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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 3 of 3 Research Studies DisplayedBourgi K, Jenkins CA, Rebeiro PF
Weight gain among treatment-naive persons with HIV starting integrase inhibitors compared to non-nucleoside reverse transcriptase inhibitors or protease inhibitors in a large observational cohort in the United States and Canada.
This study compared weight gain among persons with HIV (PWH) following different antiretroviral therapy (ART) drug classes. The cohort was part of the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). The 22,972 participants were 87% male and 41% white. Twenty percent started strand transfer inhibitor (INSTI), 31% started protease inhibitor (PI), and 49% started non-nucleoside reverse-transcriptase inhibitor (NNRTI)-based ART. Average weight gain was higher with INSTI-based regimens compared to NNRTI-based regimens or PI-based regimens.
AHRQ-funded; 90047713.
Citation: Bourgi K, Jenkins CA, Rebeiro PF .
Weight gain among treatment-naive persons with HIV starting integrase inhibitors compared to non-nucleoside reverse transcriptase inhibitors or protease inhibitors in a large observational cohort in the United States and Canada.
J Int AIDS Soc 2020 Apr;23(4):e25484. doi: 10.1002/jia2.25484.
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Keywords: Human Immunodeficiency Virus (HIV), Obesity: Weight Management, Obesity, Medication
Derose KP, Rios-Castillo I, Fulcar MA
Severe food insecurity is associated with overweight and increased body fat among people living with HIV in the Dominican Republic.
To explore the association between food insecurity and overweight and obesity among PLHIV in the Dominican Republic, the researchers conducted a cross-sectional study of 160 HIV-infected adults between March-December 2012. After controlling for age, gender, income, having children at home, education, and anti-retroviral therapy status, severe food insecurity was associated with increased body mass index (BMI) and body fat.
AHRQ-funded; HS000046.
Citation: Derose KP, Rios-Castillo I, Fulcar MA .
Severe food insecurity is associated with overweight and increased body fat among people living with HIV in the Dominican Republic.
AIDS Care 2018 Feb;30(2):182-90. doi: 10.1080/09540121.2017.1348597.
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Keywords: Human Immunodeficiency Virus (HIV), Nutrition, Obesity, Obesity: Weight Management, Social Determinants of Health
Herrin M, Tate JP, Akgun KM
Weight gain and incident diabetes among HIV-infected veterans initiating antiretroviral therapy compared with uninfected individuals.
The authors used data from the Veterans Aging Cohort Study to determine whether weight gain after antiretroviral therapy has a similar association with incident type 2 diabetes mellitus as weight gained among HIV-uninfected individuals. They found that weight gained during the first year after antiretroviral therapy initiation is associated with greater risk of diabetes mellitus than that among uninfected individuals.
AHRQ-funded; HS018372.
Citation: Herrin M, Tate JP, Akgun KM .
Weight gain and incident diabetes among HIV-infected veterans initiating antiretroviral therapy compared with uninfected individuals.
J Acquir Immune Defic Syndr 2016 Oct 1;73(2):228-36. doi: 10.1097/qai.0000000000001071.
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Keywords: Diabetes, Human Immunodeficiency Virus (HIV), Medication, Obesity: Weight Management