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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedTischendorf J, Brunner M, Knobloch MJ
Evaluation of a successful fluoroquinolone restriction intervention among high-risk patients: a mixed-methods study.
In this study, the investigators conducted a quality improvement initiative to restrict fluoroquinolone prescribing on two inpatient units housing high-risk patients and applied a human factors approach to understanding the barriers and facilitators to success of this intervention by front-line providers. The authors concluded that Fluoroquinolones can be safely restricted even among high-risk patients without negatively impacting length of stay, readmissions or mortality. Their study provides a framework for successful antimicrobial stewardship interventions informed by perceptions of front line providers.
AHRQ-funded; HS026226.
Citation: Tischendorf J, Brunner M, Knobloch MJ .
Evaluation of a successful fluoroquinolone restriction intervention among high-risk patients: a mixed-methods study.
PLoS One 2020 Aug 25;15(8):e0237987. doi: 10.1371/journal.pone.0237987..
Keywords: Antimicrobial Stewardship, Antibiotics, Medication, Risk
Trubiano JA, Vogrin S, Chua KYL
Development and validation of a penicillin allergy clinical decision rule.
Penicillin allergy is a significant public health issue for patients, antimicrobial stewardship programs, and health services. Validated clinical decision rules are urgently needed to identify low-risk penicillin allergies that potentially do not require penicillin skin testing by a specialist. The objective of this study was to develop and validate a penicillin allergy clinical decision rule that enables point-of-care risk assessment of patient-reported penicillin allergies.
AHRQ-funded; HS026395.
Citation: Trubiano JA, Vogrin S, Chua KYL .
Development and validation of a penicillin allergy clinical decision rule.
JAMA Intern Med 2020 May;180(5):745-52. doi: 10.1001/jamainternmed.2020.0403..
Keywords: Antimicrobial Stewardship, Antibiotics, Medication, Clinical Decision Support (CDS), Risk