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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedMiller PE, Pawar S, Vaccaro B
Predictive abilities of machine learning techniques may be limited by dataset characteristics: insights from the UNOS database.
This study compared using machine learning techniques to traditional prediction models for 1-year survival rates of heart transplant patients. The Unified Network for Organ Sharing (UNOS) was used to analyze data for adult patients undergoing cardiac transplantation from 1987 to 2014. The dataset was divided into 3 time periods based on geographic regions and major allocation adjustments. They used several different prediction methods including logistic regression, ridge regression, and regressions with LASSO (least absolute shrinkage and selection operator) and compared them with machine learning methodologies. There was no improvement found of 1-year survival predictions with machine learning compared to traditional prediction models.
AHRQ-funded; HS023000.
Citation: Miller PE, Pawar S, Vaccaro B .
Predictive abilities of machine learning techniques may be limited by dataset characteristics: insights from the UNOS database.
J Card Fail 2019 Jun;25(6):479-83. doi: 10.1016/j.cardfail.2019.01.018..
Keywords: Cardiovascular Conditions, Heart Disease and Health, Outcomes, Transplantation
Dunn T, Saeed MJ, Shpigel A
The association of preoperative cardiac stress testing with 30-day death and myocardial infarction among patients undergoing kidney transplantation.
This study examined whether the use of preoperative cardiac stress testing of patients undergoing kidney transplantation reduced 30-day- death and myocardial infarction post-transplantation. ESRD patients 40 years or older with primary Medicare insurance between 2006 and 2013 were identified using the United States Renal Data System. In a matched cohort of 17,304 patients, there was little difference in 30-day post-transplantation mortality and myocardial infarction between those receiving a stress test and those who did not.
AHRQ-funded; HS019455.
Citation: Dunn T, Saeed MJ, Shpigel A .
The association of preoperative cardiac stress testing with 30-day death and myocardial infarction among patients undergoing kidney transplantation.
PLoS One 2019 Feb;14(2):e0211161. doi: 10.1371/journal.pone.0211161..
Keywords: Transplantation, Kidney Disease and Health, Heart Disease and Health, Cardiovascular Conditions, Chronic Conditions, Risk, Surgery