National Healthcare Quality and Disparities Report
Latest available findings on quality of and access to health care
Data
- Data Infographics
- Data Visualizations
- Data Tools
- Data Innovations
- All-Payer Claims Database
- Healthcare Cost and Utilization Project (HCUP)
- Medical Expenditure Panel Survey (MEPS)
- AHRQ Quality Indicator Tools for Data Analytics
- State Snapshots
- United States Health Information Knowledgebase (USHIK)
- Data Sources Available from AHRQ
Search All Research Studies
AHRQ Research Studies Date
Topics
- Access to Care (2)
- Adverse Drug Events (ADE) (2)
- Adverse Events (3)
- Ambulatory Care and Surgery (1)
- Antibiotics (10)
- Antimicrobial Stewardship (1)
- Arthritis (2)
- Behavioral Health (7)
- Blood Clots (1)
- Cancer (7)
- Cancer: Breast Cancer (1)
- Cancer: Skin Cancer (5)
- Cardiovascular Conditions (2)
- Caregiving (1)
- Care Management (2)
- Children/Adolescents (31)
- Chronic Conditions (12)
- Clinician-Patient Communication (1)
- Community-Acquired Infections (2)
- Comparative Effectiveness (1)
- COVID-19 (1)
- Data (1)
- Depression (1)
- Diagnostic Safety and Quality (12)
- Digestive Disease and Health (1)
- Education: Patient and Caregiver (1)
- Elderly (3)
- Emergency Department (3)
- Evidence-Based Practice (12)
- Guidelines (3)
- Healthcare-Associated Infections (HAIs) (2)
- Healthcare Cost and Utilization Project (HCUP) (16)
- Healthcare Costs (12)
- Healthcare Utilization (1)
- Health Insurance (1)
- Health Services Research (HSR) (2)
- Health Status (1)
- Hospital Discharge (1)
- Hospitalization (11)
- Imaging (2)
- Infectious Diseases (3)
- Injuries and Wounds (2)
- Lifestyle Changes (2)
- Long-Term Care (1)
- Medicare (1)
- Medication (9)
- Methicillin-Resistant Staphylococcus aureus (MRSA) (3)
- Mortality (3)
- Neurological Disorders (1)
- Newborns/Infants (2)
- Nursing (1)
- Nursing Homes (1)
- Nutrition (1)
- Obesity (1)
- Outcomes (6)
- Pain (3)
- Patient-Centered Healthcare (1)
- Patient-Centered Outcomes Research (16)
- Patient Experience (1)
- Patient Safety (5)
- Patient Self-Management (2)
- Pneumonia (1)
- Practice Patterns (3)
- Pressure Ulcers (1)
- Prevention (4)
- Primary Care (2)
- Provider (1)
- Provider: Nurse (1)
- Provider: Physician (1)
- Quality Indicators (QIs) (1)
- Quality Measures (2)
- Quality of Care (1)
- Quality of Life (12)
- Racial and Ethnic Minorities (5)
- Research Methodologies (4)
- Respiratory Conditions (2)
- Risk (11)
- Screening (1)
- (-) Skin Conditions (121)
- Sleep Problems (11)
- Social Media (1)
- Surgery (1)
- Tobacco Use (1)
- Treatments (2)
- Urinary Tract Infection (UTI) (1)
- Vaccination (2)
AHRQ Research Studies
Sign up: AHRQ Research Studies Email updates
Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
76 to 100 of 121 Research Studies DisplayedFelix HC, Bradway C, Bird TM
Safety of obese persons in nursing homes.
This paper discusses the emergence of obese persons as a vulnerable group in the nursing home community. The authors discuss the special needs of this population including that obese residents require special protocols, trained staff, and appropriately sized equipment to prevent and treat skin breakdown.
AHRQ-funded; HS025703.
Citation: Felix HC, Bradway C, Bird TM .
Safety of obese persons in nursing homes.
Med Care 2018 Dec;56(12):1032-34. doi: 10.1097/mlr.0000000000000997..
Keywords: Long-Term Care, Obesity, Nursing Homes, Patient Safety, Skin Conditions
Kwa MC, Silverberg JI, Ardalan K
Inpatient burden of juvenile dermatomyositis among children in the United States.
The purpose of this study was to determine the prevalence and risk factors for hospitalization with juvenile dermatomyositis and assess inpatient burden of juvenile dermatomyositis (JDM). The study authors found that JDM contributes to both increased length of hospitalization and inpatient cost of care. Non-Medicaid government insurance was associated with higher rates of hospitalization for JDM while Hispanic and other non-white racial/ethnic groups demonstrated increased length of stay and cost of care.
AHRQ-funded; HS023011.
Citation: Kwa MC, Silverberg JI, Ardalan K .
Inpatient burden of juvenile dermatomyositis among children in the United States.
Pediatr Rheumatol Online J 2018 Nov 13;16(1):70. doi: 10.1186/s12969-018-0286-1..
Keywords: Children/Adolescents, Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Skin Conditions
Thorlacius L, Ingram JR, Villumsen B
A core domain set for hidradenitis suppurativa trial outcomes: an international Delphi process.
This article describes the outcome of six stakeholder groups participating in a Delphi process to create a core outcomes set (COS) for hidradenitis suppurative (HS) research. Five anonymous e-Delphi rounds and four face-to-face consensus meetings were conducted. A total of 41 patients and 52 healthcare professionals (HCPs) from 19 countries and 4 continents participated. The consensus adopted included five domains were approved: disease course, physical signs, HS-specific quality of life, pain, and global assessments.
AHRQ-funded; HS024585.
Citation: Thorlacius L, Ingram JR, Villumsen B .
A core domain set for hidradenitis suppurativa trial outcomes: an international Delphi process.
Br J Dermatol 2018 Sep;179(3):642-50. doi: 10.1111/bjd.16672..
Keywords: Skin Conditions, Health Services Research (HSR), Research Methodologies, Quality of Life
Li JC, Fishbein A, Singam V
Sleep disturbance and sleep-related impairment in adults with atopic dermatitis: a cross-sectional study.
The aim of this prospective online questionnaire-based study was to determine the relationship between atopic dermatitis (AD) severity, sleep disturbance (SD), and sleep-related impairment (SRI). The investigators concluded that their study suggests that SD and SRI are common in adults with AD, particularly those with severe diseases. They suggest that sleep disturbances and SRI should be considered when assessing burden of AD and therapeutic decisions.
AHRQ-funded; HS023011.
Citation: Li JC, Fishbein A, Singam V .
Sleep disturbance and sleep-related impairment in adults with atopic dermatitis: a cross-sectional study.
Dermatitis 2018 Sep/Oct;29(5):270-77. doi: 10.1097/der.0000000000000401..
Keywords: Skin Conditions, Sleep Problems
Silverberg JI, Vakharia PP, Chopra R
Phenotypical differences of childhood- and adult-onset atopic dermatitis.
This prospective study of adult- versus childhood-onset atopic dermatitis (AD) analyzed phenotypical differences with 356 adults with AD. In that sample, 41.9% reported adult-onset, with 24.4% after the age of 50. Adult-onset was associated with being born outside the US, but not sex, race/ethnicity, current smoking status, or alcohol consumption. Most adult-onset AD was associated with a high probability of lesions on for the hands and/or head/neck.
AHRQ-funded; HS023011.
Citation: Silverberg JI, Vakharia PP, Chopra R .
Phenotypical differences of childhood- and adult-onset atopic dermatitis.
J Allergy Clin Immunol Pract 2018 Jul - Aug;6(4):1306-12. doi: 10.1016/j.jaip.2017.10.005.
.
.
Keywords: Skin Conditions, Children/Adolescents
Owen JL, Vakharia PP, Silverberg JI
The role and diagnosis of allergic contact dermatitis in patients with atopic dermatitis.
Recent systematic reviews have suggested that allergic contact dermatitis (ACD) is a significant clinical problem in both children and adults with atopic dermatitis (AD). The authors review the clinical scenarios where patch testing is indicated in AD. In addition, they review the contraindications, preferred patch-testing series, pitfalls, and challenges determining the relevance of positive patch-test reactions in AD patients.
AHRQ-funded; HS023011.
Citation: Owen JL, Vakharia PP, Silverberg JI .
The role and diagnosis of allergic contact dermatitis in patients with atopic dermatitis.
Am J Clin Dermatol 2018 Jun;19(3):293-302. doi: 10.1007/s40257-017-0340-7.
.
.
Keywords: Diagnostic Safety and Quality, Skin Conditions
Vakharia PP, Chopra R, Sacotte R
Severity strata for five patient-reported outcomes in adults with atopic dermatitis.
Several patient-reported outcomes have been used to assess the burden of atopic dermatitis (AD). Some are disease specific, such as the Patient-Oriented Eczema Measure (POEM), while others pertain to itch, for example the numerical rating scale (NRS)-itch, ItchyQoL and 5-D itch, or dermatological disease in general, for example the Dermatology Life Quality Index (DLQI). The purpose of this study was to confirm previously developed strata for POEM, DLQI and raw ItchyQoL, and develop strata for the NRS-itch, mean ItchyQoL and 5-D itch scale for use in adults with AD.
AHRQ-funded; HS023011.
Citation: Vakharia PP, Chopra R, Sacotte R .
Severity strata for five patient-reported outcomes in adults with atopic dermatitis.
Br J Dermatol 2018 Apr;178(4):925-30. doi: 10.1111/bjd.16078..
Keywords: Outcomes, Patient-Centered Outcomes Research, Quality of Life, Skin Conditions
Thorlacius L, Garg A, Ingram JR
Towards global consensus on core outcomes for hidradenitis suppurativa research: an update from the HISTORIC consensus meetings I and II.
This article describes the outcome of two in-person consensus meetings to create a core outcomes set (COS) for hidradenitis suppurative (HS) research. Forty-one individuals from 13 countries and 4 continents were included. The list of items discussed had been developed from patient interviews, a systematic literature review and a healthcare professional survey. Nine items were excluded and seven domains were approved which included: disease course, physical signs, HS-specific quality of life, satisfaction, symptoms, pain and global assessments.
AHRQ-funded; HS024585.
Citation: Thorlacius L, Garg A, Ingram JR .
Towards global consensus on core outcomes for hidradenitis suppurativa research: an update from the HISTORIC consensus meetings I and II.
Br J Dermatol 2018 Mar;178(3):715-21. doi: 10.1111/bjd.16093..
Keywords: Evidence-Based Practice, Health Services Research (HSR), Outcomes, Research Methodologies, Skin Conditions
Hsu DY, Shinkai K, Silverberg JI
Epidemiology of eczema herpeticum in hospitalized U.S. children: analysis of a nationwide cohort.
This study used data from the Nationwide Inpatient Sample 2002-2012 to determine incidence, risk factors, comorbidities, costs, length of stay, and mortality in hospitalized children with Eczema herpeticum (EH). A higher risk was associated with younger age and non-white ethnicity (Asian in particular). However there was less frequency of hospitalization associated with lower income quartiles. The mortality incidence was 0.1%.
AHRQ-funded; HS023011.
Citation: Hsu DY, Shinkai K, Silverberg JI .
Epidemiology of eczema herpeticum in hospitalized U.S. children: analysis of a nationwide cohort.
J Invest Dermatol 2018 Feb;138(2):265-72. doi: 10.1016/j.jid.2017.08.039..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Healthcare Costs, Hospitalization, Skin Conditions
Fishbein AB, Mueller K, Kruse L
Sleep disturbance in children with moderate/severe atopic dermatitis: a case-control study.
The researchers sought to characterize sleep in a cohort of children with moderate-to-severe atopic dermatitis (AD) and to determine methods for assessment of sleep disturbance. In nineteen patients and nineteen controls, they found that patients with AD experienced wake after sleep onset (WASO) for 103 plus or minus 55 minutes as compared with 50 plus or minus 27 minutes in the controls. They had a higher frequency of restless sleep, daytime sleepiness, difficulty falling back to sleep at night, and teacher-reported daytime sleepiness. They concluded that children with moderate-to-severe AD experience more WASO and lower sleep efficiency than healthy controls but similar bedtime and wake time, sleep duration, and sleep onset latency.
AHRQ-funded; HS023011.
Citation: Fishbein AB, Mueller K, Kruse L .
Sleep disturbance in children with moderate/severe atopic dermatitis: a case-control study.
J Am Acad Dermatol 2018 Feb;78(2):336-41. doi: 10.1016/j.jaad.2017.08.043.
.
.
Keywords: Children/Adolescents, Children/Adolescents, Skin Conditions, Sleep Problems
Vakharia PP, Chopra R, Silverberg JI
Systematic review of diagnostic criteria used in atopic dermatitis randomized controlled trials.
This study sought to determine the most commonly used atopic dermatitis diagnostic criteria in randomized controlled trials internationally. The results highlighted the lack of uniformity and documentation of atopic dermatitis diagnostic criteria in randomized controlled trials for atopic dermatitis. The investigators recommended harmonizing the diagnostic criteria for atopic dermatitis in future randomized controlled trials.
AHRQ-funded; HS023011.
Citation: Vakharia PP, Chopra R, Silverberg JI .
Systematic review of diagnostic criteria used in atopic dermatitis randomized controlled trials.
Am J Clin Dermatol 2018 Feb;19(1):15-22. doi: 10.1007/s40257-017-0299-4..
Keywords: Diagnostic Safety and Quality, Patient-Centered Outcomes Research, Research Methodologies, Skin Conditions
Hogan PG, Rodriguez M, Spenner AM
Impact of systemic antibiotics on staphylococcus aureus colonization and recurrent skin infection.
This study found that systemic antibiotics, as part of acute skin and soft tissue infection (SSTI) management in conjunction with incision and drainage, impacted S. aureus colonization, thus contributing to a decreased incidence of recurrent SSTI. The mechanism by which clindamycin differentially affects colonization and recurrent SSTI compared to trimethoprim-sulfamethoxazole (TMP-SMX) warrants further study.
AHRQ-funded; HS021736; HS024269.
Citation: Hogan PG, Rodriguez M, Spenner AM .
Impact of systemic antibiotics on staphylococcus aureus colonization and recurrent skin infection.
Clin Infect Dis 2018 Jan 6;66(2):191-97. doi: 10.1093/cid/cix754.
.
.
Keywords: Antibiotics, Children/Adolescents, Healthcare-Associated Infections (HAIs), Patient Safety, Skin Conditions
Kwa MC, Silverberg JI
Association between inflammatory skin disease and cardiovascular and cerebrovascular co-morbidities in US adults: analysis of Nationwide Inpatient Sample data.
The objective of this study was to determine whether these inflammatory skin diseases are associated with increased cardiovascular/cerebrovascular risk and/or disease. It concluded that atopic dermatitis or eczema (AD-E), pemphigus, bullous pemphigoid (BP), and hidradenitis were all associated with increased cardiovascular and cerebrovascular risk, especially at younger age.
AHRQ-funded; HS023011.
Citation: Kwa MC, Silverberg JI .
Association between inflammatory skin disease and cardiovascular and cerebrovascular co-morbidities in US adults: analysis of Nationwide Inpatient Sample data.
Am J Clin Dermatol 2017 Dec;18(6):813-23. doi: 10.1007/s40257-017-0293-x.
.
.
Keywords: Cardiovascular Conditions, Healthcare Cost and Utilization Project (HCUP), Risk, Skin Conditions
Vakharia PP, Chopra R, Sacotte R
Burden of skin pain in atopic dermatitis.
This study sought to characterize the patient burden of skin pain in AD. It found that twenty-four (16.8 percent) patients thought the skin pain was part of their itch, 16 (11.2 percent) from scratching, and 77 (72.0 percent) from both. Patients with skin pain were more likely to describe their itch using terms that resembled neuropathic pain.
AHRQ-funded; HS023011.
Citation: Vakharia PP, Chopra R, Sacotte R .
Burden of skin pain in atopic dermatitis.
Ann Allergy Asthma Immunol 2017 Dec;119(6):548-52.e3. doi: 10.1016/j.anai.2017.09.076.
.
.
Keywords: Chronic Conditions, Pain, Quality of Life, Skin Conditions
Kwa L, Kwa MC, Silverberg JI
Cardiovascular comorbidities of pediatric psoriasis among hospitalized children in the United States.
This study sought to determine if there is an association between pediatric psoriasis and cardiovascular comorbidities. It found that in multivariate survey logistic regression models adjusting for age, sex, and race/ethnicity, pediatric psoriasis was significantly associated with 5 of 10 cardiovascular comorbidities.
AHRQ-funded; HS023011.
Citation: Kwa L, Kwa MC, Silverberg JI .
Cardiovascular comorbidities of pediatric psoriasis among hospitalized children in the United States.
J Am Acad Dermatol 2017 Dec;77(6):1023-29. doi: 10.1016/j.jaad.2017.08.034.
.
.
Keywords: Cardiovascular Conditions, Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Skin Conditions
Chopra R, Vakharia PP, Sacotte R
Relationship between EASI and SCORAD severity assessments for atopic dermatitis.
This research letter discussed the relationship between Eczema Area and Severity Index (EASI) and Scoring AD (SOCRAD) severity assessments for atopic dermatitis. The investigators performed a prospective, dermatology practice–based, observational study to determine the relationship between EASI and SCORAD.
AHRQ-funded; HS023011.
Citation: Chopra R, Vakharia PP, Sacotte R .
Relationship between EASI and SCORAD severity assessments for atopic dermatitis.
J Allergy Clin Immunol 2017 Dec;140(6):1708-10.e1. doi: 10.1016/j.jaci.2017.04.052.
.
.
Keywords: Skin Conditions
Chopra R, Vakharia PP, Sacotte R
Efficacy of bleach baths in reducing severity of atopic dermatitis: a systematic review and meta-analysis.
This study sought to determine the efficacy of bleach vs water baths at decreasing atopic dermatitis (AD) severity. In pooled analyses, there were no significant differences observed between bleach vs water baths at 4 weeks vs baseline for the Eczema Area and Severity Index. Although bleach baths are effective in decreasing AD severity, they do not appear to be more effective than water baths alone.
AHRQ-funded; HS023011.
Citation: Chopra R, Vakharia PP, Sacotte R .
Efficacy of bleach baths in reducing severity of atopic dermatitis: a systematic review and meta-analysis.
Ann Allergy Asthma Immunol 2017 Nov;119(5):435-40. doi: 10.1016/j.anai.2017.08.289.
.
.
Keywords: Comparative Effectiveness, Patient-Centered Outcomes Research, Skin Conditions
Gianfrancesco MA, Schmajuk G, Haserodt S
Hydroxychloroquine dosing in immune-mediated diseases: implications for patient safety.
Evidence suggests that hydroxychloroquine (HCQ) retinal toxicity is more common than previously thought. Adhering to careful weight-based dosing can significantly reduce the risk of this adverse event and is recommended in recent guidelines. The study authors used electronic health record data from a large health system to examine HCQ dosing over a 5-year period and identify risk factors associated with higher dosage of HCQ.
AHRQ-funded; HS024412.
Citation: Gianfrancesco MA, Schmajuk G, Haserodt S .
Hydroxychloroquine dosing in immune-mediated diseases: implications for patient safety.
Rheumatol Int 2017 Oct;37(10):1611-18. doi: 10.1007/s00296-017-3782-6..
Keywords: Adverse Drug Events (ADE), Patient Safety, Risk, Skin Conditions
Kwa MC, Ardalan K, Laumann AE
Predictors of hospitalization, length of stay and costs of care among adults with dermatomyositis in the United States.
The researchers sought to determine the prevalence and risk factors for hospitalization with dermatomyositis and to assess inpatient burden of dermatomyositis. They concluded that there is a significant and increasing inpatient burden for dermatomyositis in the US. Also, there appear to be racial differences as non-whites have higher prevalence of admission, increased length of stay and cost of care.
AHRQ-funded; HS023011.
Citation: Kwa MC, Ardalan K, Laumann AE .
Predictors of hospitalization, length of stay and costs of care among adults with dermatomyositis in the United States.
Arthritis Care Res 2017 Sep;69(9):1391-99. doi: 10.1002/acr.23190.
.
.
Keywords: Healthcare Cost and Utilization Project (HCUP), Hospitalization, Health Insurance, Skin Conditions
Zhang M, Silverberg JI, Kaffenberger BH
Prescription patterns and costs of acne/rosacea medications in Medicare patients vary by prescriber specialty.
The researchers described the medications used for treating acne/rosacea in the Medicare population and evaluated differences in costs between specialties. They concluded that costs of prescriptions for acne/rosacea from specialists are higher than those from primary care physicians and could be reduced by choosing generic and less expensive options.
AHRQ-funded; HS023011.
Citation: Zhang M, Silverberg JI, Kaffenberger BH .
Prescription patterns and costs of acne/rosacea medications in Medicare patients vary by prescriber specialty.
J Am Acad Dermatol 2017 Sep;77(3):448-55.e2. doi: 10.1016/j.jaad.2017.04.1127.
.
.
Keywords: Medication, Skin Conditions, Healthcare Costs, Medicare, Elderly
Greenhawt M, Fleischer DM, Chan ES
LEAPing through the looking glass: secondary analysis of the effect of skin test size and age of introduction on peanut tolerance after early peanut introduction.
This study explored relationships between peanut tolerance, baseline peanut/egg sensitization, eczema severity/duration, age of introduction, gender, and race. It concluded that increasing peanut wheal size predicted peanut tolerance only in the avoidance arm. Peanut introduction between 6 and 11 months of age was associated with the highest rates of peanut tolerance, questioning the 'urgency' of introduction before 6 months.
AHRQ-funded; HS024599.
Citation: Greenhawt M, Fleischer DM, Chan ES .
LEAPing through the looking glass: secondary analysis of the effect of skin test size and age of introduction on peanut tolerance after early peanut introduction.
Allergy 2017 Aug;72(8):1254-60. doi: 10.1111/all.13100.
.
.
Keywords: Evidence-Based Practice, Nutrition, Skin Conditions, Patient-Centered Outcomes Research
Narla S, Hsu DY, Thyssen JP
Inpatient financial burden of atopic dermatitis in the United States.
Little is known about the inpatient burden of atopic dermatitis (AD). The researchers sought to determine some risk factors and financial-burden of hospitalizations for AD in the US. They found that the high prevalence of hospitalization resulted in total inpatient costs of $8,288,083 per-year for adults and $3,333,868 per-year for children. In conclusion, there is a substantial inpatient financial-burden of AD in the US.
AHRQ-funded; HS023011.
Citation: Narla S, Hsu DY, Thyssen JP .
Inpatient financial burden of atopic dermatitis in the United States.
J Invest Dermatol 2017 Jul;137(7):1461-67. doi: 10.1016/j.jid.2017.02.975.
.
.
Keywords: Healthcare Cost and Utilization Project (HCUP), Skin Conditions, Healthcare Costs, Hospitalization
Silverberg JI
Selected comorbidities of atopic dermatitis: atopy, neuropsychiatric, and musculoskeletal disorders.
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease with substantial morbidity and quality of life impairment. This review summarizes recent developments in the atopic and neuropsychiatric comorbidities of AD. For example, it concludes that persons with AD appear to be at higher risk for multiple neuropsychiatric disorders, including depression, attention-deficit/hyperactivity disorder, speech disorders in childhood, headaches, and seizures.
AHRQ-funded; HS023011.
Citation: Silverberg JI .
Selected comorbidities of atopic dermatitis: atopy, neuropsychiatric, and musculoskeletal disorders.
Clin Dermatol 2017 Jul - Aug;35(4):360-66. doi: 10.1016/j.clindermatol.2017.03.008.
.
.
Keywords: Skin Conditions, Chronic Conditions, Behavioral Health, Quality of Life, Children/Adolescents
Hsu DY, Dalal P, Sable KA
Validation of International Classification of Disease Ninth Revision codes for atopic dermatitis.
This study sought to validate the use of ICD-9-CM codes for identifying atopic dermatitis. It found that in the outpatient setting, the ICD-9-CM codes 691.8 and 692.9 alone have poor positive predictive value (PPV). Incorporation of diagnoses of asthma, hay fever, and food allergy improves PPV and specificity. In the inpatient setting, a primary discharge diagnosis of 691.8 had excellent PPV.
AHRQ-funded; HS023011.
Citation: Hsu DY, Dalal P, Sable KA .
Validation of International Classification of Disease Ninth Revision codes for atopic dermatitis.
Allergy 2017 Jul;72(7):1091-95. doi: 10.1111/all.13113.
.
.
Keywords: Data, Diagnostic Safety and Quality, Skin Conditions
Daum RS, Miller LG, Immergluck L
A placebo-controlled trial of antibiotics for smaller skin abscesses.
The authors evaluated the appropriate management of uncomplicated skin abscesses in the era of community-associated methicillin-resistant Staphylococcus aureus (MRSA). They concluded that, compared with incision and drainage alone, clindamycin or TMP-SMX in conjunction with incision and drainage improves short-term outcomes in patients who have a simple abscess. This benefit must be weighed against the known side-effect profile of these antimicrobials.
AHRQ-funded; HS024338.
Citation: Daum RS, Miller LG, Immergluck L .
A placebo-controlled trial of antibiotics for smaller skin abscesses.
N Engl J Med 2017 Jun 29;376(26):2545-55. doi: 10.1056/NEJMoa1607033.
.
.
Keywords: Antibiotics, Community-Acquired Infections, Skin Conditions