National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
101 to 108 of 108 Research Studies DisplayedMuntner P, Gutierrez OM, Zhao H
Validation study of medicare claims to identify older US adults with CKD using the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study.
The researchers compared characteristics and outcomes for individuals with chronic kidney disease (CKD) defined using laboratory measurements versus claims data from 6,982 study participants who had Medicare fee-for-service coverage. They found that CKD, whether identified using a claims-based algorithm or through estimated glomerular filtration rate or albumin-creatinine ratio measurements, is associated with increased risk for all-cause mortality and end-stage renal disease (ESRD).
AHRQ-funded; HS018517.
Citation: Muntner P, Gutierrez OM, Zhao H .
Validation study of medicare claims to identify older US adults with CKD using the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study.
Am J Kidney Dis 2015 Feb;65(2):249-58. doi: 10.1053/j.ajkd.2014.07.012.
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Am J Kidney Dis 2015 Feb;65(2):249-58. doi: 10.1053/j.ajkd.2014.07.012.
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Keywords: Kidney Disease and Health, Outcomes, Comparative Effectiveness, Kidney Disease and Health, Mortality
Montenovo MI, Dick AA, Hansen RN
Donor hepatitis C sero-status does not impact survival in liver transplantation.
The researchers sought to assess the impact of both donor and recipient HCV status on patient and graft survival. They found that the use of HCV+ grafts in HCV+ recipients is not associated with worse outcomes. They conclude that with the increase in HCV+patients awaiting an organ, more consideration should be given to HCV+ donors.
AHRQ-funded; HS021686.
Citation: Montenovo MI, Dick AA, Hansen RN .
Donor hepatitis C sero-status does not impact survival in liver transplantation.
Ann Transplant 2015 Jan 22;20:44-50. doi: 10.12659/aot.892530..
Keywords: Hepatitis, Comparative Effectiveness, Outcomes, Mortality
Tamirisa NP, Parmar AD, Vargas GM
Relative contributions of complications and failure to rescue on mortality in older patients undergoing pancreatectomy.
This study evaluated the relative contribution of overall postoperative complications and failure to rescue rates on the observed increased mortality in older patients undergoing pancreatic resection at specialized centers. The study found that patients 80 years and older had no difference in complication rates but higher failure to rescue rates compared to patients younger than 80.
AHRQ-funded; HS022134
Citation: Tamirisa NP, Parmar AD, Vargas GM .
Relative contributions of complications and failure to rescue on mortality in older patients undergoing pancreatectomy.
Ann Surg. 2016 Feb;263(2):385-91. doi: 10.1097/SLA.0000000000001093..
Keywords: Surgery, Mortality, Patient Safety, Quality of Care, Elderly
Faerber AE, Horvath R, Stillman C
Development and pilot feasibility study of a health information technology tool to calculate mortality risk for patients with asymptomatic carotid stenosis: the Carotid Risk Assessment Tool (CARAT).
The researchers describe the development of the CArotid Risk Assessment Tool (CARAT) into a 2-year mortality risk calculator within the electronic medical record. They integrated the tool into the clinical workflow, trained the clinical team to use the tool, and assessed the feasibility and acceptability of the tool in one clinic setting.
AHRQ-funded; HS021581.
Citation: Faerber AE, Horvath R, Stillman C .
Development and pilot feasibility study of a health information technology tool to calculate mortality risk for patients with asymptomatic carotid stenosis: the Carotid Risk Assessment Tool (CARAT).
BMC Med Inform Decis Mak 2015;15:20. doi: 10.1186/s12911-015-0141-y..
Keywords: Health Information Technology (HIT), Electronic Health Records (EHRs), Mortality, Risk
Cooper AB, Parmar AD, Riall TS
Does the use of neoadjuvant therapy for pancreatic adenocarcinoma increase postoperative morbidity and mortality rates?
The researchers used data from the NSQIP Pancreatectomy Demonstration Project (11/2011 to 12/2012) to identify patients with pancreatic adenocarcinoma who did and did not receive neoadjuvant therapy. They found that despite evidence for more extensive disease, patients receiving neoadjuvant therapy did not experience more complications. Neoadjuvant radiation was associated with lower pancreatic fistula rates.
AHRQ-funded; HS022134.
Citation: Cooper AB, Parmar AD, Riall TS .
Does the use of neoadjuvant therapy for pancreatic adenocarcinoma increase postoperative morbidity and mortality rates?
J Gastrointest Surg 2015 Jan;19(1):80-6; discussion 86-7. doi: 10.1007/s11605-014-2620-3..
Keywords: Cancer, Comparative Effectiveness, Patient-Centered Outcomes Research, Surgery, Mortality
Kastenberg ZJ, Lee HC, Profit J
Effect of deregionalized care on mortality in very low-birth-weight infants with necrotizing enterocolitis.
The study’s aims were to describe the current trend toward deregionalization and to test the hypothesis that infants with necrotizing enterocolitis represent a particularly high-risk subgroup of the VLBW population that would benefit from early identification, increased intensity of early management, and possible targeted triage to tertiary hospitals. It found that outcomes for VLBW infants continue to be suboptimal when they are not born into high-level, high-volume centers.
AHRQ-funded; HS000028.
Citation: Kastenberg ZJ, Lee HC, Profit J .
Effect of deregionalized care on mortality in very low-birth-weight infants with necrotizing enterocolitis.
JAMA Pediatr 2015 Jan;169(1):26-32. doi: 10.1001/jamapediatrics.2014.2085..
Keywords: Newborns/Infants, Labor and Delivery, Mortality, Neonatal Intensive Care Unit (NICU), Healthcare Delivery
Suckow BD, Kraiss LW, Schanzer A
Statin therapy after infrainguinal bypass surgery for critical limb ischemia is associated with improved 5-year survival.
The aim of this study was to determine the effect of long-term statin use after lower extremity bypass grafting on patient-related and graft-related outcomes. It found that statin therapy is associated with a 5-year survival benefit after lower extremity bypass in patients with critical limb ischemia. However, 1-year limb-related outcomes were not influenced by statin use in our large observational cohort of patients undergoing revascularization in New England.
AHRQ-funded; HS021581.
Citation: Suckow BD, Kraiss LW, Schanzer A .
Statin therapy after infrainguinal bypass surgery for critical limb ischemia is associated with improved 5-year survival.
J Vasc Surg 2015 Jan;61(1):126-33. doi: 10.1016/j.jvs.2014.05.093..
Keywords: Outcomes, Surgery, Mortality, Registries
Tien YY, Link BK, Brooks JM
Treatment of diffuse large B-cell lymphoma in the elderly: regimens without anthracyclines are common and not futile.
This study characterized treatment choices and compared the 3-year overall survival rates of 8262 Medicare beneficiaries diagnosed with diffuse large B-cell lymphoma in 2000 – 2006. It found that patients treated with anthracycline-containing regimens with rituximab have the highest survival rates when all available clinical features are accounted for.
AHRQ-funded; HS016094.
Citation: Tien YY, Link BK, Brooks JM .
Treatment of diffuse large B-cell lymphoma in the elderly: regimens without anthracyclines are common and not futile.
Leuk Lymphoma 2015 Jan;56(1):65-71. doi: 10.3109/10428194.2014.903589..
Keywords: Comparative Effectiveness, Medicare, Outcomes, Cancer, Mortality