Cook EA, Schneider KM, Robinson J .
Field methods in medical record abstraction: assessing the properties of comparative effectiveness estimates.
BMC Health Serv Res 2014 Sep 15;14:391. doi: 10.1186/1472-6963-14-391..
Keywords: Comparative Effectiveness, Medicare, Evidence-Based Practice, Research Methodologies
Parmar AD, Coutin MD, Vargas GM
Cost-effectiveness of elective laparoscopic cholecystectomy versus observation in older patients presenting with mild biliary disease.
The objective was to determine the threshold for probability of recurrent symptoms at which elective cholecystectomy became the most effective and cost-effective options for older patients with mild biliary disease. This procedure was more effective than observation when the probability of continued symptoms exceeded 45.3 percent; when the probability exceeded 82.7 percent, the procedure became more cost-effective as well.
AHRQ-funded; HS022134
Citation: Parmar AD, Coutin MD, Vargas GM .
Cost-effectiveness of elective laparoscopic cholecystectomy versus observation in older patients presenting with mild biliary disease.
J Gastrointest Surg. 2014 Sep;18(9):1616-22. doi: 10.1007/s11605-014-2570-9..
Keywords: Comparative Effectiveness, Healthcare Costs, Elderly, Surgery
Dood RL, Gracia CR, Sammel MD
Endometrial cancer after endometrial ablation vs medical management of abnormal uterine bleeding.
The authors investigated whether endometrial ablation is associated with increased risk or delayed diagnosis of endometrial cancer compared with medical management of abnormal uterine bleeding. They observed no difference in endometrial cancer rates, nor was there a delay in diagnosis when comparing endometrial ablation vs medical management.
AHRQ-funded; HS021336.
Citation: Dood RL, Gracia CR, Sammel MD .
Endometrial cancer after endometrial ablation vs medical management of abnormal uterine bleeding.
J Minim Invasive Gynecol 2014 Sep-Oct;21(5):744-52. doi: 10.1016/j.jmig.2014.02.012.
.
.
Keywords: Cancer, Comparative Effectiveness, Diagnostic Safety and Quality, Patient-Centered Outcomes Research, Women
Tang DH, Warholak TL, Hines LE
Evaluation of Pharmacy and Therapeutic (P&T) Committee member knowledge, attitudes and ability regarding the use of comparative effectiveness research (CER) in health care decision-making.
This study was conducted to evaluate changes in CER knowledge, attitudes, and ability among Pharmacy and Therapeutics (P&T) Committee members and support staff after attending a tailored educational program. It found that the CER educational program was effective in increasing participants’ CER knowledge and self-perceived ability to evaluate relevant evidence.
AHRQ-funded; HS019220.
Citation: Tang DH, Warholak TL, Hines LE .
Evaluation of Pharmacy and Therapeutic (P&T) Committee member knowledge, attitudes and ability regarding the use of comparative effectiveness research (CER) in health care decision-making.
Res Social Adm Pharm 2014 Sep-Oct;10(5):768-80. doi: 10.1016/j.sapharm.2013.11.008..
Keywords: Comparative Effectiveness, Shared Decision Making, Evidence-Based Practice
Vargas GM, Parmar AD, Sheffield KM
Impact of liver-directed therapy in colorectal cancer liver metastases.
This study evaluated the use of liver resection, ablation, and chemoembolization (LDT) in older patients presenting with metastatic colorectal cancer in the setting of improved chemotherapy. It found that many older patients deemed to be appropriate candidates for resection of the primary tumor and receipt of systemic chemotherapy did not receive LDT.
AHRQ-funded; HS022134
Citation: Vargas GM, Parmar AD, Sheffield KM .
Impact of liver-directed therapy in colorectal cancer liver metastases.
J Surg Res. 2014 Sep;191(1):42-50. doi: 10.1016/j.jss.2014.05.070..
Keywords: Comparative Effectiveness, Patient-Centered Outcomes Research, Elderly, Surgery
Schelleman H, Han X, Brensinger CM
Pharmacoepidemiologic and in vitro evaluation of potential drug-drug interactions of sulfonylureas with fibrates and statins.
This study examined whether initiation of fibrates or statins in sulfonylurea users is associated with hypoglycemia and in vitro inhibition of cytochrome P450 (CYP) enzymes by statins, fenofibrate and glipizide. It found that use of fenofibrate or gemfibrozil together with glyburide was associated with
elevated overall risks of serious hypoglycemia.
elevated overall risks of serious hypoglycemia.
AHRQ-funded; HS019818.
Citation: Schelleman H, Han X, Brensinger CM .
Pharmacoepidemiologic and in vitro evaluation of potential drug-drug interactions of sulfonylureas with fibrates and statins.
Br J Clin Pharmacol 2014 Sep;78(3):639-48. doi: 10.1111/bcp.12353..
Keywords: Comparative Effectiveness, Medication, Risk
Wu AC, Li L, Fung V
Use of leukotriene receptor antagonists are associated with a similar risk of asthma exacerbations as inhaled corticosteroids.
The researchers compared the effectiveness of different controller medication regimens under real-life conditions. They found that the risk of emergency department visits, hospitalizations, and oral corticosteroids did not differ between children who initiated leukotriene antagonist and those who initiated inhaled corticosteroid. These findings may be explainable by leukotriene antagonist having similar effectiveness as inhaled corticosteroid in real-life usage.
AHRQ-funded; HS019669.
Citation: Wu AC, Li L, Fung V .
Use of leukotriene receptor antagonists are associated with a similar risk of asthma exacerbations as inhaled corticosteroids.
J Allergy Clin Immunol Pract 2014 Sep-Oct;2(5):607-13. doi: 10.1016/j.jaip.2014.05.009..
Keywords: Comparative Effectiveness, Medication, Children/Adolescents, Asthma, Risk
Feudtner C, Freedman J, Kang T
Comparative effectiveness of senna to prevent problematic constipation in pediatric oncology patients receiving opioids: a multicenter study of clinically detailed administrative data.
The researcher investigated senna’s effectiveness, compared with other prophylactic oral bowel medications, in reducing opioid-induced constipation in pediatric cancer patients. They found that initiating senna therapy within two days of starting opioids, compared with initiating another oral bowel medication, was significantly associated with a lower risk of problematic constipation.
AHRQ-funded; HS018425.
Citation: Feudtner C, Freedman J, Kang T .
Comparative effectiveness of senna to prevent problematic constipation in pediatric oncology patients receiving opioids: a multicenter study of clinically detailed administrative data.
J Pain Symptom Manage 2014 Aug;48(2):272-80. doi: 10.1016/j.jpainsymman.2013.09.009..
Keywords: Cancer, Children/Adolescents, Comparative Effectiveness, Patient-Centered Outcomes Research, Medication
Hartung DM, McCarty D, Fu R
Extended-release naltrexone for alcohol and opioid dependence: a meta-analysis of healthcare utilization studies.
The authors evaluated cost and utilization outcomes between extended-release naltrexone (XR-NTX) and other pharmacotherapies for treatment of alcohol and opioid dependence. They found that alcohol dependent XR-NTX patients had longer medication refill persistence versus acamprosate and oral naltrexone, with healthcare utilization and costs being generally lower or as low for XR-NTX-treated patients relative to other alcohol dependence agents. Opioid dependent XR-NTX patients had lower inpatient substance abuse-related utilization versus other agents and $8170 lower total cost versus methadone.
AHRQ-funded; HS019456.
Citation: Hartung DM, McCarty D, Fu R .
Extended-release naltrexone for alcohol and opioid dependence: a meta-analysis of healthcare utilization studies.
J Subst Abuse Treat 2014 Aug;47(2):113-21. doi: 10.1016/j.jsat.2014.03.007.
.
.
Keywords: Alcohol Use, Comparative Effectiveness, Medication, Opioids, Substance Abuse
Huybrechts KF, Gerhard T, Franklin JM
Instrumental variable applications using nursing home prescribing preferences in comparative effectiveness research.
The objective of this study was to explore the presence of unexplained between-nursing home (NH) variation in prescribing and to empirically evaluate the validity of instruments based on NH prescribing preference. High-prescribing and low-prescribing nursing homes differed by a factor of 2. There was no evidence that instrument status was associated with markers of nursing home quality of care.
AHRQ-funded; 290200500161; HS021112
Citation: Huybrechts KF, Gerhard T, Franklin JM .
Instrumental variable applications using nursing home prescribing preferences in comparative effectiveness research.
Pharmacoepidemiol Drug Saf 2014 Aug;23(8):830-8. doi: 10.1002/pds.3611..
Keywords: Nursing Homes, Comparative Effectiveness, Medication, Quality of Care
Smith SR
AHRQ Author: Smith SR
Preface to the AHRQ supplement.
AHRQ, through its Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Research Network, sponsored this supplement to present various strategies in the design, analysis, and conduct of health outcomes studies relevant to rare diseases. The purpose of this supplement is to disseminate illustrative examples of research methods that can be applied to understand health outcomes and potentially to stimulate new patient-centered outcomes studies for rare diseases.
AHRQ-authored.
Citation: Smith SR .
Preface to the AHRQ supplement.
J Gen Intern Med 2014 Aug;29 Suppl 3:S712-3. doi: 10.1007/s11606-014-2922-x.
.
.
Keywords: Comparative Effectiveness, Evidence-Based Practice, Outcomes, Patient-Centered Outcomes Research, Research Methodologies
Garabedian LF, Chu P, Toh S
Potential bias of instrumental variable analyses for observational comparative effectiveness research.
Results of instrumental variable analyses may be biased if the instrument and outcome are related through an unadjusted third variable, an instrument-outcome confounder. The authors review of 187 comparative effectiveness studies using this type of analysis, only 4 considered potential instrument-outcome confounders outside the study data.
AHRQ-funded; 290050016I
Citation: Garabedian LF, Chu P, Toh S .
Potential bias of instrumental variable analyses for observational comparative effectiveness research.
Ann Intern Med. 2014 Jul 15;161(2):131-8. doi: 10.7326/M13-1887..
Keywords: Comparative Effectiveness, Outcomes, Research Methodologies
Friedly JL, Comstock BA, Turner JA
A randomized trial of epidural glucocorticoid injections for spinal stenosis.
The researchers designed the Lumbar Epidural Steroid Injections for Spinal Stenosis trial to compare the effectiveness of epidural injections of glucocorticoids plus anesthetic with injections of anesthetic alone in patients with lumbar spinal stenosis. They found that epidural injection of glucocorticoids plus lidocaine offered minimal or no short-term benefit as compared with lidocaine alone.
AHRQ-funded; HS019222
Citation: Friedly JL, Comstock BA, Turner JA .
A randomized trial of epidural glucocorticoid injections for spinal stenosis.
N Engl J Med. 2014 Jul 3;371(1):11-21. doi: 10.1056/NEJMoa1313265..
Keywords: Comparative Effectiveness, Chronic Conditions, Elderly, Outcomes
Holmes JH, Elliott TE, Brown JS
Clinical research data warehouse governance for distributed research networks in the USA: a systematic review of the literature.
The researchers reviewed the published, peer-reviewed literature on clinical research data warehouse governance in distributed research networks (DRNs). They determined that a peer-reviewed literature on data warehouse governance is emerging but is still sparse. Understanding of DRN data governance policies and procedures is limited but expected to change as more DRN projects disseminate their governance approaches.
AHRQ-funded; HS019912
Citation: Holmes JH, Elliott TE, Brown JS .
Clinical research data warehouse governance for distributed research networks in the USA: a systematic review of the literature.
J Am Med Inform Assoc. 2014 Jul-Aug;21(4):730-6. doi: 10.1136/amiajnl-2013-002370..
Keywords: Comparative Effectiveness, Data, Health Information Technology (HIT)
McGlynn EA, Lieu TA, Durham ML
Developing a data infrastructure for a learning health system: the PORTAL network.
The authors describe the Patient Outcomes Research To Advance Learning (PORTAL) network established by Kaiser Permanente and three other healthcare delivery systems. They discuss how PORTAL is enhancing its current capabilities by expanding the scope of the common data model and integrating the PCORnet PopMedNet platform across their research centers with the objective of conducting large-scale observational comparative effectiveness research across diverse clinical care settings.
AHRQ-funded; HS022143; HS019912
Citation: McGlynn EA, Lieu TA, Durham ML .
Developing a data infrastructure for a learning health system: the PORTAL network.
J Am Med Inform Assoc. 2014 Jul-Aug;21(4):596-601. doi: 10.1136/amiajnl-2014-002746..
Keywords: Comparative Effectiveness, Patient-Centered Outcomes Research, Health Information Technology (HIT)
Ohno-Machado L, Agha Z, Bell DS
pSCANNER: patient-centered Scalable National Network for Effectiveness Research.
The authors describe the patient-centered Scalable National Network for Effectiveness Research (pSCANNER), which is part of the recently formed Patient-Centered Outcomes Research net (PCORnet). It is designed to be a stakeholder-governed federated network that uses a distributed architecture to integrate data from 3 existing networks covering over 21 million patients in all 50 States.
AHRQ-funded; HS019913
Citation: Ohno-Machado L, Agha Z, Bell DS .
pSCANNER: patient-centered Scalable National Network for Effectiveness Research.
J Am Med Inform Assoc. 2014 Jul-Aug;21(4):621-6. doi: 10.1136/amiajnl-2014-002751..
Keywords: Comparative Effectiveness, Patient-Centered Outcomes Research, Health Information Technology (HIT)
Kumamaru H, Judd SE, Curtis JR
Validity of claims-based stroke algorithms in contemporary Medicare data: reasons for geographic and racial differences in stroke (REGARDS) study linked with medicare claims.
The researchers assessed the validity of diagnostic coding algorithms for identifying stroke in the Medicare population by linking data from the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study to Medicare claims. They found that claims-based algorithms to identify stroke in a contemporary Medicare cohort had high positive predictive value and specificity, supporting their use as outcomes for etiologic and comparative effectiveness studies in similar populations.
AHRQ-funded; HS017731; HS018517.
Citation: Kumamaru H, Judd SE, Curtis JR .
Validity of claims-based stroke algorithms in contemporary Medicare data: reasons for geographic and racial differences in stroke (REGARDS) study linked with medicare claims.
Circ Cardiovasc Qual Outcomes 2014 Jul;7(4):611-9. doi: 10.1161/circoutcomes.113.000743..
Keywords: Stroke, Medicare, Comparative Effectiveness, Outcomes