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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedVouri SM, Schootman M, Strope SA
Differential prescribing of antimuscarinic agents in older adults with cognitive impairment.
The objective of this study was to describe the use of oral oxybutynin versus other antimuscarinics in older adults with documented cognitive impairment. Patients with cognitive impairment were 5 percent more likely to initiate another antimuscarinic versus oral oxybutynin. The proportion of patients with cognitive impairment initiated on oral oxybutynin increased from 24.1 percent in 2008 to 41.1 percent in 2011.
AHRQ-funded; HS019455.
Citation: Vouri SM, Schootman M, Strope SA .
Differential prescribing of antimuscarinic agents in older adults with cognitive impairment.
Drugs Aging 2018 Apr;35(4):321-31. doi: 10.1007/s40266-018-0531-9.
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Keywords: Adverse Drug Events (ADE), Elderly, Medication, Neurological Disorders
Gray SL, Hart LA, Perera S
Meta-analysis of interventions to reduce adverse drug reactions in older adults.
This review examined the effect of interventions to optimize medication use on adverse drug reactions (ADRs) in older adults. Thirteen randomized controlled trials involving 6,198 older adults were included in the review. It concluded that interventions designed to optimize medication use reduced the risk of any and serious ADRs in older adults.
AHRQ-funded; HS023779.
Citation: Gray SL, Hart LA, Perera S .
Meta-analysis of interventions to reduce adverse drug reactions in older adults.
J Am Geriatr Soc 2018 Feb;66(2):282-88. doi: 10.1111/jgs.15195.
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Keywords: Adverse Drug Events (ADE), Elderly, Medication: Safety, Medication, Patient Safety