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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 4 of 4 Research Studies DisplayedKeenan KE, Rothberg MB, Herzig SJ
Association between opioids prescribed to medical inpatients with pain and long-term opioid use.
This study’s objective was to identify the association between opioid exposure during a medical hospitalization and opioid use 6 to 12 months later. This observational cohort study used electronic health record data from 10 hospitals in the Cleveland Clinic Health System in 2016. Eligible patients were opioid-naïve adults with pain 18 years and older. The authors estimated the odds of long-term opioid use (defined as ≥2 prescriptions for at least 30 pills 6 to 12 months posthospitalization) by opioid exposure during the hospitalization. Among the 2971 patients in the study, 64% received opioids during their hospitalization, and 28% were discharged with opioids. A total of 3% of patients had long-term use with a higher pain score associated with greater odds of long-term use.
AHRQ-funded; HS026215.
Citation: Keenan KE, Rothberg MB, Herzig SJ .
Association between opioids prescribed to medical inpatients with pain and long-term opioid use.
South Med J 2021 Oct;114(10):623-29. doi: 10.14423/smj.0000000000001307..
Keywords: Opioids, Hospitalization, Pain, Substance Abuse, Medication
Stevens JP, Dechen T, Schwartzstein R
Prevalence of dyspnea among hospitalized patients at the time of admission.
Dyspnea is an uncomfortable and distressing sensation experienced by hospitalized patients. There is no large-scale study of the prevalence and intensity of patient-reported dyspnea at the time of admission to the hospital. In this study the investigators conducted a prospective cohort study among all consecutive hospitalized patients at a single tertiary care center in Boston, MA. The investigators concluded that dyspnea is a common symptom among all hospitalized patients and that routine documentation of dyspnea is feasible in a large tertiary care center.
AHRQ-funded; HS024288.
Citation: Stevens JP, Dechen T, Schwartzstein R .
Prevalence of dyspnea among hospitalized patients at the time of admission.
J Pain Symptom Manage 2018 Jul;56(1):15-22.e2. doi: 10.1016/j.jpainsymman.2018.02.013..
Keywords: Emergency Department, Hospitalization, Pain
Kannampallil T, Galanter WL, Falck S
Characterizing the pain score trajectories of hospitalized adult medical and surgical patients: a retrospective cohort study.
The authors described a 1-year, retrospective, observational study to characterize pain trajectories of hospitalized adults during the first 48 hours after admission at an urban academic medical center. They found that trajectories showed differences based on race, gender, service, and initial pain score, with patients presumed to have dissimilar pain experiences having markedly different pain trajectories. Pain reduction 48 hours after admission was approximately 50% of the initial pain, while most patients' pain failed to fully resolve.
AHRQ-funded; HS021093.
Citation: Kannampallil T, Galanter WL, Falck S .
Characterizing the pain score trajectories of hospitalized adult medical and surgical patients: a retrospective cohort study.
Pain 2016 Dec;157(12):2739-46. doi: 10.1097/j.pain.0000000000000693.
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Keywords: Diagnostic Safety and Quality, Hospitalization, Pain
Ragsdale L, Zhong W, Morrison W
Pediatric exposure to opioid and sedation medications during terminal hospitalizations in the United States, 2007-2011.
The researchers conducted a retrospective study in which they examined the prescribing patterns of opioid and sedation medications among 37,459 children who died in 430 hospitals in the US 2007-2011. Their study reveals an overall high prevalence of exposure to opioid and sedation medications among pediatric terminal hospitalizations, yet with slightly less than one-half of patients receiving both opioids and sedatives daily near the end of life.
AHRQ-funded; HS018425.
Citation: Ragsdale L, Zhong W, Morrison W .
Pediatric exposure to opioid and sedation medications during terminal hospitalizations in the United States, 2007-2011.
J Pediatr 2015 Mar;166(3):587-93.e1. doi: 10.1016/j.jpeds.2014.10.017..
Keywords: Children/Adolescents, Hospitalization, Medication, Opioids, Pain, Palliative Care