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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 6 of 6 Research Studies DisplayedBachhuber MA, McGinty EE, Kennedy-Hendricks A
Messaging to increase public support for naloxone distribution policies in the United States: results from a randomized survey experiment.
The investigators conducted a web-based survey (GfK Knowledge Panel) about barriers to public support for naloxone distribution. They concluded that public support for naloxone distribution can be improved through education and sympathetic portrayals of the population who stands to benefit from these policies.
AHRQ-funded; HS000029.
Citation: Bachhuber MA, McGinty EE, Kennedy-Hendricks A .
Messaging to increase public support for naloxone distribution policies in the United States: results from a randomized survey experiment.
PLoS One 2015 Jul;10(7):e0130050. doi: 10.1371/journal.pone.0130050.
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Keywords: Medication, Opioids, Policy, Substance Abuse
Smith RJ, Kilaru AS, Perrone J
How, why, and for whom do emergency medicine providers use prescription drug monitoring programs?
The authors examined how emergency physicians use Prescription Drug Monitoring Programs (PDMPs), for which patients, and for what reasons. They found that providers use the information in PDMPs to alter clinical decisions and guide opioid prescribing patterns. Physicians used the databases additionally for improving their ability to facilitate discussions on addiction and for providing patient education. The authors recommended minimizing administrative barriers to PDMP access and suggested that alternative PDMP uses be further studied to determine their appropriateness and potentially expand their role in clinical practice.
AHRQ-funded; HS021956.
Citation: Smith RJ, Kilaru AS, Perrone J .
How, why, and for whom do emergency medicine providers use prescription drug monitoring programs?
Pain Med 2015 Jun;16(6):1122-31. doi: 10.1111/pme.12700.
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Keywords: Shared Decision Making, Emergency Medical Services (EMS), Medication, Practice Patterns, Substance Abuse
Westover AN, Nakonezny PA, Barlow CE
Exercise outcomes in prevalent users of stimulant medications.
This study compared prevalent stimulant medication users to matched nonusers undergoing a maximal treadmill test for differences in peak systolic blood pressure, average rise in SBP during exercise, peak heart rate (HR), and aerobic exercise capacity. It found that stimulant use was associated with a decreased peak HR as well as an increased risk of chronotropic incompetence.
AHRQ-funded; HS022418.
Citation: Westover AN, Nakonezny PA, Barlow CE .
Exercise outcomes in prevalent users of stimulant medications.
J Psychiatr Res 2015 May;64:32-9. doi: 10.1016/j.jpsychires.2015.03.011.
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Keywords: Medication, Substance Abuse, Patient-Centered Outcomes Research
Hwang CS, Chang HY, Alexander GC
Impact of abuse-deterrent OxyContin on prescription opioid utilization.
The researchers quantified the degree to which the August 2010 reformulation of abuse-deterrent OxyContin affected its use, as well as the use of alternative extended-release and immediate-release opioids. They found that the market debut of abuse-deterrent OxyContin was associated with declines in its use after accounting for the simultaneous contraction of the generic extended-release oxycodone market.
AHRQ-funded; HS018960.
Citation: Hwang CS, Chang HY, Alexander GC .
Impact of abuse-deterrent OxyContin on prescription opioid utilization.
Pharmacoepidemiol Drug Saf 2015 Feb;24(2):197-204. doi: 10.1002/pds.3723.
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Keywords: Medication, Opioids, Prevention, Substance Abuse
Jackson H, Mandell K, Johnson K
Cost-effectiveness of injectable extended-release naltrexone compared with methadone maintenance and buprenorphine maintenance treatment for opioid dependence.
The authors estimated the cost-effectiveness of injectable extended-release naltrexone (XR-NTX) compared with methadone maintenance and buprenorphine maintenance treatment for adult males enrolled in treatment for opioid dependence in the United States from the perspective of state-level addiction treatment payers. They found that XR-NTX is a cost-effective medication for treating opioid dependence if state addiction treatment payers are willing to pay at least $72 per opioid-free day.
AHRQ-funded; HS000083.
Citation: Jackson H, Mandell K, Johnson K .
Cost-effectiveness of injectable extended-release naltrexone compared with methadone maintenance and buprenorphine maintenance treatment for opioid dependence.
Subst Abus 2015;36(2):226-31. doi: 10.1080/08897077.2015.1010031.
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Keywords: Healthcare Costs, Medication, Opioids, Substance Abuse, Treatments
Turner L, Kruszewski SP, Alexander GC
Trends in the use of buprenorphine by office-based physicians in the United States, 2003-2013.
This study used descriptive statistics to examine trends in buprenorphine utilization from 2003 to 2013. The use of buprenorphine products to treat opioid dependence has increased significantly and has shifted to greater use by primary care physicians, indicating a rapidly changing face of opioid maintenance therapy in the United States.
AHRQ-funded; HS018960.
Citation: Turner L, Kruszewski SP, Alexander GC .
Trends in the use of buprenorphine by office-based physicians in the United States, 2003-2013.
Am J Addict 2015 Jan;24(1):24-9. doi: 10.1111/ajad.12174..
Keywords: Healthcare Utilization, Medication, Opioids, Primary Care, Substance Abuse