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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedSun D, Simon GJ, Skube S
Causal phenotyping for susceptibility to cardiotoxicity from antineoplastic breast cancer medications.
Cardiotoxicity is a relatively common and particularly important adverse event caused by chemotherapy for breast cancer patients. The authors of this study propose three phenotyping algorithms to assess breast cancer patients' susceptibility to cardiotoxicity caused by five first-line antineoplastic drugs. The study demonstrates the potential utility of causal phenotyping.
AHRQ-funded; HS022085.
Citation: Sun D, Simon GJ, Skube S .
Causal phenotyping for susceptibility to cardiotoxicity from antineoplastic breast cancer medications.
AMIA Annu Symp Proc 2018 Apr 16;2017:1655-64..
Keywords: Adverse Drug Events (ADE), Cancer: Breast Cancer, Medication, Risk
Punglia RS, Jiang W, Lipsitz SR
Clinical risk score to predict likelihood of recurrence after ductal carcinoma in situ treated with breast-conserving surgery.
In this article, the investigators developed a score to provide individualized information about ipsilateral breast tumor recurrence risk to guide treatment decisions. The authors indicate that their simple, no-cost risk score may be used by patients and physicians to facilitate preference-based decision-making about ductal carcinoma in situ management informed by a more accurate understanding of risks.
AHRQ-funded; 29020050016I.
Citation: Punglia RS, Jiang W, Lipsitz SR .
Clinical risk score to predict likelihood of recurrence after ductal carcinoma in situ treated with breast-conserving surgery.
Breast Cancer Res Treat 2018 Feb;167(3):751-59. doi: 10.1007/s10549-017-4553-5..
Keywords: Cancer: Breast Cancer, Risk, Surgery, Patient-Centered Outcomes Research