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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 4 of 4 Research Studies DisplayedFan Y, Adam TJ, McEwan R
Detecting signals of interactions between warfarin and dietary supplements in electronic health records.
This study detected signals of interactions between warfarin and seven dietary supplements, viz., alfalfa, garlic, ginger, ginkgo, ginseng, St. John's Wort, and Vitamin E by analyzing structured clinical data and unstructured clinical notes from the University of Minnesota Clinical Data Repository. There was a statistically significant association of warfarin concurrently used with supplements which can potentially increase the risk of adverse events, such as gastrointestinal bleeding.
AHRQ-funded; HS022085.
Citation: Fan Y, Adam TJ, McEwan R .
Detecting signals of interactions between warfarin and dietary supplements in electronic health records.
Stud Health Technol Inform 2017;245:370-74.
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Keywords: Adverse Drug Events (ADE), Blood Thinners, Electronic Health Records (EHRs), Medication, Health Information Technology (HIT)
Furukawa MF, Spector WD, Rhona Limcangco M
AHRQ Author: Furukawa MF, Spector WD, Encinosa WE
Meaningful use of health information technology and declines in in-hospital adverse drug events.
Hospital adoption of electronic health records with Meaningful Use (MU) capabilities expected to improve medication safety has grown rapidly. This study has found that MU capabilities and interoperability were associated with lower occurrence of adverse drug events (ADEs), but the effects did not vary by experience with MU. About one-fifth of the decline in ADEs from 2010 to 2013 was attributable to MU capabilities.
AHRQ-authored.
Citation: Furukawa MF, Spector WD, Rhona Limcangco M .
Meaningful use of health information technology and declines in in-hospital adverse drug events.
J Am Med Inform Assoc 2017 Jul 1;24(4):729-36. doi: 10.1093/jamia/ocw183.
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Keywords: Health Information Technology (HIT), Electronic Health Records (EHRs), Adverse Drug Events (ADE), Patient Safety, Hospitals
Banerji A, Blumenthal KG, Lai KH
Epidemiology of ACE inhibitor angioedema utilizing a large electronic health record.
The objective of this study was to identify the incidence of and risk factors for angioedema caused by angiotensin-converting enzyme inhibitors (ACEIs) using a large integrated electronic health record (EHR). It concluded that the incidence of ACEI angioedema within a large EHR is consistent with large clinical trial data. A history of nonsteroidal anti-inflammatory drug allergy was identified as a risk factor for patients with ACEI angioedema.
AHRQ-funded; HS022728.
Citation: Banerji A, Blumenthal KG, Lai KH .
Epidemiology of ACE inhibitor angioedema utilizing a large electronic health record.
J Allergy Clin Immunol Pract 2017 May - Jun;5(3):744-49. doi: 10.1016/j.jaip.2017.02.018.
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Keywords: Electronic Health Records (EHRs), Medication, Risk, Health Information Technology (HIT), Adverse Drug Events (ADE)
Horsky J, Aarts J, Verheul L
Clinical reasoning in the context of active decision support during medication prescribing.
The purpose of this study was to describe and analyze reasoning patterns of clinicians responding to drug-drug interaction alerts in order to understand the role of patient-specific information in the decision-making process about the risks and benefits of medication therapy. The investigators found that declining an alert suggestion was preceded by sometimes brief but often complex reasoning, prioritizing different aspects of care quality and safety, especially when the perceived risk was higher.
AHRQ-funded; HS021094.
Citation: Horsky J, Aarts J, Verheul L .
Clinical reasoning in the context of active decision support during medication prescribing.
Int J Med Inform 2017 Jan;97:1-11. doi: 10.1016/j.ijmedinf.2016.09.004..
Keywords: Adverse Drug Events (ADE), Adverse Events, Clinical Decision Support (CDS), Shared Decision Making, Electronic Health Records (EHRs), Health Information Technology (HIT), Medical Errors, Medication, Patient Safety