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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
151 to 175 of 175 Research Studies DisplayedKinasz K, Accurso EC, Kass AE
Does sex matter in the clinical presentation of eating disorders in youth?
The authors compared demographic and clinical characteristics of child and adolescent males and females who presented for eating disorder treatment. They found that males presented at a significantly younger age and were more likely to be nonwhite, while females showed more severe pathology across the Eating Disorder Examination subscales. They suggested further exploration into why the sexes present differently.
AHRQ-funded; HS000078.
Citation: Kinasz K, Accurso EC, Kass AE .
Does sex matter in the clinical presentation of eating disorders in youth?
J Adolesc Health 2016 Apr;58(4):410-6. doi: 10.1016/j.jadohealth.2015.11.005.
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Keywords: Children/Adolescents, Behavioral Health, Nutrition, Sex Factors
O'Connor BC, Lewandowski RE, Rodriguez S
Usual care for adolescent depression from symptom identification through treatment initiation.
The researchers sought to determine rates of appropriate follow-up care for adolescents with newly identified depression symptoms in 3 large health systems. They concluded that most adolescents with newly identified depression symptoms received some treatment, usually including psychotherapy, within the first 3 months after identification. However, follow-up care was low and substantial variation existed between sites.
AHRQ-funded; HS020503.
Citation: O'Connor BC, Lewandowski RE, Rodriguez S .
Usual care for adolescent depression from symptom identification through treatment initiation.
JAMA Pediatr 2016 Apr;170(4):373-80. doi: 10.1001/jamapediatrics.2015.4158.
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Keywords: Medication, Children/Adolescents, Depression, Behavioral Health
Forman-Hoffman V, McClure E, McKeeman J
Screening for major depressive disorder in children and adolescents: a systematic review for the U.S. Preventive Services Task Force.
This report updates the 2009 U.S. Preventive Services Task Force (USPSTF) systematic review on screening for and treatment of Major depressive disorder (MDD) in children and adolescents in primary care settings. No evidence was found of a direct link between screening children and adolescents for MDD in primary care or similar settings and depression or other health-related outcomes. Evidence showed that some screening tools are accurate.
AHRQ-funded; 290201200015.
Citation: Forman-Hoffman V, McClure E, McKeeman J .
Screening for major depressive disorder in children and adolescents: a systematic review for the U.S. Preventive Services Task Force.
Ann Intern Med 2016 Mar 1;164(5):342-9. doi: 10.7326/m15-2259.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Depression, Behavioral Health, Children/Adolescents
Finnerty M, Neese-Todd S, Pritam R
Access to psychosocial services prior to starting antipsychotic treatment among Medicaid-insured youth.
The researchers sought to examine rates and predictors of receiving a psychosocial service before initiating antipsychotic treatment among young people in the Medicaid program. They found that less than one-half of youth received a psychosocial service before initiating antipsychotic treatment, and youth diagnosed with stress disorders were significantly more likely than those diagnosed with psychotic or bipolar disorders to have received a psychosocial service before starting an antipsychotic. They concluded that this service pattern highlights a critical gap in access to psychosocial services.
AHRQ-funded; HS019937; HS020503; HS021112.
Citation: Finnerty M, Neese-Todd S, Pritam R .
Access to psychosocial services prior to starting antipsychotic treatment among Medicaid-insured youth.
J Am Acad Child Adolesc Psychiatry 2016 Jan;55(1):69-76.e3. doi: 10.1016/j.jaac.2015.09.020.
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Keywords: Access to Care, Children/Adolescents, Medication, Behavioral Health
Hamblin RJ, Lewin AB, Salloum A
Clinical characteristics and predictors of hoarding in children with anxiety disorders.
This investigation was conducted to describe the clinical characteristics of anxious children with significant hoarding behavior and to examine the contributions of anxiety, obsessive compulsive, and inattentive and hyperactive/impulsive symptoms in the prediction of hoarding. Its findings suggest a pattern of behavioral and emotional dysregulation for children who hoard and provide further insight into the relationships between anxiety, attention problems, and hoarding.
AHRQ-funded; HS018665.
Citation: Hamblin RJ, Lewin AB, Salloum A .
Clinical characteristics and predictors of hoarding in children with anxiety disorders.
J Anxiety Disord 2015 Dec;36:9-14. doi: 10.1016/j.janxdis.2015.07.006.
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Keywords: Children/Adolescents, Anxiety, Behavioral Health
Brent DA, Brunwasser SM, Hollon SD
Effect of a cognitive-behavioral prevention program on depression 6 years after implementation among at-risk adolescents: a randomized clinical trial.
The objective of this paper is to determine whether a cognitive-behavioral prevention (CBP) program reduced the incidence of depressive episodes, increased depression-free days, and improved developmental competence 6 years after implementation. Over the 75-month follow-up, youths assigned to CBP had a lower incidence of depression; the CBP program's overall significant effect was driven by a lower incidence of depressive episodes during the first 9 months after enrollment.
AHRQ-funded; HS022990.
Citation: Brent DA, Brunwasser SM, Hollon SD .
Effect of a cognitive-behavioral prevention program on depression 6 years after implementation among at-risk adolescents: a randomized clinical trial.
JAMA Psychiatry 2015 Nov;72(11):1110-8. doi: 10.1001/jamapsychiatry.2015.1559.
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Keywords: Behavioral Health, Children/Adolescents, Depression, Patient-Centered Outcomes Research
Epstein RA, Fonnesbeck C, Potter S
Psychosocial interventions for child disruptive behaviors: a meta-analysis.
The researchers conducted a systematic review and meta-analysis to synthesize existing literature on the comparative effectiveness of psychosocial interventions for children and adolescents, 18 years of age with disruptive behavior disorders. It concluded that the 3 intervention categories were more effective than the control conditions. Interventions with a parent component, either alone or in combination with other components, were likely to have the largest effect.
AHRQ-funded; 290201200009I.
Citation: Epstein RA, Fonnesbeck C, Potter S .
Psychosocial interventions for child disruptive behaviors: a meta-analysis.
Pediatrics 2015 Nov;136(5):947-60. doi: 10.1542/peds.2015-2577..
Keywords: Behavioral Health, Children/Adolescents, Comparative Effectiveness, Patient-Centered Outcomes Research
Radovic A, Reynolds K, McCauley HL
Parents' role in adolescent depression care: primary care provider perspectives.
This study aimed to understand how primary care providers (PCPs) perceive barriers to adolescent depression care in order to inform strategies to increase treatment engagement. PCPs perceived that parental unwillingness to accept the depression diagnosis, family dysfunction, and trauma were common barriers. PCPs contrasted this with examples of good family support they believed would enable adolescents to attend follow-up appointments and have a “life coach” at home.
AHRQ-funded; HS022989; HS019486.
Citation: Radovic A, Reynolds K, McCauley HL .
Parents' role in adolescent depression care: primary care provider perspectives.
J Pediatr 2015 Oct;167(4):911-8. doi: 10.1016/j.jpeds.2015.05.049..
Keywords: Caregiving, Children/Adolescents, Depression, Behavioral Health, Primary Care
Storch EA, Salloum A, Johnco C
Phenomenology and clinical correlates of family accommodation in pediatric anxiety disorders.
This study assessed the nature and clinical correlates of family accommodation in pediatric anxiety, as well as validating a mechanistic model. It concluded that family accommodation was associated with increased anxiety severity and externalizing behaviors, having a diagnosis of separation anxiety, and increased functional impairment. Family accommodation partially mediated the relationship between anxiety severity and functional impairment.
AHRQ-funded; HS018665.
Citation: Storch EA, Salloum A, Johnco C .
Phenomenology and clinical correlates of family accommodation in pediatric anxiety disorders.
J Anxiety Disord 2015 Oct;35:75-81. doi: 10.1016/j.janxdis.2015.09.001.
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Keywords: Children/Adolescents, Anxiety, Behavioral Health, Children/Adolescents, Family Health and History
Johnco CJ, Salloum A, De Nadai AS
Incidence, clinical correlates and treatment effect of rage in anxious children.
This study examined the incidence and clinical correlates of rage in children with anxiety disorders. Change in rage during treatment for anxiety was also examined. It found that rage was associated with a more severe clinical profile, including increased anxiety severity, functional impairment, family accommodation and caregiver strain, as well as poorer relationships with parents, siblings, extended family and peers.
AHRQ-funded; HS018665.
Citation: Johnco CJ, Salloum A, De Nadai AS .
Incidence, clinical correlates and treatment effect of rage in anxious children.
Psychiatry Res 2015 Sep 30;229(1-2):63-9. doi: 10.1016/j.psychres.2015.07.071..
Keywords: Anxiety, Behavioral Health, Children/Adolescents, Family Health and History
Johnco CJ, Salloum A, Lewin AB
The impact of comorbidity profiles on clinical and psychosocial functioning in childhood anxiety disorders.
This study compared the profile of children with a primary anxiety disorder without comorbidity to those with different comorbidity profiles in a treatment-seeking sample of 111 children recruited from community mental health settings. It found that anxiety severity and depressive symptomatology did not vary by comorbidity profile. Anxious children without comorbidity had lower levels of aggressive and externalizing behaviors compared to the comorbid ADHD group.
AHRQ-funded; HS018665.
Citation: Johnco CJ, Salloum A, Lewin AB .
The impact of comorbidity profiles on clinical and psychosocial functioning in childhood anxiety disorders.
Psychiatry Res 2015 Sep 30;229(1-2):237-44. doi: 10.1016/j.psychres.2015.07.027..
Keywords: Children/Adolescents, Anxiety, Behavioral Health
Fan T, Rossi C
AHRQ Author: Fan T
Primary care behavioral interventions to reduce illicit drug and nonmedical pharmaceutical use in children.
This case study involves a 16-year-old white female nonsmoker who presents for a sports clearance physical. It poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: Fan T, Rossi C .
Primary care behavioral interventions to reduce illicit drug and nonmedical pharmaceutical use in children.
Am Fam Physician 2015 Jun 15;91(12):865-6.
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Keywords: Children/Adolescents, Primary Care, Behavioral Health, U.S. Preventive Services Task Force (USPSTF), Substance Abuse
Lu CY, Zhang F, Lakoma MD
Asthma treatments and mental health visits after a Food and Drug Administration label change for leukotriene inhibitors.
This study investigated how a label change to include neuropsychiatric adverse events (e.g., depression and suicidality) affected the use of leukotriene inhibitors (LTIs) and other asthma controller medications, mental health visits, and suicide attempts. The label change was associated with abrupt reductions in LTI use among all age groups.
AHRQ-funded; HS019669.
Citation: Lu CY, Zhang F, Lakoma MD .
Asthma treatments and mental health visits after a Food and Drug Administration label change for leukotriene inhibitors.
Clin Ther 2015 Jun;37(6):1280-91. doi: 10.1016/j.clinthera.2015.03.027..
Keywords: Adverse Drug Events (ADE), Asthma, Children/Adolescents, Medication, Behavioral Health
Olfson M, Druss BG, Marcus SC
Trends in mental health care among children and adolescents.
This study examined national trends in the use of outpatient mental health services by children and adolescents, focusing on the severity of mental health impairment. It found that outpatient mental health treatment and psychotropic-medication use in children and adolescents increased in the United States between 1996–1998 and 2010–2012. Youths with less severe or no impairment accounting for most of the absolute increase in service use.
AHRQ-funded; HS021112.
Citation: Olfson M, Druss BG, Marcus SC .
Trends in mental health care among children and adolescents.
N Engl J Med 2015 May 21;372(21):2029-38. doi: 10.1056/NEJMsa1413512..
Keywords: Children/Adolescents, Medical Expenditure Panel Survey (MEPS), Behavioral Health, Ambulatory Care and Surgery
Garfield LD, Brown DS, Allaire BT
Psychotropic drug use among preschool children in the Medicaid program from 36 states.
The researchers examined utilization of the most commonly used psychotropic medications among children aged 4 years and younger. They determined the prevalence of and indications for psychotropic medication among preschool children in Medicaid. Their study found that preschoolers are receiving psychotropic medications despite limited evidence supporting safety or efficacy. Medications for attention-deficit disorder/attention-deficit hyperactivity disorder treatment were most common.
AHRQ-funded; HS020269.
Citation: Garfield LD, Brown DS, Allaire BT .
Psychotropic drug use among preschool children in the Medicaid program from 36 states.
Am J Public Health 2015 Mar;105(3):524-9. doi: 10.2105/ajph.2014.302258..
Keywords: Children/Adolescents, Medication, Medicaid, Behavioral Health
Torio CM, Encinosa WE, Berdahl T
AHRQ Author: Torio CM, Encinosa WE, Berdahl T
Annual report on health care for children and youth in the United States: national estimates of cost, utilization and expenditures for children with mental health conditions.
This study examined national trends in hospital utilization, costs, and expenditures for children with mental health conditions between 2006 and 2011. It found that hospitalizations for all listed mental health conditions increased by nearly 50 percent among children aged 10 to 14 years and by 21 percent for emergency department visits.
AHRQ-authored
Citation: Torio CM, Encinosa WE, Berdahl T .
Annual report on health care for children and youth in the United States: national estimates of cost, utilization and expenditures for children with mental health conditions.
Acad Pediatr. 2015 Jan-Feb;15(1):19-35. doi: 10.1016/j.acap.2014.07.007..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Medical Expenditure Panel Survey (MEPS), Behavioral Health
Bauer NS, Anand V, Carroll AE
Secondhand smoke exposure, parental depressive symptoms and preschool behavioral outcomes.
In order to learn about the association of second-hand smoke (SHS) exposure to behavioral conditions among preschoolers, the researchers looked at billing and pharmacy claims and medical encounter level data. They found that SHS is associated with behavioral conditions such as attention deficit-hyperactivity disorder and disruptive behavior disorder.
AHRQ-funded; HS018453; HS017939
Citation: Bauer NS, Anand V, Carroll AE .
Secondhand smoke exposure, parental depressive symptoms and preschool behavioral outcomes.
J Pediatr Nurs. 2015 Jan-Feb;30(1):227-35. doi: 10.1016/j.pedn.2014.06.004..
Keywords: Children/Adolescents, Behavioral Health, Tobacco Use
Christian RB, Gaynes BN, Saavedra LM
Use of antipsychotic medications in pediatric and young adult populations: future research needs.
This article describes and prioritizes future research needs regarding antipsychotic treatment in youth, focusing on within-class and between-class drug comparisons with regard to key population subgroups, efficacy and effectiveness outcomes, and adverse event outcomes. Future research needs are delineated in detail as well as study designs that could be used to address them.
AHRQ-funded; 290200710056I.
Citation: Christian RB, Gaynes BN, Saavedra LM .
Use of antipsychotic medications in pediatric and young adult populations: future research needs.
J Psychiatr Pract 2015 Jan;21(1):26-36. doi: 10.1097/01.pra.0000460619.10429.4c..
Keywords: Medication, Children/Adolescents, Behavioral Health, Comparative Effectiveness, Patient-Centered Outcomes Research
Raghavan R, Brown DS, Allaire BT
Medicaid expenditures on psychotropic medications for maltreated children: a study of 36 States.
The authors aimed to quantify the magnitude of Medicaid expenditures incurred in the purchase of psychotropic drugs for children with histories of abuse or neglect. They concluded that Medicaid agencies should focus their cost containment strategies on antidepressants and antimanic drugs, consider expanding primary care case management arrangements, and expand use of instruments such as the Child Behavior Checklist to identify and treat high-need children.
AHRQ-funded; HS020269.
Citation: Raghavan R, Brown DS, Allaire BT .
Medicaid expenditures on psychotropic medications for maltreated children: a study of 36 States.
Psychiatr Serv 2014 Dec;65(12):1445-51. doi: 10.1176/appi.ps.201400028.
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Keywords: Children/Adolescents, Healthcare Costs, Medicaid, Medication, Behavioral Health
Saloner B, Matone M, Kreider AR
Second-generation antipsychotic use among stimulant-using children, by organization of Medicaid mental health.
The authors compared differences in second-generation antipsychotic utilization among Medicaid-enrolled children across fee-for-service, integrated managed care, and managed behavioral health carve-out organizational structures. They found that carve-outs, versus other arrangements, were associated with lower second-generation antipsychotic use.
AHRQ-funded; HS020269; HS018550.
Citation: Saloner B, Matone M, Kreider AR .
Second-generation antipsychotic use among stimulant-using children, by organization of Medicaid mental health.
Psychiatr Serv 2014 Dec;65(12):1458-64. doi: 10.1176/appi.ps.201300574.
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Keywords: Children/Adolescents, Healthcare Utilization, Medicaid, Medication, Behavioral Health
Vanderwerker L, Akincigil A, Olfson M
Foster care, externalizing disorders, and antipsychotic use among Medicaid-enrolled youths.
The researchers investigated the extent to which clinical diagnoses of externalizing disorders explain higher rates of antipsychotic use by foster care youths. They found that foster care youths had higher rates of externalizing disorders than the comparison group and greater antipsychotic use. Foster care remained a significant predictor of antipsychotic use after control for demographic and diagnostic covariates.
AHRQ-funded; HS017918; HS019937; HS021112.
Citation: Vanderwerker L, Akincigil A, Olfson M .
Foster care, externalizing disorders, and antipsychotic use among Medicaid-enrolled youths.
Psychiatr Serv 2014 Oct;65(10):1281-4. doi: 10.1176/appi.ps.201300455.
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Keywords: Children/Adolescents, Medication, Medicaid, Vulnerable Populations, Behavioral Health
Bardach NS, Coker TR, Zima BT
Common and costly hospitalizations for pediatric mental health disorders.
The objectives of this study were to describe pediatric mental health hospitalizations at general medical facilities admitting children nationally; to assess which pediatric mental health diagnoses are frequent and costly at these hospitals; and to examine whether the most frequent diagnoses are similar to those at free-standing children's hospitals. The investigators identified the child mental health inpatient diagnoses with the highest frequency and highest costs as depression, bipolar disorder, and psychosis, with substance abuse an important comorbid diagnosis.
AHRQ-funded; HS020506.
Citation: Bardach NS, Coker TR, Zima BT .
Common and costly hospitalizations for pediatric mental health disorders.
Pediatrics 2014 Apr;133(4):602-9. doi: 10.1542/peds.2013-3165..
Keywords: Children/Adolescents, Healthcare Costs, Hospitalization, Behavioral Health
Bardach NS, Coker TR, Zima BT
Common and costly hospitalizations for pediatric mental health disorders.
The objectives of this study were to describe pediatric mental health hospitalizations at general medical facilities admitting children nationally; to assess which pediatric mental health diagnoses are frequent and costly at these hospitals; and to examine whether the most frequent diagnoses are similar to those at free-standing children's hospitals. The investigators identified the child mental health inpatient diagnoses with the highest frequency and highest costs as depression, bipolar disorder, and psychosis, with substance abuse an important comorbid diagnosis.
AHRQ-funded; HS020506.
Citation: Bardach NS, Coker TR, Zima BT .
Common and costly hospitalizations for pediatric mental health disorders.
Pediatrics 2014 Apr;133(4):602-9. doi: 10.1542/peds.2013-3165..
Keywords: Children/Adolescents, Healthcare Costs, Hospitalization, Behavioral Health
Gilbert AL, Bauer NS, Carroll AE
Child exposure to parental violence and psychological distress associated with delayed milestones.
The researchers examined the association between parental report of intimate partner violence (IPV) and parental psychological distress (PPD) with child attainment of developmental milestones. They found that parental report of both IPV and PPD during the first 72 months of a child’s life is significantly associated with developmental milestone failure across all 4 developmental domains and within the domains of language, personal-social, and gross motor development.
AHRQ-funded; HS017939; HS018453.
Citation: Gilbert AL, Bauer NS, Carroll AE .
Child exposure to parental violence and psychological distress associated with delayed milestones.
Pediatrics 2013 Dec;132(6):e1577-83. doi: 10.1542/peds.2013-1020..
Keywords: Children/Adolescents, Domestic Violence, Family Health and History, Depression, Anxiety, Behavioral Health
Bobo WV, Cooper WO, Stein CM
Antipsychotics and the risk of type 2 diabetes mellitus in children and youth.
This study found that in a group of 25, 834 Medicaid-enrolled children and youth who had recently initiated use of either an antipsychotic or a control psychotropic drug, antipsychotic users had a risk of a newly diagnosed type 2 diabetes 3 times greater than the propensity-score matched controls. This group was confined to those who had not been diagnosed with conditions for which antipsychotics were the only recognized pharmacotherapy.
AHRQ-funded; HS0116974
Citation: Bobo WV, Cooper WO, Stein CM .
Antipsychotics and the risk of type 2 diabetes mellitus in children and youth.
JAMA Psychiatry. 2013 Oct;70(10):1067-75. doi: 10.1001/jamapsychiatry.2013.2053..
Keywords: Children/Adolescents, Behavioral Health, Diabetes, Medication, Medicaid