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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 5 of 5 Research Studies DisplayedMullins BT, Basak R, Broughman JR
Patient-reported sexual quality of life after different types of radical prostatectomy and radiotherapy: analysis of a population-based prospective cohort.
This study compares the effects of different types of radical prostatectomy and radiotherapy on sexual function. A population-based cohort of 835 men with newly diagnosed prostate cancer from 2011 through 2013 was recruited in collaboration with the Rapid Case Ascertainment system of the North Carolina Central Cancer Registry. They were enrolled prior to treatment and followed retrospectively using the validated Prostate Cancer Symptom Indices (PCSI) instrument. The sexual function scores were compared among patients who received the following treatment types: external-beam RT (EBRT), EBRT with androgen deprivation therapy (ADT), brachytherapy, nerve-sparing radical prostatectomy (RP), and non-nerve-sparing RP. The cohort was surveyed at 24 months post-therapy, and RT alone was found to result in the best preservation of sexual function with brachytherapy, RT with ADT, and nerve-sparing RP yielding similar outcomes. Patients treated with non-nerve-sparing RP experienced the worst sexual function outcome.
AHRQ-funded.
Citation: Mullins BT, Basak R, Broughman JR .
Patient-reported sexual quality of life after different types of radical prostatectomy and radiotherapy: analysis of a population-based prospective cohort.
Cancer 2019 Oct 15;125(20):3657-65. doi: 10.1002/cncr.32288..
Keywords: Quality of Life, Sexual Health, Surgery, Treatments, Comparative Effectiveness, Patient-Centered Outcomes Research, Outcomes, Cancer: Prostate Cancer, Cancer, Evidence-Based Practice
Thomas HN, Hamm M, Hess R
Patient-centered outcomes and treatment preferences regarding sexual problems: a qualitative study among midlife women.
This study sought a better understanding of the sexual function outcomes that were most important to sexually active women 45 to 60 years old and the types of treatments they would prefer from individual interviews and focus groups. It found that many midlife women in the sample expressed a preference for behavioral approaches over pharmaceutical approaches for the treatment of sexual dysfunction.
AHRQ-funded; HS022989.
Citation: Thomas HN, Hamm M, Hess R .
Patient-centered outcomes and treatment preferences regarding sexual problems: a qualitative study among midlife women.
J Sex Med 2017 Aug;14(8):1011-17. doi: 10.1016/j.jsxm.2017.05.014..
Keywords: Sexual Health, Women, Patient-Centered Outcomes Research, Quality of Life
Foy CG, Newman JC, Berlowitz DR
Blood pressure, sexual activity, and dysfunction in women with hypertension: baseline findings from the Systolic Blood Pressure Intervention Trial (SPRINT).
The authors assessed the association between systolic blood pressure and other variables, and sexual activity and sexual dysfunction in women with hypertension. They found that younger age, higher education, living with others, and higher weekly alcohol consumption were significantly associated with higher odds of being sexually active in the sample group. They concluded that systolic blood pressure was not significantly associated with sexual activity or sexual dysfunction.
AHRQ-funded; HS022989.
Citation: Foy CG, Newman JC, Berlowitz DR .
Blood pressure, sexual activity, and dysfunction in women with hypertension: baseline findings from the Systolic Blood Pressure Intervention Trial (SPRINT).
J Sex Med 2016 Sep;13(9):1333-46. doi: 10.1016/j.jsxm.2016.06.014.
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Keywords: Blood Pressure, Sexual Health, Women, Quality of Life
Rhoten BA
Head and neck cancer and sexuality: a review of the literature.
The author analyzed nine publications to present a review of the literature on head and neck cancer and sexuality, concluding that existing studies indicate that sexuality is of considerable significance, particularly after treatment for head and neck cancer. She recommended that oncology nurses be aware that this topic is of importance to many patients, and that they should familiarize themselves with available resources.
AHRQ-funded; HS022990.
Citation: Rhoten BA .
Head and neck cancer and sexuality: a review of the literature.
Cancer Nurs 2016 Jul-Aug;39(4):313-20. doi: 10.1097/ncc.0000000000000289.
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Keywords: Cancer, Sexual Health, Quality of Life
Thomas HN, Hess R, Thurston RC
Correlates of sexual activity and satisfaction in midlife and older women.
The authors gave updated prevalence estimates of sexual activity among women and elucidated factors associated with sexual activity and sexual satisfaction. Using the National Survey of Midlife Development in the United States, they found that a considerable proportion of midlife and older women remain sexually active if they have a partner available. Additionally, psychosocial factors matter more to sexual satisfaction than aging among midlife and older women.
AHRQ-funded; HS022989.
Citation: Thomas HN, Hess R, Thurston RC .
Correlates of sexual activity and satisfaction in midlife and older women.
Ann Fam Med 2015 Jul-Aug;13(4):336-42. doi: 10.1370/afm.1820.
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Keywords: Elderly, Women, Sexual Health, Quality of Life