National Healthcare Quality and Disparities Report
Latest available findings on quality of and access to health care
Data
- Data Infographics
- Data Visualizations
- Data Tools
- Data Innovations
- All-Payer Claims Database
- Healthcare Cost and Utilization Project (HCUP)
- Medical Expenditure Panel Survey (MEPS)
- AHRQ Quality Indicator Tools for Data Analytics
- State Snapshots
- United States Health Information Knowledgebase (USHIK)
- Data Sources Available from AHRQ
Search All Research Studies
Topics
- Cardiovascular Conditions (2)
- Chronic Conditions (1)
- (-) Diabetes (5)
- Electronic Health Records (EHRs) (1)
- Evidence-Based Practice (1)
- Health Information Technology (HIT) (1)
- Medication (3)
- Outcomes (1)
- Patient-Centered Healthcare (1)
- (-) Patient-Centered Outcomes Research (5)
- Patient Adherence/Compliance (1)
- (-) Risk (5)
AHRQ Research Studies
Sign up: AHRQ Research Studies Email updates
Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 5 of 5 Research Studies DisplayedMcCoy RG, Lipska KJ, Van Houten HK
Paradox of glycemic management: multimorbidity, glycemic control, and high-risk medication use among adults with diabetes.
Researchers examined contemporary patterns of glycemic control and use of medications known to cause hypoglycemia among adults with diabetes across age and multimorbidity. They found that the proportion of patients achieving low HbA1c levels was highest among older and multimorbid patients. Older patients and patients with higher comorbidity burden were more likely to be treated with insulin to achieve these HbA1c levels despite the potential for hypoglycemia and uncertain long-term benefit.
AHRQ-funded; HS024075.
Citation: McCoy RG, Lipska KJ, Van Houten HK .
Paradox of glycemic management: multimorbidity, glycemic control, and high-risk medication use among adults with diabetes.
BMJ Open Diabetes Res Care 2020 Feb;8(1). doi: 10.1136/bmjdrc-2019-001007..
Keywords: Diabetes, Medication, Patient-Centered Outcomes Research, Patient-Centered Healthcare, Evidence-Based Practice, Risk, Chronic Conditions
Flory JH, Keating SJ, Siscovick D
Identifying prevalence and risk factors for metformin non-persistence: a retrospective cohort study using an electronic health record.
Non-persistence may be a significant barrier to the use of metformin. The objective of this study was to assess reasons for metformin non-persistence, and whether initial metformin dosing or use of extended release (ER) formulations affect persistence to metformin therapy. The investigators concluded that their data supported the routine prescribing of low starting doses of metformin as a tool to improve persistence.
AHRQ-funded; HS023898.
Citation: Flory JH, Keating SJ, Siscovick D .
Identifying prevalence and risk factors for metformin non-persistence: a retrospective cohort study using an electronic health record.
BMJ Open 2018 Jul 23;8(7):e021505. doi: 10.1136/bmjopen-2018-021505..
Keywords: Diabetes, Electronic Health Records (EHRs), Health Information Technology (HIT), Medication, Patient Adherence/Compliance, Outcomes, Patient-Centered Outcomes Research, Risk
Pantalone KM, Misra-Hebert AD, Hobbs TM
Effect of glycemic control on the Diabetes Complications Severity Index score and development of complications in people with newly diagnosed type 2 diabetes.
The aim of the present study was to assess the longitudinal accumulation of diabetes-related complications and the effect of glycemic control on the Diabetes Complications Severity Index (DCSI) score in people with newly diagnosed type 2 diabetes (T2D). The study concluded that baseline glycemic control had no apparent effect on longitudinal changes in DCSI score. Worsening or persistently poor glycemic control was associated with an increased risk of an increase in the DCSI score.
Citation: Pantalone KM, Misra-Hebert AD, Hobbs TM .
Effect of glycemic control on the Diabetes Complications Severity Index score and development of complications in people with newly diagnosed type 2 diabetes.
J Diabetes 2018 Mar;10(3):192-99. doi: 10.1111/1753-0407.12613..
Keywords: Diabetes, Patient-Centered Outcomes Research, Risk
Flory JH, Ukena JK, Floyd JS
Novel anti-glycemic drugs and reduction of cardiovascular risk in diabetes: expectations realized, promises unmet.
The researchers review evidence on cardiovascular risks and benefits of new treatments for type 2 diabetes mellitus. Their review reports new evidence suggesting that the newest diabetes drugs are safe from a cardiovascular perspective. Evidence on benefit from at least some members of the GLP-1 receptor agonist and SGLT-2 inhibitor classes is encouraging but not yet decisive.
AHRQ-funded; HS023898.
Citation: Flory JH, Ukena JK, Floyd JS .
Novel anti-glycemic drugs and reduction of cardiovascular risk in diabetes: expectations realized, promises unmet.
Curr Atheroscler Rep 2016 Dec;18(12):79. doi: 10.1007/s11883-016-0633-y.
.
.
Keywords: Patient-Centered Outcomes Research, Medication, Diabetes, Cardiovascular Conditions, Risk
Vazquez-Benitez G, Desai JR, Xu S
Preventable major cardiovascular events associated with uncontrolled glucose, blood pressure, and lipids and active smoking in adults with diabetes with and without cardiovascular disease: a contemporary analysis.
The objective of this study was to assess the incidence of major cardiovascular (CV) hospitalization events and all-cause deaths among adults with diabetes with or without CV disease (CVD) associated with inadequately controlled glycated hemoglobin, high LDL cholesterol, high blood pressure, and current smoking. It found that the percentages of CV events associated with inadequate risk factor control were 11 percent for those with CVD and 34 percent for those without CVD.
AHRQ-funded; HS019859.
Citation: Vazquez-Benitez G, Desai JR, Xu S .
Preventable major cardiovascular events associated with uncontrolled glucose, blood pressure, and lipids and active smoking in adults with diabetes with and without cardiovascular disease: a contemporary analysis.
Diabetes Care 2015 May;38(5):905-12. doi: 10.2337/dc14-1877..
Keywords: Diabetes, Cardiovascular Conditions, Risk, Patient-Centered Outcomes Research