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Search All Research Studies
Topics
- Antibiotics (2)
- Care Management (1)
- Children/Adolescents (1)
- Diagnostic Safety and Quality (1)
- Evidence-Based Practice (1)
- (-) Guidelines (4)
- Infectious Diseases (1)
- Long-Term Care (1)
- Medication (1)
- Nursing Homes (1)
- Practice Patterns (1)
- Prevention (1)
- Screening (1)
- Shared Decision Making (2)
- U.S. Preventive Services Task Force (USPSTF) (1)
- (-) Urinary Tract Infection (UTI) (4)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 4 of 4 Research Studies DisplayedKistler CE, Wretman Zimmerman, S S
Overdiagnosis of urinary tract infections by nursing home clinicians versus a clinical guideline.
The purpose of this study was to examine the concordance between clinicians' diagnosis of suspected urinary tract infection (UTI) with a clinical guideline treated as the gold standard, in order to inform overprescribing and antibiotic stewardship in nursing homes. The authors conducted a cross-sectional web-based survey of a national convenience sample of nursing-home clinicians, including a discrete choice experiment with 19 randomly selected scenarios of nursing-home residents with possible UTIs. Responses were compared to the guideline. The results indicated that nursing-home clinicians tend to over-diagnose UTI. The authors concluded that this necessitates systems-based interventions to augment clinical decisionmaking.
AHRQ-funded; HS024519.
Citation: Kistler CE, Wretman Zimmerman, S S .
Overdiagnosis of urinary tract infections by nursing home clinicians versus a clinical guideline.
J Am Geriatr Soc 2022 Apr;70(4):1070-81. doi: 10.1111/jgs.17638..
Keywords: Nursing Homes, Long-Term Care, Urinary Tract Infection (UTI), Guidelines, Diagnostic Safety and Quality, Shared Decision Making
Henderson JT, Webber EM, Bean SI
Screening for asymptomatic bacteriuria in adults: updated evidence report and systematic review for the US Preventive Services Task Force.
Investigators systematically reviewed the benefits and harms of asymptomatic bacteriuria screening and treatment in adults, including during pregnancy, to inform the US Preventive Services Task Force. They found that screening and treatment for asymptomatic bacteriuria during pregnancy was associated with reduced rates of pyelonephritis and low birth weights, while benefits of asymptomatic bacteriuria treatment in nonpregnant adult populations were not found. Trial evidence was limited.
AHRQ-funded; 290201500007.
Citation: Henderson JT, Webber EM, Bean SI .
Screening for asymptomatic bacteriuria in adults: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2019 Sep 24;322(12):1195-205. doi: 10.1001/jama.2019.10060..
Keywords: Evidence-Based Practice, Guidelines, Infectious Diseases, Prevention, Screening, Urinary Tract Infection (UTI), U.S. Preventive Services Task Force (USPSTF)
Advanced Analytics Group of Pediatric Urology, ORC Personalized Medicine Group
Targeted workup after initial febrile urinary tract infection: using a novel machine learning model to identify children most likely to benefit from voiding cystourethrogram.
The authors sought to develop a model to predict the probability of recurrent urinary tract infection associated vesicoureteral reflux in children after an initial urinary tract infection. Their predictive model provided a promising performance to facilitate individualized treatment of children with an initial urinary tract infection and to identify those most likely to benefit from voiding cystourethrogram after the initial urinary tract infection. They conclude that this model would allow for more selective test application and increase yield while minimizing overuse.
AHRQ-funded; HS000063.
Citation: Advanced Analytics Group of Pediatric Urology, ORC Personalized Medicine Group .
Targeted workup after initial febrile urinary tract infection: using a novel machine learning model to identify children most likely to benefit from voiding cystourethrogram.
J Urol 2019 Jul;202(1):144-52. doi: 10.1097/ju.0000000000000186..
Keywords: Antibiotics, Care Management, Children/Adolescents, Guidelines, Medication, Urinary Tract Infection (UTI)
Durkin MJ, Keller M, Butler AM
An assessment of inappropriate antibiotic use and guideline adherence for uncomplicated urinary tract infections.
In 2011, The Infectious Diseases Society of America released a clinical practice guideline (CPG) that recommended short-course antibiotic therapy and avoidance of fluoroquinolones for uncomplicated urinary tract infections (UTIs). This study assessed whether the CPG had an impact on national antibiotic prescribing practices. The study found that CPG was not associated with a clinically meaningful change in national antibiotic prescribing practices for UTIs.
AHRQ-funded; HS019455.
Citation: Durkin MJ, Keller M, Butler AM .
An assessment of inappropriate antibiotic use and guideline adherence for uncomplicated urinary tract infections.
Open Forum Infect Dis 2018 Sep;5(9):ofy198. doi: 10.1093/ofid/ofy198..
Keywords: Antibiotics, Shared Decision Making, Guidelines, Practice Patterns, Urinary Tract Infection (UTI)