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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedGovindarajan P, Shiboski S, Grimes B
Effect of acute stroke care regionalization on intravenous alteplase use in two urban counties.
Investigators sought to determine whether increasing access to primary stroke centers (regionalization) led to an increase in intravenous alteplase use in acute ischemic stroke patients. Studying two urban counties in the western region of US that regionalized acute stroke care, they found that in Santa Clara County, intravenous alteplase was administered to 1.7% of patients in the pre-regionalization period and 2.1% in the post-regionalization period, while in San Mateo County, the numbers were 1.3% and 3.2%, respectively. In the post-regionalization phase, San Mateo County had greater change in paramedic stroke detection, higher number of transports to primary stroke centers, and more frequent use of intravenous alteplase at stroke centers. They concluded that greater post-regionalization improvements in San Mateo County contributed to significantly improved county-level thrombolysis use than Santa Clara County.
AHRQ-funded; HS026207; HS017965.
Citation: Govindarajan P, Shiboski S, Grimes B .
Effect of acute stroke care regionalization on intravenous alteplase use in two urban counties.
Prehosp Emerg Care 2020 Jul-Aug;24(4):505-14. doi: 10.1080/10903127.2019.1679303..
Keywords: Stroke, Cardiovascular Conditions, Urban Health, Access to Care, Emergency Medical Services (EMS), Critical Care
Hsieh YH, Haukoos JS, Rothman RE
Validation of an abbreviated version of the Denver HIV Risk Score for prediction of HIV infection in an urban ED.
The researchers sought to evaluate the performance of a short version of the Denver HIV Risk Score in 2 urban emergency departments. They found that external validation resulted in good discrimination. The study cohort included 15,184 patients with newly diagnosed HIV infection.
AHRQ-funded; HS017526
Citation: Hsieh YH, Haukoos JS, Rothman RE .
Validation of an abbreviated version of the Denver HIV Risk Score for prediction of HIV infection in an urban ED.
Am J Emerg Med. 2014 Jul;32(7):775-9. doi: 10.1016/j.ajem.2014.02.043..
Keywords: Emergency Medical Services (EMS), Human Immunodeficiency Virus (HIV), Risk, Urban Health