National Healthcare Quality and Disparities Report
Latest available findings on quality of and access to health care
Data
- Data Infographics
- Data Visualizations
- Data Tools
- Data Innovations
- All-Payer Claims Database
- Healthcare Cost and Utilization Project (HCUP)
- Medical Expenditure Panel Survey (MEPS)
- AHRQ Quality Indicator Tools for Data Analytics
- State Snapshots
- United States Health Information Knowledgebase (USHIK)
- Data Sources Available from AHRQ
Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Events (2)
- Blood Clots (1)
- (-) Central Line-Associated Bloodstream Infections (CLABSI) (10)
- Evidence-Based Practice (1)
- Guidelines (1)
- Healthcare-Associated Infections (HAIs) (10)
- Home Healthcare (4)
- Hospitalization (1)
- Hospitals (3)
- Infectious Diseases (2)
- Inpatient Care (1)
- Kidney Disease and Health (1)
- Nursing (1)
- Patient Safety (6)
- Prevention (3)
- Provider (1)
- Provider: Nurse (1)
- Risk (2)
- Sepsis (1)
- Teams (1)
AHRQ Research Studies
Sign up: AHRQ Research Studies Email updates
Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 10 of 10 Research Studies DisplayedKeller SC, Hannum SM, Weems K
Implementing and validating a home-infusion central-line-associated bloodstream infection surveillance definition.
Researchers tested the validity of a home-infusion central-line-associated bloodstream infection (CLABSI) surveillance definition and the feasibility and acceptability of its implementation. Their study was conducted in large home-infusion agencies in a CLABSI prevention collaborative in 14 states and the District of Columbia and included semistructured interviews with staff performing home-infusion CLABSI surveillance. The results showed that the home-infusion CLABSI surveillance definition was valid and would be feasible to implement.
AHRQ-funded; HS027819.
Citation: Keller SC, Hannum SM, Weems K .
Implementing and validating a home-infusion central-line-associated bloodstream infection surveillance definition.
Infect Control Hosp Epidemiol 2023 Nov; 44(11):1748-59. doi: 10.1017/ice.2023.70..
Keywords: Home Healthcare, Central Line-Associated Bloodstream Infections (CLABSI), Healthcare-Associated Infections (HAIs)
Oladapo-Shittu O, Hannum SM, Salinas AB
The need to expand the infection prevention workforce in home infusion therapy.
This study looked at the prevalence of formal surveillance and infection prevention training for home infusion staff. The authors interviewed home infusion staff who perform surveillance activities about barriers to and facilitators for central line-associated bloodstream infection (CLABSI) surveillance and identified barriers to training in CLABSI surveillance. Their findings showed a lack of formal surveillance training which can be addressed by by adapting existing training resources to the home infusion setting.
AHRQ-funded; HS027819.
Citation: Oladapo-Shittu O, Hannum SM, Salinas AB .
The need to expand the infection prevention workforce in home infusion therapy.
Am J Infect Control 2023 May; 51(5):594-96. doi: 10.1016/j.ajic.2022.11.008.AHRQ-funded; HS027819..
Keywords: Healthcare-Associated Infections (HAIs), Prevention, Home Healthcare, Central Line-Associated Bloodstream Infections (CLABSI)
Goto M, Hasegawa S, Balkenende EC
Effectiveness of ultraviolet-c disinfection on hospital-onset gram-negative rod bloodstream infection: a nationwide stepped-wedge time-series analysis.
This study evaluated the effectiveness of enhanced terminal room cleaning with ultraviolet C (UV-C) disinfection in reducing gram-negative rod (GNR) infections. The authors used information regarding UV-C use and the timing of implementation through a survey of all Veterans Health Administration (VHA) hospitals providing inpatient acute care from January 2010 and December 2018. Among 128 Veterans Health Administration hospitals, 120 provided complete survey responses with 40 reporting implementations of UV-C systems. UV-C use was associated with a 19% lower incident of hospital-onset (HO) GNR bloodstream infection (BSI).
AHRQ-funded; HS027472.
Citation: Goto M, Hasegawa S, Balkenende EC .
Effectiveness of ultraviolet-c disinfection on hospital-onset gram-negative rod bloodstream infection: a nationwide stepped-wedge time-series analysis.
Clin Infect Dis 2023 Jan 13; 76(2):291-98. doi: 10.1093/cid/ciac776..
Keywords: Central Line-Associated Bloodstream Infections (CLABSI), Healthcare-Associated Infections (HAIs), Hospitals, Prevention, Sepsis
Patel SA, Araujo T, Rodriguez LP
Long peripheral catheters: a retrospective review of major complications.
The risk of infectious and noninfectious complications associated with long peripheral catheters (LPCs) is unknown. In this retrospective study of 539 catheters, the investigators did a retrospective review of major complications. Among other discoveries, they found LPCs were often placed for the indications of difficult access and long-term antibiotics.
AHRQ-funded; HS025891.
Citation: Patel SA, Araujo T, Rodriguez LP .
Long peripheral catheters: a retrospective review of major complications.
J Hosp Med 2019 Dec;14(12):758-60. doi: 10.12788/jhm.3313..
Keywords: Healthcare-Associated Infections (HAIs), Adverse Events, Patient Safety, Central Line-Associated Bloodstream Infections (CLABSI), Blood Clots, Infectious Diseases, Risk
Krein SL, Kuhn L, Ratz D
Use of designated nurse PICC teams and CLABSI prevention practices among U.S. hospitals: a survey-based study.
The authors identified the prevalence of and factors associated with having a designated nurse peripherally inserted central catheter (PICC) team among U.S. acute care hospitals. They found that nurse PICC teams inserted PICCs in more than 60% of U.S. hospitals during the study period. Moreover, certain practices to prevent central line-associated bloodstream infection, including maximum sterile barrier precautions, chlorhexidine gluconate for insertion site antisepsis, and facility-wide insertion checklists were regularly used by a higher percentage of hospitals with nurse PICC teams compared with those without. They concluded that nurse PICC teams play an integral role in PICC use at many hospitals and that use of such teams may promote key practices to prevent complications.
AHRQ-funded; HS022835.
Citation: Krein SL, Kuhn L, Ratz D .
Use of designated nurse PICC teams and CLABSI prevention practices among U.S. hospitals: a survey-based study.
J Patient Saf 2019 Dec;15(4):293-95. doi: 10.1097/pts.0000000000000246..
Keywords: Nursing, Teams, Central Line-Associated Bloodstream Infections (CLABSI), Healthcare-Associated Infections (HAIs), Inpatient Care, Hospitals, Patient Safety, Prevention, Provider: Nurse, Provider
Hefner JL, Fareed N, Walker DM
Central line infections in United States hospitals: an exploration of variation in central line device days and infection rates across hospitals that serve highly complex patient populations.
Am J Infect Control 2019 Aug;47(8):1032-34. doi: 10.1016/j.ajic.2018.12.001.
The authors’ descriptive analyses show a wide distribution in rates of central line device days and central line-associated bloodstream infections for a given standardized infection ratio among 215 US hospitals serving highly complex patient populations. They established that the standardized infection ratio masks hospital-level variation in device use and associated patient safety.
The authors’ descriptive analyses show a wide distribution in rates of central line device days and central line-associated bloodstream infections for a given standardized infection ratio among 215 US hospitals serving highly complex patient populations. They established that the standardized infection ratio masks hospital-level variation in device use and associated patient safety.
AHRQ-funded; HS024958.
Citation: Hefner JL, Fareed N, Walker DM .
Central line infections in United States hospitals: an exploration of variation in central line device days and infection rates across hospitals that serve highly complex patient populations.
Am J Infect Control 2019 Aug;47(8):1032-34. doi: 10.1016/j.ajic.2018.12.001..
Keywords: Central Line-Associated Bloodstream Infections (CLABSI), Healthcare-Associated Infections (HAIs), Patient Safety
Paje D, Rogers MAM, Conlon A
Use of peripherally inserted central catheters in patients with advanced chronic kidney disease: a prospective cohort study.
Existing guidelines, including Choosing Wisely recommendations, endorse avoiding placement of peripherally inserted central catheters (PICCs) in patients with chronic kidney disease (CKD). The purpose of this study was to describe the frequency of and characteristics associated with PICC use in hospitalized patients with stage 3b or greater CKD (glomerular filtration rate [GFR] <45 mL/min/1.73 m2).
AHRQ-funded; HS025891.
Citation: Paje D, Rogers MAM, Conlon A .
Use of peripherally inserted central catheters in patients with advanced chronic kidney disease: a prospective cohort study.
Ann Intern Med 2019 Jul 2;171(1):10-18. doi: 10.7326/m18-2937..
Keywords: Kidney Disease and Health, Guidelines, Evidence-Based Practice, Patient Safety, Central Line-Associated Bloodstream Infections (CLABSI), Healthcare-Associated Infections (HAIs)
Keller SC, Alexander M, Williams D
Perspectives on central-line-associated bloodstream infection surveillance in home infusion therapy.
This study examined in the differences between 3 professional society members who provide home infusion services in diagnosing and defining central-line-associated bloodstream infections (CLABSIs). The three societies surveyed were members of the Infusion Nurses Society (INS), the National Home Infusion Association (NHIA), and the Society for Healthcare Epidemiology of America Research Network (SRN). The INS is a 6000-member global organization of main nurses who work in all practice settings including home infusion. The NHIA is a 400-member trade organization focused on providing infusion products and services in the home, and SRN is a network of 111 healthcare institutions that collaborate on research to prevent healthcare-associated infections and antibiotic resistance. There was a difference in the criteria used for defining a CLABSI with home testing, and their use of the Association for Professionals in Infection Control/Healthcare Infection Control Practices Advisory Committee (APIC-HICPAC) criteria. Although some perspective was gained from a wide variety of professionals, there was a low response rate, which suggests the possibility of response bias.
AHRQ-funded; HS025782.
Citation: Keller SC, Alexander M, Williams D .
Perspectives on central-line-associated bloodstream infection surveillance in home infusion therapy.
Infect Control Hosp Epidemiol 2019 Jun;40(6):729-31. doi: 10.1017/ice.2019.90..
Keywords: Home Healthcare, Central Line-Associated Bloodstream Infections (CLABSI), Healthcare-Associated Infections (HAIs), Patient Safety
Leeman H, Cosgrove SE, Williams D
Assessing burden of central line-associated bloodstream infections present on hospital admission.
Investigators described patients presenting to an academic medical center with central line-associated bloodstream infection present on hospital admission over 1 year. Of the 130 admissions, they found that about half presented from home infusion, followed by oncology clinic, hemodialysis, and skilled nursing facility. They concluded that efforts to reduce such infections should address patients across the entire health care system.
AHRQ-funded; HS025782.
Citation: Leeman H, Cosgrove SE, Williams D .
Assessing burden of central line-associated bloodstream infections present on hospital admission.
Am J Infect Control 2020 Feb;48(2):216-18. doi: 10.1016/j.ajic.2019.08.010..
Keywords: Central Line-Associated Bloodstream Infections (CLABSI), Healthcare-Associated Infections (HAIs), Hospitalization, Home Healthcare, Hospitals, Infectious Diseases
Bozaan D, Skicki D, Brancaccio A
Less lumens-less risk: a pilot intervention to increase the use of single-lumen peripherally inserted central catheters.
To reduce risk of complications, existing guidelines recommend use of peripherally inserted central catheters (PICCs) with the minimal number of lumens. This recommendation, however, is difficult to implement in practice. The investigators conducted a pilot study to increase the use of single-lumen PICCs in hospitalized patients. The authors indicated that implementing a single-lumen PICC default and providing education and indications for multilumen devices improved PICC appropriateness.
AHRQ-funded; HS025891.
Citation: Bozaan D, Skicki D, Brancaccio A .
Less lumens-less risk: a pilot intervention to increase the use of single-lumen peripherally inserted central catheters.
J Hosp Med 2019 Jan 8;14(1):42-46. doi: 10.12788/jhm.3097..
Keywords: Central Line-Associated Bloodstream Infections (CLABSI), Healthcare-Associated Infections (HAIs), Adverse Events, Patient Safety, Risk