National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
526 to 549 of 549 Research Studies DisplayedOlsen MA, Nickel KB, Margenthaler JA
Increased risk of surgical site infection among breast-conserving surgery re-excisions.
The aim of this study was to determine the risk of surgical site infection (SSI) after primary breast-conserving surgery (BCS) versus re-excision among women with carcinoma in situ or invasive breast cancer. It found that the risk of SSI after re-excision remained significantly higher after accounting for multiple procedures within a woman.
AHRQ-funded; HS019713.
Citation: Olsen MA, Nickel KB, Margenthaler JA .
Increased risk of surgical site infection among breast-conserving surgery re-excisions.
Ann Surg Oncol 2015;22(6):2003-9. doi: 10.1245/s10434-014-4200-x..
Keywords: Surgery, Risk, Cancer: Breast Cancer, Cancer, Healthcare-Associated Infections (HAIs), Injuries and Wounds, Adverse Events, Patient Safety, Women
Atkins EV, Sambamoorthi U, Bhattacharya R
Variations of depression treatment among women with hypertension.
This study examined depression treatment patterns among women with hypertension utilizing the Medical Expenditures Panel Survey (MEPS), a nationally representative survey of families and individuals, their medical providers, and employers across the United States. It found that 23.9 percent had no depression treatment, 56.8 percent had antidepressant use only, and 19.3 percent had psychotherapy with or without antidepressants.
AHRQ-funded; HS018622.
Citation: Atkins EV, Sambamoorthi U, Bhattacharya R .
Variations of depression treatment among women with hypertension.
Health Care Women Int 2015;36(6):730-50. doi: 10.1080/07399332.2015.1005303..
Keywords: Medical Expenditure Panel Survey (MEPS), Depression, Blood Pressure, Women, Behavioral Health
Vyas A, Madhavan S, Sambamoorthi U
Association between persistence with mammography screening and stage at diagnosis among elderly women diagnosed with breast cancer.
The objective of this study is to determine the association between persistence with mammography screening and stage at breast cancer (BC) diagnosis among elderly women. It found that, as compared to women who were not persistent with mammography screening, women who were persistent with mammography screening were significantly more likely to be diagnosed at earlier stages of BC.
AHRQ-funded; HS018622.
Citation: Vyas A, Madhavan S, Sambamoorthi U .
Association between persistence with mammography screening and stage at diagnosis among elderly women diagnosed with breast cancer.
Breast Cancer Res Treat 2014 Dec;148(3):645-54. doi: 10.1007/s10549-014-3204-3..
Keywords: Cancer, Cancer: Breast Cancer, Diagnostic Safety and Quality, Elderly, Prevention, Screening, Women
Connor KA, Cheng D, Strobino D
Preconception health promotion among Maryland women.
The objective of this study was to identify factors associated with receipt of preconception care (PCC) health promotion counseling among Maryland women and to assess whether prior birth outcome affects receipt of counseling. PCC receipt in the sample, consistent with analyses of older data, was low at 33 percent for all women and 28 percent for women with a prior live birth.
AHRQ-funded; HS017596.
Citation: Connor KA, Cheng D, Strobino D .
Preconception health promotion among Maryland women.
Matern Child Health J 2014 Dec;18(10):2437-45. doi: 10.1007/s10995-014-1482-3..
Keywords: Health Promotion, Maternal Care, Pregnancy, Women
Diaz OV, Guendelman S, Kuppermann M
Subjective social status and depression symptoms: a prospective study of women with noncancerous pelvic problems.
The investigators sought to examine the effect of community and national subjective social status (SSS) on symptoms of depression in a racially/ethnically diverse sample of adult women with noncancerous uterine conditions. They found that low perceived community social status is predictive of symptoms suggestive of major or other depressive disorder among women with noncancerous uterine conditions.
AHRQ-funded; HS011657.
Citation: Diaz OV, Guendelman S, Kuppermann M .
Subjective social status and depression symptoms: a prospective study of women with noncancerous pelvic problems.
Womens Health Issues 2014 Nov-Dec;24(6):649-55. doi: 10.1016/j.whi.2014.07.003.
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Keywords: Depression, Health Status, Pain, Social Determinants of Health, Women
Dublin S, Johnson KE, Walker RL
Trends in elective labor induction for six United States health plans, 2001-2007.
The authors sought to describe trends in labor induction, including elective induction, from 2001 to 2007 for six U.S. health plans and to examine the validity of induction measures derived from birth certificate and health plan data. They found that induction prevalence rose from 28% in 2001 to 32% in 2005, then declined to 29% in 2007, with the trend being similar for subgroups by parity and gestational age. Elective induction prevalence varied considerably across plans.
AHRQ-funded; HS016955.
Citation: Dublin S, Johnson KE, Walker RL .
Trends in elective labor induction for six United States health plans, 2001-2007.
J Womens Health 2014 Nov;23(11):904-11. doi: 10.1089/jwh.2014.4779.
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Keywords: Centers for Education and Research on Therapeutics (CERTs), Health Insurance, Labor and Delivery, Pregnancy, Women
Jacoby VL, Jacoby A, Learman LA
Use of medical, surgical and complementary treatments among women with fibroids.
This study examined the use of medical management, uterus-preserving surgery, and complementary treatments among women with uterine fibroids. It found that uterus-preserving fibroid surgery is effective, but many symptomatic women can be successfully treated with nonsurgical management, including complementary and alternative therapy.
AHRQ-funded; HS011657; HS07373; HS09478.
Citation: Jacoby VL, Jacoby A, Learman LA .
Use of medical, surgical and complementary treatments among women with fibroids.
Eur J Obstet Gynecol Reprod Biol 2014 Nov;182:220-5. doi: 10.1016/j.ejogrb.2014.09.004..
Keywords: Care Management, Complementary and Alternative Medicine, Medication, Surgery, Treatments, Women
Cea Soriano L, Bateman BT, Garcia Rodriguez LA
Prescription of antihypertensive medications during pregnancy in the UK.
The authors aimed to describe the management of antihypertensive medications in pregnancy by general practitioners in the UK and compare it with current guidelines. Using electronic medical records from The Health Improvement Network database, they found that, in this population of UK pregnant women, prescription patterns of antihypertensive medications were dominated by recommended treatments, although some patients continued on contraindicated drugs throughout pregnancy or switched to preferred agents in a delayed fashion.
AHRQ-funded; HS018533.
Citation: Cea Soriano L, Bateman BT, Garcia Rodriguez LA .
Prescription of antihypertensive medications during pregnancy in the UK.
Pharmacoepidemiol Drug Saf 2014 Oct;23(10):1051-8. doi: 10.1002/pds.3641.
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Keywords: Blood Pressure, Pregnancy, Medication, Women, Practice Patterns
Dood RL, Gracia CR, Sammel MD
Endometrial cancer after endometrial ablation vs medical management of abnormal uterine bleeding.
The authors investigated whether endometrial ablation is associated with increased risk or delayed diagnosis of endometrial cancer compared with medical management of abnormal uterine bleeding. They observed no difference in endometrial cancer rates, nor was there a delay in diagnosis when comparing endometrial ablation vs medical management.
AHRQ-funded; HS021336.
Citation: Dood RL, Gracia CR, Sammel MD .
Endometrial cancer after endometrial ablation vs medical management of abnormal uterine bleeding.
J Minim Invasive Gynecol 2014 Sep-Oct;21(5):744-52. doi: 10.1016/j.jmig.2014.02.012.
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Keywords: Cancer, Comparative Effectiveness, Diagnostic Safety and Quality, Patient-Centered Outcomes Research, Women
Allgood KL, Rauscher GH, Whitman S
Validating self-reported mammography use in vulnerable communities: findings and recommendations.
The researchers examined the potential extent of overreporting of mammography use in low-income African-American and Latina women, and whether self-report inaccuracies might bias estimated associations between patient characteristics and mammography use. They found that although 73% of women self-reported a mammogram in the last 2 years, only 44% of self-reports were documented. Overreporting of mammography use was observed for all ethnic groups studied.
AHRQ-funded; HS018366.
Citation: Allgood KL, Rauscher GH, Whitman S .
Validating self-reported mammography use in vulnerable communities: findings and recommendations.
Cancer Epidemiol Biomarkers Prev 2014 Aug;23(8):1649-58. doi: 10.1158/1055-9965.epi-13-1253.
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Keywords: Healthcare Utilization, Vulnerable Populations, Racial and Ethnic Minorities, Women, Low-Income, Urban Health
Darney BG, Caughey AB
Elective induction of labor symposium: nomenclature, research methodological issues, and outcomes.
This article focuses on key method issues in studies of elective induction of labor. The authors first identify methodological concerns with the existing literature and discuss each in return. They then review existing evidence about the relationship between elective induction and cesarean delivery.
AHRQ-funded; HS017582
Citation: Darney BG, Caughey AB .
Elective induction of labor symposium: nomenclature, research methodological issues, and outcomes.
Clin Obstet Gynecol. 2014 Jun;57(2):343-62. doi: 10.1097/GRF.0000000000000029..
Keywords: Research Methodologies, Outcomes, Labor and Delivery, Women
Wu JM, Matthews CA, Conover MM
Lifetime risk of stress urinary incontinence or pelvic organ prolapse surgery.
Using current, population-based surgical rates from 2007 to 2011, the researchers estimated the lifetime risk of stress urinary incontinence surgery, pelvic organ prolapse surgery or both to be 20 percent by the age of 80.
AHRQ-funded; HS017950.
Citation: Wu JM, Matthews CA, Conover MM .
Lifetime risk of stress urinary incontinence or pelvic organ prolapse surgery.
Obstet Gynecol. 2014 Jun;123(6):1201-6. doi: 10.1097/AOG.0000000000000286..
Keywords: Risk, Surgery, Women
Camelo Castillo W, Boggess K, Stürmer T
Trends in glyburide compared with insulin use for gestational diabetes treatment in the United States, 2000-2011.
The researchers sought to characterize pharmacologic treatment of women with gestational diabetes (GDM) by describing trends in the use of glyburide compared with insulin over the past decade (2000-2011) and identifying predictors of initial choice of pharmacotherapy. They found that glyburide has replaced insulin as the more common pharmacotherapy for GDM among those privately insured.
AHRQ-funded; HS017950
Citation: Camelo Castillo W, Boggess K, Stürmer T .
Trends in glyburide compared with insulin use for gestational diabetes treatment in the United States, 2000-2011.
Obstet Gynecol. 2014 Jun;123(6):1177-84. doi: 10.1097/AOG.0000000000000285..
Keywords: Diabetes, Maternal Care, Medication, Practice Patterns, Pregnancy, Women
Yaghjyan L, Wolin K, Chang SH
Racial disparities in healthy behaviors and cancer screening among breast cancer survivors and women without cancer: National Health Interview Survey 2005.
This study aimed to compare healthy behaviors and cancer screening practices among breast cancer survivors and respondents without cancer separately in Caucasian, African American, and Hispanic women. It found that most differences were suggestive and do not differ by race.
AHRQ-funded; HS022330.
Citation: Yaghjyan L, Wolin K, Chang SH .
Racial disparities in healthy behaviors and cancer screening among breast cancer survivors and women without cancer: National Health Interview Survey 2005.
Cancer Causes Control. 2014 May;25(5):605-14. doi: 10.1007/s10552-014-0365-7..
Keywords: Cancer: Breast Cancer, Cancer, Racial and Ethnic Minorities, Women, Disparities, Screening
Bushnell CD, Reeves MJ, Zhao X
Sex differences in quality of life after ischemic stroke.
This study compared quality of life (QOL) in men and women at 3 and 12 months after stroke, and the change in QOL over time between men and women. It found that women have worse QOL than men up to 12 months after stroke, even after adjusting for important sociodemographic variables and stroke severity.
AHRQ-funded; HS016964.
Citation: Bushnell CD, Reeves MJ, Zhao X .
Sex differences in quality of life after ischemic stroke.
Neurology 2014 Mar 18;82(11):922-31. doi: 10.1212/wnl.0000000000000208..
Keywords: Stroke, Disparities, Women, Social Determinants of Health
Nelson HD, Pappas M, Zakher B
Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: a systematic review to update the U.S. Preventive Services Task Force recommendation.
This systematic review was done in support of the U.S. Preventive Services Task Force (USPSTF) updated recommendation on the benefit and harms of risk assessment, genetic testing, and genetic counseling for BRCA-related cancer in women. A systematic review was done on literature from 2004 to July 30, 2013 from MEDLINE, PsycINFO, the Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Health Technology Assessment, Scopus, and reference lists. Data on the participants, study design, analysis, follow-up, and results was extracted and a second investigator confirmed key data. The studies were rated on study quality and applicability. The analysis found women with high-risk for breast cancer had decreased risk of breast cancer by 85% to 100% by having a mastectomy, and risk of mortality by 81% to 100% compared to women without surgery. There was also a lower risk of breast and ovarian cancer after having salpingo-oopherectomy surgery.
AHRQ-funded; 290200710057
Citation: Nelson HD, Pappas M, Zakher B .
Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: a systematic review to update the U.S. Preventive Services Task Force recommendation.
Ann Intern Med 2014 Feb 18;160(4):255-66. doi: 10.7326/m13-1684..
Keywords: U.S. Preventive Services Task Force (USPSTF), Cancer: Breast Cancer, Cancer: Ovarian Cancer, Cancer, Genetics, Screening, Prevention, Guidelines, Evidence-Based Practice, Women, Risk, Family Health and History
Hendrich A, McCoy CK, Gale J
Ascension health's demonstration of full disclosure protocol for unexpected events during labor and delivery shows promise.
This article presents a case study concerning challenges, including physician resistance, to the establishment of a common full disclosure protocol at five labor and delivery demonstration sites. Twenty-seven months after implementation, the rate of full disclosure had increased by 221 percent. Practitioners saw a number of factors as key catalysts for change including consistent and ongoing leadership by local practitioners and hospitals.
AHRQ-funded; HS019608.
Citation: Hendrich A, McCoy CK, Gale J .
Ascension health's demonstration of full disclosure protocol for unexpected events during labor and delivery shows promise.
Health Aff 2014 Jan;33(1):39-45. doi: 10.1377/hlthaff.2013.1009..
Keywords: Adverse Events, Clinician-Patient Communication, Communication, Labor and Delivery, Medical Errors, Medical Liability, Policy, Pregnancy, Women
Fain K, Alexander GC
Are Food and Drug Administration prescription drug safety plans working? A case study of isotretinoin.
The authors comment on a case study analyzing pharmacy claims in order to examine the impact of the iPledge program (an FDA restricted distribution plan that included electronic registration of patients, physicians, and pharmacists plus monitoring of contraceptive use) on contraceptive use for women of childbearing age taking isotretinoin (Accutane). This drug, used for acute acne, could affect fetal development. The limited effectiveness of the program shows the difficulty of changing patient behavior.
AHRQ-funded; HS0189960
Citation: Fain K, Alexander GC .
Are Food and Drug Administration prescription drug safety plans working? A case study of isotretinoin.
Pharmacoepidemiol Drug Saf. 2013 Dec;22(12):1258-62. doi: 10.1002/pds.3514..
Keywords: Patient Safety, Medication: Safety, Medication, Health Information Technology (HIT), Women
Letourneau AR, Calderwood MS, Huang SS
Harnessing claims to improve detection of surgical site infections following hysterectomy and colorectal surgery.
The researchers conducted retrospective cohort studies at 2 academic medical centers, extending analyses of patients undergoing hysterectomy or colorectal surgery. They concluded that claims-enhanced surveillance can help to identify surgical site infections (SSIs) missed by routine surveillance, identifying nearly twice as many SSIs following hysterectomy and 4 times more SSIs following colorectal surgery.
AHRQ-funded; HS021424.
Citation: Letourneau AR, Calderwood MS, Huang SS .
Harnessing claims to improve detection of surgical site infections following hysterectomy and colorectal surgery.
Infect Control Hosp Epidemiol 2013 Dec;34(12):1321-3. doi: 10.1086/673975..
Keywords: Healthcare-Associated Infections (HAIs), Injuries and Wounds, Surgery, Patient Safety, Adverse Events, Women, Digestive Disease and Health
Suskind AM, Clemens JQ, Dunn RL
Effectiveness of mesh compared with nonmesh sling surgery in Medicare beneficiaries.
This study assessed the effectiveness of mesh compared to nonmesh slings in the surgical treatment of female incontinence. It found that overall rates of complications were similar for patients undergoing either mesh or nonmesh sling procedures. However, patients undergoing the nonmesh procedure were more likely to require a subsequent intervention for bladder outlet obstruction.
AHRQ-funded; HS018726.
Citation: Suskind AM, Clemens JQ, Dunn RL .
Effectiveness of mesh compared with nonmesh sling surgery in Medicare beneficiaries.
Obstet Gynecol. 2013 Sep;122(3):546-52. doi: 10.1097/AOG.0b013e31829e8543..
Keywords: Comparative Effectiveness, Elderly, Patient-Centered Outcomes Research, Surgery, Women, Outcomes, Medicare, Evidence-Based Practice
Matthews CA, Whitehead WE, Townsend MK
Risk factors for urinary, fecal, or dual incontinence in the Nurses' Health Study.
This study estimating the prevalence of urinary incontinence, fecal incontinence, and dual incontinence in a group of 64,396 women aged 62-87 years found that 38 percent had urinary incontinence alone, 4 percent had fecal incontinence alone, and 7 percent had dual incontinence. Dual incontinence was primarily associated with advanced age, decompensating medical conditions, depression, and multiparity.
AHRQ-funded; HS018695.
Citation: Matthews CA, Whitehead WE, Townsend MK .
Risk factors for urinary, fecal, or dual incontinence in the Nurses' Health Study.
Obstet Gynecol. 2013 Sep;122(3):539-45. doi: 10.1097/AOG.0b013e31829efbff..
Keywords: Chronic Conditions, Elderly, Women
Tsui J, Gee GC, Rodriguez HP
Exploring the role of neighborhood socio-demographic factors on HPV vaccine initiation among low-income, ethnic minority girls.
This study of neighborhood factors associated with human papillomavirus (HPV) vaccine uptake, especially among disadvantaged groups, found that initiation rates were highest among girls from the most disadvantaged neighborhoods. However, mother’s awareness of HPV, age, and insurance status were also strong predictors for initiation.
AHRQ-funded; HS020172
Citation: Tsui J, Gee GC, Rodriguez HP .
Exploring the role of neighborhood socio-demographic factors on HPV vaccine initiation among low-income, ethnic minority girls.
J Immigr Minor Health. 2013 Aug;15(4):732-40. doi: 10.1007/s10903-012-9736-x..
Keywords: Vaccination, Children/Adolescents, Women, Health Insurance, Disparities
Jonsson Funk M, Visco AG, Weidner AC
Long-term outcomes of vaginal mesh versus native tissue repair for anterior vaginal wall prolapse.
This study estimated the rate of repeat surgery after vaginal mesh versus native tissue repair for anterior vaginal wall prolapse. The researchers found that the overall risk of any future surgery was higher in the women receiving mesh; however, native tissue and vaginal mesh surgery had similar 5-year risks for recurrent prolapse.
AHRQ-funded; HS017950
Citation: Jonsson Funk M, Visco AG, Weidner AC .
Long-term outcomes of vaginal mesh versus native tissue repair for anterior vaginal wall prolapse.
Int Urogynecol J. 2013 Aug;24(8):1279-85. doi: 10.1007/s00192-013-2043-9..
Keywords: Comparative Effectiveness, Surgery, Women, Outcomes, Risk
Clancy CM, Collins Sharp BA
AHRQ Author: Clancy CM, Collins Sharp BA
Women's health during health care transformation.
This article describes health care transformation as it affects women as a result of the Affordable Care Act of 2010. Topics discussed include USPSTF-recommended preventve services, patient-centered medical homes, access, health disparities, and the Veterans Health Administration healthcare system.
AHRQ-authored.
Citation: Clancy CM, Collins Sharp BA .
Women's health during health care transformation.
J Gen Intern Med 2013 Jul;28 Suppl 2:S500-3. doi: 10.1007/s11606-013-2473-6.
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Keywords: Healthcare Delivery, Policy, Policy, Women