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AHRQ Research Studies Date
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- Children/Adolescents (1)
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- (-) Digestive Disease and Health (6)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 6 of 6 Research Studies DisplayedWang M, Auerbach A, Oreper SM
Leveraging a new ICD-10 diagnosis code to characterize hospitalized patients with primary sclerosing cholangitis.
Primary sclerosing cholangitis (PSC) is a progressive cholestatic liver disease, frequently leading to cirrhosis requiring liver transplantation. PSC is typically affects young White males, but with changing demographics of the U.S. population it is not known if demographics of patients with PSC has also changed. Previous research into PSC has been limited by poor validity of diagnostic codes; an International Classification of Diseases (ICD) code was previously utilized to identify several different cholangitic diseases, making accurate identification of PSC patients in large sets of administrative data problematic. A new, PSC-specific ICD-10 code was introduced in 2018 to more accurately identify PSC patients in administrative datasets. The purpose of this study was to leverage the new ICD-10 code in a current cohort of hospitalized PSC patients to describe this population’s demographics and associate them with clinical characteristics and hospitalization outcomes. The study found there are differences in racial/ethnic and gender distribution by age using the new ICD-10 code. The researchers concluded that as use of this code increases over time, future studies should examine reasons for the differences and implications for inpatient/outpatient PSC management. Additional validation of the ICD-10 code is needed to leverage administrative data to further examine PSC demographics, identify disparities, and optimize management and outcomes among all PSC patients.
AHRQ-funded; HS027369.
Citation: Wang M, Auerbach A, Oreper SM .
Leveraging a new ICD-10 diagnosis code to characterize hospitalized patients with primary sclerosing cholangitis.
Clin Gastroenterol Hepatol 2023 Sep; 21(10):2692-94. doi: 10.1016/j.cgh.2022.09.001..
Keywords: Digestive Disease and Health
Brajcich BC, Johnson JK, Holl JL
Evaluation of emergency department treat-and-release encounters after major gastrointestinal surgery.
The purpose of this study was to assess the incidence of, reasons for, and predictors of emergency department treat-and-release encounters after gastrointestinal cancer operations. The researchers identified patients who underwent elective colorectal, esophageal, gastric, hepatobiliary, pancreatic, or small intestinal operations for cancer from the 2015-2017 Healthcare Cost and Utilization Project State Inpatient and State Emergency Department Databases for New York, Maryland, and Florida. The study found that among 51,527 patients at 406 hospitals, 7.9% had an ED treat-and-release encounter, and 10.8% had an ED encounter with readmission. In total, 40.7% of ED encounters were treat-and-release encounters. 12% of ED treat-and-release encounters were for pain, 11.7% for device/ostomy complaints, and 11.4% were for wound complaints (11.4%). ED treat-and-release encounters predictors included non-Hispanic Black race/ethnicity and Medicare or Medicaid coverage.
AHRQ-funded; HS026385.
Citation: Brajcich BC, Johnson JK, Holl JL .
Evaluation of emergency department treat-and-release encounters after major gastrointestinal surgery.
J Surg Oncol 2023 Aug; 128(2):402-08. doi: 10.1002/jso.27292..
Keywords: Emergency Department, Digestive Disease and Health, Surgery, Hospital Readmissions
Herb J, Rodriguez-Ormaza N, Cunningham C
Gastrostomy tube outcomes among surgical and non-surgical services: a retrospective review.
The purpose of this retrospective analysis study was to evaluate variations in baseline characteristics, complications, and mortality in patients receiving a gastrostomy tube (GT) by surgical or non-surgical services. The researchers assessed adult patients who underwent GT placement from 2014 to 2017 at a single institution. The study found that of the 1,339 adults who underwent GT placement, surgical and non-surgical services performed 45 percent and 55 percent of procedures, respectively. Gastrostomy tube-related complications were similar with 29.6% surgical vs 28.8% non-surgical. The thirty-day mortality rate of 23.7 percent among non-surgical services than the 16.5 percent rate for surgical services.
AHRQ-funded; HS000032.
Citation: Herb J, Rodriguez-Ormaza N, Cunningham C .
Gastrostomy tube outcomes among surgical and non-surgical services: a retrospective review.
Am Surg 2023 Apr; 89(4):813-20. doi: 10.1177/00031348211047173..
Keywords: Surgery, Digestive Disease and Health, Outcomes
Canvasser J, Patel RM, Pryor E
Long-term outcomes and life-impacts of necrotizing enterocolitis: a survey of survivors and parents.
Necrotizing enterocolitis (NEC) is a severe gastrointestinal condition predominantly afflicting preterm infants. Despite its association with unfavorable outcomes within the first two years of life, there is a scarcity of research examining the long-term consequences and life quality in children beyond this age. The purpose of the study was to carry out a survey to assess the enduring repercussions of NEC on physical and psychological well-being, social interactions, and overall life satisfaction as reported by adult survivors and parents of children who overcame NEC. The study found that both survivors and parents of children who have endured NEC encounter persistent challenges affecting their physical and emotional health, social encounters, and overall life contentment.
AHRQ-funded; HS026383
Citation: Canvasser J, Patel RM, Pryor E .
Long-term outcomes and life-impacts of necrotizing enterocolitis: a survey of survivors and parents.
Semin Perinatol 2023 Feb;47(1):151696. doi: 10.1016/j.semperi.2022.151696.
Keywords: Newborns/Infants, Children/Adolescents, Digestive Disease and Health, Outcomes, Quality of Life
Zisman-Ilani Y, Thompson KD, Siegel LS
Crohn's disease shared decision making intervention leads to more patients choosing combination therapy: a cluster randomised controlled trial.
The purpose of this multi-site cluster randomised controlled trial was to test the impact of standard Crohn's disease care and compare with the impact of shared decision making (SDM) on the provider’s choice of therapy, quality of decisions, and provider trust. A total of 158 adult patients with Crohn's disease within 15 years of their diagnosis, with no prior Crohn's disease complications, and who were candidates to receive immunomodulators or biologics, from 14 diverse gastroenterology practices in the US, participated in the study. 99 of those participants received the intervention and 59 received standard care. The study found that participants in the intervention group chose combination therapy more frequently, had a significantly lower decisional conflict, and had greater trust in their provider.
AHRQ-funded; HS021747.
Citation: Zisman-Ilani Y, Thompson KD, Siegel LS .
Crohn's disease shared decision making intervention leads to more patients choosing combination therapy: a cluster randomised controlled trial.
Aliment Pharmacol Ther 2023 Jan;57(2):205-14. doi: 10.1111/apt.17286..
Keywords: Digestive Disease and Health, Chronic Conditions, Shared Decision Making, Patient-Centered Healthcare, Clinician-Patient Communication
Nguyen NH, Luo J, Paul P
Effectiveness and safety of biologic therapy in Hispanic vs non-Hispanic patients with inflammatory bowel diseases: a CA-IBD cohort study.
Researchers compared risk of hospitalization, surgery, and serious infection in Hispanic versus non-Hispanic adult patients with inflammatory bowel diseases (IBDs) who were new recipients of biologic therapy. Their findings indicate that Hispanic patients experienced higher hospitalization, surgery, and serious infection rates. The researchers concluded that future studies should investigate the biological, social, and environmental drivers of these differences.
AHRQ-funded; HS019913.
Citation: Nguyen NH, Luo J, Paul P .
Effectiveness and safety of biologic therapy in Hispanic vs non-Hispanic patients with inflammatory bowel diseases: a CA-IBD cohort study.
Clin Gastroenterol Hepatol 2023 Jan;21(1):173-81.e5. doi: 10.1016/j.cgh.2022.05.008..
Keywords: Digestive Disease and Health, Racial and Ethnic Minorities, Treatments