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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedAlkhouri N, Almomani A, Le P
The prevalence of alcoholic and nonalcoholic fatty liver disease in adolescents and young adults in the United States: analysis of the NHANES database.
The purpose of this study was to evaluate the prevalence of non-alcoholic fatty liver disease (NAFLD) and alcohol-associated fatty liver disease (ALD) in a cohort of adolescents and young adults (AYAs) using transient elastography to directly measure hepatic steatosis and suspected fibrosis. AYA’s aged 15-39 years without viral hepatitis, pregnancy, or ALT/ AST greater than 500 U/L were included in the study. The researchers compared subjects with excessive alcohol consumption to those without and found that those with excessive alcohol consumption suspected ALD was present in 56.59% and suspected significant fibrosis was present in 12.3% and suspected advanced fibrosis was present in 6.31%. In subjects without excessive alcohol consumption, suspected NAFLD was present in 40.04%. In those with suspected NAFLD, suspected significant fibrosis was present in 31.07% and suspected advanced fibrosis was present in 20.15%. The study concluded that a significant percentage of AYAs are at risk for ALD and NAFLD and a subset of these subjects is at risk for significant fibrosis.
AHRQ-funded; HS026937.
Citation: Alkhouri N, Almomani A, Le P .
The prevalence of alcoholic and nonalcoholic fatty liver disease in adolescents and young adults in the United States: analysis of the NHANES database.
BMC Gastroenterol 2022 Jul 30;22(1):366. doi: 10.1186/s12876-022-02430-7..
Keywords: Children/Adolescents, Young Adults, Alcohol Use, Chronic Conditions