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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 3 of 3 Research Studies DisplayedBergman ZR, Tignanelli CJ, Gould R
Factors associated with mortality in patients with COVID-19 receiving prolonged ventilatory support.
This study examined outcomes for COVID-19 patients who required mechanical ventilation from March 2020 through December 2021 across a system of 11 hospitals. A cohort of 600 patients were included, with in-hospital mortality of 40.3%. Increased age, prolonged ventilation, receiving corticosteroids, and being non-English speaking were associated with mortality. Intubations lasting longer than 21 days had a lower in-hospital mortality of 25.7%.
AHRQ-funded; HS026379.
Citation: Bergman ZR, Tignanelli CJ, Gould R .
Factors associated with mortality in patients with COVID-19 receiving prolonged ventilatory support.
Surg Infect 2022 Dec;23(10):893-901. doi: 10.1089/sur.2022.195..
Keywords: COVID-19, Mortality, Respiratory Conditions
Gershengorn HB, Hu Y, Chen JT
The impact of high-flow nasal cannula use on patient mortality and the availability of mechanical ventilators in COVID-19.
This study looked at the effects of the use of high-flow nasal cannula for COVID-19 patients on mortality and the availability of mechanical ventilators. The authors constructed dynamical simulation models of high-flow nasal cannula and mechanical ventilation use in the United States. There were two outcomes looked for: 1) cumulative number of deaths; and 2) days without available ventilators. The strategy resulted in an estimated number of 10,000-40,000 fewer deaths than if high-flow nasal cannula were not available. This strategy also led up to 25 fewer days without available ventilators.
AHRQ-funded; HS026188.
Citation: Gershengorn HB, Hu Y, Chen JT .
The impact of high-flow nasal cannula use on patient mortality and the availability of mechanical ventilators in COVID-19.
Ann Am Thorac Soc 2021 Apr;18(4):623-31. doi: 10.1513/AnnalsATS.202007-803OC..
Keywords: COVID-19, Respiratory Conditions, Mortality, Critical Care
Donnelly JP, Wang XQ, Iwashyna TJ
Readmission and death after initial hospital discharge among patients with COVID-19 in a large multihospital system.
This study describes reasons for readmission, use of intensive care unit (ICU) interventions during readmission, and proportions of death after initial hospital discharge of COVID-19 patients from US Veterans Affairs (VA) hospitals March-June 2020.
AHRQ-funded; HS026725.
Citation: Donnelly JP, Wang XQ, Iwashyna TJ .
Readmission and death after initial hospital discharge among patients with COVID-19 in a large multihospital system.
JAMA 2021 Jan 19;325(3):304-06. doi: 10.1001/jama.2020.21465.
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Keywords: Respiratory Conditions, COVID-19, Hospital Readmissions, Hospital Discharge, Mortality, Outcomes