National Healthcare Quality and Disparities Report
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Topics
- Adverse Drug Events (ADE) (1)
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- Evidence-Based Practice (1)
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- Health Literacy (1)
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- (-) Heart Disease and Health (11)
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- Outcomes (1)
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- Patient-Centered Outcomes Research (3)
- Patient Adherence/Compliance (1)
- (-) Quality of Life (11)
- Registries (1)
- Sex Factors (1)
- Shared Decision Making (1)
- Telehealth (2)
- Transitions of Care (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 11 of 11 Research Studies DisplayedYang G, Zhang M, Zhou S
Incompleteness of health-related quality of life assessments before left ventricular assist device implant: a novel quality metric.
Investigators hypothesized that pre-implant health-related quality of life (HRQOL) incompleteness in The Society of Thoracic Surgeons' Intermacs registry for patients undergoing left ventricular assist device (LVAD) implantation predicts 90-day outcomes. They found that HRQOL incompleteness at high-rate hospitals was more often due to administrative reasons and less likely due to patient reasons. Increases in the adjusted pre-implant incompleteness rates were significantly associated with higher risk of infection-related mortality, infection, and renal dysfunction. They concluded that hospital adjusted pre-implant HRQOL incompleteness was predictive of 90-day post-implant outcomes and may serve as a novel quality metric.
AHRQ-funded; HS026003.
Citation: Yang G, Zhang M, Zhou S .
Incompleteness of health-related quality of life assessments before left ventricular assist device implant: a novel quality metric.
J Heart Lung Transplant 2022 Oct;41(10):1520-28. doi: 10.1016/j.healun.2022.07.001..
Keywords: Quality of Life, Medical Devices, Heart Disease and Health, Cardiovascular Conditions
Ahmad FS, Jackson KL, Yount SE
The development and initial validation of the PROMIS®+HF-27 and PROMIS+HF-10 profiles.
This paper describes the continued refinement of the PROMIS®-Plus-HF (PROMIS+HF) profile measure, including universal and HF-specific items, to develop shorter PROMIS+HF profiles intended for research and clinical use. The authors developed the PROMIS+HF-27 and PROMIS+HF-10 profiles with summary scores (0-100) for overall, physical, mental, and social health. In a cross-sectional sample (n = 600), they measured internal consistency reliability (Cronbach's alpha and Spearman-Brown), test-retest reliability (intraclass coefficient; n = 100), known-groups validity via New York Heart Association (NYHA) class, and convergent validity with Kansas City Cardiomyopathy Questionnaire (KCCQ) scores. They also evaluated responsiveness of baseline/follow-up scores in a longitudinal sample of 75 by calculating mean differences and Cohen’s d and comparing with paired t-tests. PROMIS+HF-27 scores showed good to excellent internal consistency and acceptable to good for PROMIS+HF-10 scores. Good psychometric characteristics were shown for both measures with evidence of responsiveness for overall and physical health.
AHRQ-funded; HS026385.
Citation: Ahmad FS, Jackson KL, Yount SE .
The development and initial validation of the PROMIS®+HF-27 and PROMIS+HF-10 profiles.
ESC Heart Fail 2022 Jul 15;9(5):3380-92. doi: 10.1002/ehf2.14061..
Keywords: Heart Disease and Health, Cardiovascular Conditions, Quality of Life, Patient-Centered Outcomes Research
Wells R, Dionne-Odom JN, Azuero A
Examining adherence and dose effect of an early palliative care intervention for advanced heart failure patients.
The objective of this study was to examine the "dose" effect of PC intervention completion vs. noncompletion on quality of life (QoL) and healthcare use in patients with advanced heart failure (HF) over 32 weeks. The investigators concluded that higher intervention completion rates of an early PC intervention was associated with QoL improvements in patients with advanced HF.
AHRQ-funded; HS013852.
Citation: Wells R, Dionne-Odom JN, Azuero A .
Examining adherence and dose effect of an early palliative care intervention for advanced heart failure patients.
J Pain Symptom Manage 2021 Sep;62(3):471-81. doi: 10.1016/j.jpainsymman.2021.01.136..
Keywords: Palliative Care, Heart Disease and Health, Cardiovascular Conditions, Quality of Life, Telehealth, Health Information Technology (HIT)
Ahmad FS, Kallen MA, Schifferdecker KE
Development and initial validation of the PROMIS(R)-Plus-HF profile measure.
This paper describes the efforts to develop and validate the PROMIS®-Plus-HF (Patient-Reported Outcomes Measurement Information System®-Plus-Heart Failure) profile measure. The authors conducted 8 focus groups with 61 patients with HF and phone interviews with 10 HF clinicians. They tested the measure with a 600-patient sample. Validity was analyzed and confirmed using Pearson r and Spearman rho correlations with Kansas City Cardiomyopathy Questionnaire subscores. The measure consists of 86 items across 18 domains.
AHRQ-funded; HS026385.
Citation: Ahmad FS, Kallen MA, Schifferdecker KE .
Development and initial validation of the PROMIS(R)-Plus-HF profile measure.
Circ Heart Fail 2019 Jun;12(6):e005751. doi: 10.1161/circheartfailure.118.005751.
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Keywords: Patient-Centered Outcomes Research, Heart Disease and Health, Cardiovascular Conditions, Shared Decision Making, Quality of Life, Health Status
Uy V, Hays RD, Xu JJ
Do the unlabeled response categories of the Minnesota Living with Heart Failure Questionnaire satisfy the monotonicity assumption of simple-summated scoring?
Half of the 21-item Minnesota Living with Heart Failure Questionnaire (MLHFQ) response categories are labeled (0 = No, 1 = Very little, 5 = Very much) and half are not (2, 3, and 4). In this study, the investigators hypothesized that the unlabeled response options would not be more likely to be chosen at some place along the scale continuum than other response options and, therefore, not satisfy the monotonicity assumption of simple-summated scoring.
AHRQ-funded; HS019311.
Citation: Uy V, Hays RD, Xu JJ .
Do the unlabeled response categories of the Minnesota Living with Heart Failure Questionnaire satisfy the monotonicity assumption of simple-summated scoring?
Qual Life Res 2020 May;29(5):1349-60. doi: 10.1007/s11136-020-02422-8..
Keywords: Heart Disease and Health, Cardiovascular Conditions, Chronic Conditions, Quality of Life
Bachmann JM, Goggins KM, Nwosu SK
Perceived health competence predicts health behavior and health-related quality of life in patients with cardiovascular disease.
The authors sought to evaluate the effect of perceived health competence on health behavior and health-related quality of life. They found that perceived health competence was highly associated with health behaviors and health-related quality of life, while low perceived health competence was associated with a decrease in health-related quality of life between hospitalization and 90 days after discharge. They concluded that perceived health competence predicts health behavior and health-related quality of life in patients hospitalized with cardiovascular disease as well as change in health-related quality of life after discharge.
AHRQ-funded; HS022990.
Citation: Bachmann JM, Goggins KM, Nwosu SK .
Perceived health competence predicts health behavior and health-related quality of life in patients with cardiovascular disease.
Patient Educ Couns 2016 Dec;99(12):2071-79. doi: 10.1016/j.pec.2016.07.020.
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Keywords: Cardiovascular Conditions, Heart Disease and Health, Health Literacy, Patient Adherence/Compliance, Quality of Life
Ware JE, Jr., Gandek B, Allison J
The validity of disease-specific quality of life attributions among adults with multiple chronic conditions.
The objective of this study was to evaluate the convergent and discriminant validity of QOL attributions to specific diseases among adults with multiple chronic conditions (MCC). It concluded that, collectively, convergent and discriminant test results support the construct validity of disease-specific QOL impact attributions across MCC within the eight pre-identified conditions.
AHRQ-funded; HS023117.
Citation: Ware JE, Jr., Gandek B, Allison J .
The validity of disease-specific quality of life attributions among adults with multiple chronic conditions.
Int J Stat Med Res 2016;5(1):17-40..
Keywords: Quality of Life, Chronic Conditions, Arthritis, Kidney Disease and Health, Heart Disease and Health
Piccini JP, Simon DN, Steinberg BA
Differences in clinical and functional outcomes of atrial fibrillation in women and men: two-year results from the ORBIT-AF Registry.
The purpose of this paper was to determine whether symptoms, quality of life, treatment, and outcomes differ between women and men with atrial fibrillation (AF). The authors found that women with AF have more symptoms and worse quality of life, lower risk-adjusted all-cause and cardiovascular death compared with men, but higher stroke rates.
AHRQ-funded; HS021092.
Citation: Piccini JP, Simon DN, Steinberg BA .
Differences in clinical and functional outcomes of atrial fibrillation in women and men: two-year results from the ORBIT-AF Registry.
JAMA Cardiol 2016 Jun 1;1(3):282-91. doi: 10.1001/jamacardio.2016.0529.
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Keywords: Heart Disease and Health, Cardiovascular Conditions, Sex Factors, Patient-Centered Outcomes Research, Outcomes, Quality of Life, Registries, Evidence-Based Practice
Ong MK, Romano PS, Edgington S
Effectiveness of remote patient monitoring after discharge of hospitalized patients with heart failure: the better effectiveness after transition-heart failure (BEAT-HF) randomized clinical trial.
The researchers evaluated the effectiveness of a care transition intervention using remote patient monitoring in reducing 180-day all-cause readmissions among a broad population of older adults hospitalized with HF. Theyn found that intervention and usual care groups did not differ significantly in readmissions for any cause 180 days after discharge.
AHRQ-funded; HS019311.
Citation: Ong MK, Romano PS, Edgington S .
Effectiveness of remote patient monitoring after discharge of hospitalized patients with heart failure: the better effectiveness after transition-heart failure (BEAT-HF) randomized clinical trial.
JAMA Intern Med 2016 Mar;176(3):310-8. doi: 10.1001/jamainternmed.2015.7712.
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Keywords: Heart Disease and Health, Hospital Readmissions, Telehealth, Quality of Life, Hospital Discharge
Dharmarajan K, Chaudhry SI
New approaches to reduce readmissions in patients with heart failure.
The authors discuss a study by Ong and colleagues that presents the results of Better Effectiveness After Transition–Heart Failure (BEATHF), a randomized clinical trial of a combined telemonitoring and care transitions intervention to prevent readmission in patients with heart failure. The BEAT-HF intervention did not lower readmissions after hospitalization for heart failure.
AHRQ-funded; HS023554.
Citation: Dharmarajan K, Chaudhry SI .
New approaches to reduce readmissions in patients with heart failure.
JAMA Intern Med 2016 Mar;176(3):318-20. doi: 10.1001/jamainternmed.2015.7993.
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Keywords: Heart Disease and Health, Hospital Discharge, Hospital Readmissions, Quality of Life, Transitions of Care
Amin AP, Wang TY, McCoy L
Impact of bleeding on quality of life in patients on DAPT: insights from TRANSLATE-ACS.
This study sought to determine the incidence of post-percutaneous coronary intervention (PCI) bleeding that occurs on contemporary prolonged dual antiplatelet therapy (DAPT) and its impact on quality of life (QOL). Among patients undergoing PCI for acute myocardial infarction, bleeding during follow-up was associated with worse 6-month utility and QOL
AHRQ-funded; HS022481.
Citation: Amin AP, Wang TY, McCoy L .
Impact of bleeding on quality of life in patients on DAPT: insights from TRANSLATE-ACS.
J Am Coll Cardiol 2016 Jan 5;67(1):59-65. doi: 10.1016/j.jacc.2015.10.034.
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Keywords: Quality of Life, Heart Disease and Health, Adverse Drug Events (ADE), Adverse Events