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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedKrishnan S, Karg PE, Boninger ML
Early detection of pressure ulcer development following traumatic spinal cord injury using inflammatory mediators.
The authors aimed to identify changes in concentrations of inflammatory mediators in plasma and urine after traumatic spinal cord injury and before the occurrence of a first pressure ulcer. They found that an increase in concentration of the chemokine interferon-γ-induced protein in plasma and a decrease in concentration of the cytokine interferon-α in urine were observed before occurrence of a first pressure ulcer compared with matched controls. They concluded that inflammatory mediators should be explored as possible biomarkers for identifying individuals at risk for pressure ulcer formation.
AHRQ-funded; HS022134.
Citation: Krishnan S, Karg PE, Boninger ML .
Early detection of pressure ulcer development following traumatic spinal cord injury using inflammatory mediators.
Arch Phys Med Rehabil 2016 Oct;97(10):1656-62. doi: 10.1016/j.apmr.2016.01.003.
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Keywords: Pressure Ulcers, Healthcare-Associated Infections (HAIs), Injuries and Wounds